MX2017015190A - Metodos de diagnostico para tratamiento con linfocitos t. - Google Patents
Metodos de diagnostico para tratamiento con linfocitos t.Info
- Publication number
- MX2017015190A MX2017015190A MX2017015190A MX2017015190A MX2017015190A MX 2017015190 A MX2017015190 A MX 2017015190A MX 2017015190 A MX2017015190 A MX 2017015190A MX 2017015190 A MX2017015190 A MX 2017015190A MX 2017015190 A MX2017015190 A MX 2017015190A
- Authority
- MX
- Mexico
- Prior art keywords
- cell therapy
- patient
- diagnostic methods
- prior
- identifying
- Prior art date
Links
- 238000002659 cell therapy Methods 0.000 title abstract 7
- 238000002405 diagnostic procedure Methods 0.000 title 1
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 6
- 230000003750 conditioning effect Effects 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 102000004127 Cytokines Human genes 0.000 abstract 1
- 108090000695 Cytokines Proteins 0.000 abstract 1
- 239000000090 biomarker Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
Classifications
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- A61K40/4202—Receptors, cell surface antigens or cell surface determinants
- A61K40/421—Immunoglobulin superfamily
- A61K40/4211—CD19 or B4
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- C07K14/7051—T-cell receptor (TcR)-CD3 complex
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- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/03—Fusion polypeptide containing a localisation/targetting motif containing a transmembrane segment
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Abstract
La invención proporciona métodos para incrementar la eficacia de un tratamiento con linfocitos T en un paciente en necesidad de los mismos. La invención incluye un método para acondicionar un paciente antes de un tratamiento con linfocitos T, en donde el acondicionamiento involucra administrar una combinación de ciclofosfamida y fludarabina.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562167738P | 2015-05-28 | 2015-05-28 | |
| US201562262111P | 2015-12-02 | 2015-12-02 | |
| PCT/US2016/034885 WO2016191755A1 (en) | 2015-05-28 | 2016-05-27 | Diagnostic methods for t cell therapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2017015190A true MX2017015190A (es) | 2018-07-06 |
| MX388325B MX388325B (es) | 2025-03-19 |
Family
ID=57393492
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2017015190A MX388325B (es) | 2015-05-28 | 2016-05-27 | Metodos de diagnostico para tratamiento con linfocitos t. |
| MX2021014047A MX2021014047A (es) | 2015-05-28 | 2017-11-27 | Metodos de diagnostico para tratamiento con linfocitos t. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2021014047A MX2021014047A (es) | 2015-05-28 | 2017-11-27 | Metodos de diagnostico para tratamiento con linfocitos t. |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US11779601B2 (es) |
| EP (2) | EP4218778A3 (es) |
| JP (4) | JP6917903B2 (es) |
| KR (4) | KR20230148387A (es) |
| CN (2) | CN107921064A (es) |
| AU (3) | AU2016268863B2 (es) |
| BR (1) | BR122023022076A2 (es) |
| CA (1) | CA2986793A1 (es) |
| CL (1) | CL2017003005A1 (es) |
| DO (1) | DOP2017000272A (es) |
| EA (1) | EA201792642A1 (es) |
| ES (1) | ES2944962T3 (es) |
| HK (1) | HK1251960A1 (es) |
| IL (2) | IL255888B2 (es) |
| MA (1) | MA45281A (es) |
| MX (2) | MX388325B (es) |
| PH (1) | PH12017502153A1 (es) |
| PL (1) | PL3302507T3 (es) |
| PT (1) | PT3302507T (es) |
| SG (2) | SG10201913620QA (es) |
| SI (1) | SI3302507T1 (es) |
| WO (1) | WO2016191755A1 (es) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014117121A1 (en) | 2013-01-28 | 2014-07-31 | St. Jude Children's Research Hospital, Inc. | A chimeric receptor with nkg2d specificity for use in cell therapy against cancer and infectious disease |
| KR102211120B1 (ko) | 2014-05-15 | 2021-02-03 | 내셔널 유니버시티 오브 싱가포르 | 변형된 천연 살해 세포 및 그의 용도 |
| IL255887B (en) * | 2015-05-28 | 2022-09-01 | Kite Pharma Inc | Methods for training patients for t-cell therapy |
| CN107921064A (zh) | 2015-05-28 | 2018-04-17 | 凯德药业股份有限公司 | 用于t细胞疗法的诊断方法 |
| CA3053539A1 (en) | 2017-02-27 | 2018-08-30 | Juno Therapeutics, Inc. | Compositions, articles of manufacture and methods related to dosing in cell therapy |
| IL269553B2 (en) | 2017-03-27 | 2025-10-01 | Nat Univ Singapore | Truncated NKG2D chimeric receptors and their uses in immunotherapy with natural killer cells |
| WO2018182511A1 (en) | 2017-03-27 | 2018-10-04 | National University Of Singapore | Stimulatory cell lines for ex vivo expansion and activation of natural killer cells |
| SG11201908980PA (en) | 2017-04-03 | 2019-10-30 | Kite Pharma Inc | Treatment using chimeric receptor t cells incorporating optimized polyfunctional t cells |
| CN111225675B (zh) | 2017-06-02 | 2024-05-03 | 朱诺治疗学股份有限公司 | 使用过继细胞疗法治疗的制品和方法 |
| MA50855A (fr) | 2017-11-01 | 2020-09-09 | Juno Therapeutics Inc | Procédé de génération de compositions thérapeutiques de cellules modifiées |
| US12031975B2 (en) | 2017-11-01 | 2024-07-09 | Juno Therapeutics, Inc. | Methods of assessing or monitoring a response to a cell therapy |
| EP3720480A2 (en) | 2017-12-08 | 2020-10-14 | Juno Therapeutics, Inc. | Phenotypic markers for cell therapy and related methods |
| CN111801348A (zh) | 2018-02-09 | 2020-10-20 | 新加坡国立大学 | 活化性嵌合受体及其在自然杀伤细胞免疫疗法中的用途 |
| SG11202008976YA (en) | 2018-04-02 | 2020-10-29 | Nat Univ Singapore | Neutralization of human cytokines with membrane-bound anti-cytokine non-signaling binders expressed in immune cells |
| WO2019207942A1 (ja) * | 2018-04-27 | 2019-10-31 | OTA Takayo | 免疫チェックポイント阻害剤によるがん治療の効果を評価するためのバイオマーカー |
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