MX2019002425A - Micro ácidos ribonucleicos como biomarcadores para la endometriosis. - Google Patents

Micro ácidos ribonucleicos como biomarcadores para la endometriosis.

Info

Publication number
MX2019002425A
MX2019002425A MX2019002425A MX2019002425A MX2019002425A MX 2019002425 A MX2019002425 A MX 2019002425A MX 2019002425 A MX2019002425 A MX 2019002425A MX 2019002425 A MX2019002425 A MX 2019002425A MX 2019002425 A MX2019002425 A MX 2019002425A
Authority
MX
Mexico
Prior art keywords
endometriosis
micrornas
biomarkers
mirna
characterization
Prior art date
Application number
MX2019002425A
Other languages
English (en)
Inventor
Taylor Hugh
Original Assignee
Univ Yale
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Yale filed Critical Univ Yale
Publication of MX2019002425A publication Critical patent/MX2019002425A/es

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/689—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/36—Gynecology or obstetrics
    • G01N2800/364—Endometriosis, i.e. non-malignant disorder in which functioning endometrial tissue is present outside the uterine cavity

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • Reproductive Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biophysics (AREA)
  • Pregnancy & Childbirth (AREA)
  • General Engineering & Computer Science (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)

Abstract

Se describen en la presente composiciones y metodos utiles para el diagnostico, evaluacion y caracterizacion de la endometriosis en un sujeto que lo necesite, con base en el nivel de expresion de al menos un miARN que se asocia con la endometriosis.
MX2019002425A 2016-08-30 2017-08-30 Micro ácidos ribonucleicos como biomarcadores para la endometriosis. MX2019002425A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662381130P 2016-08-30 2016-08-30
PCT/US2017/049284 WO2018044979A1 (en) 2016-08-30 2017-08-30 Micrornas as biomarkers for endometriosis

Publications (1)

Publication Number Publication Date
MX2019002425A true MX2019002425A (es) 2019-08-16

Family

ID=61301726

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2019002425A MX2019002425A (es) 2016-08-30 2017-08-30 Micro ácidos ribonucleicos como biomarcadores para la endometriosis.

Country Status (11)

Country Link
US (3) US10982282B2 (es)
EP (1) EP3506912B1 (es)
JP (2) JP2019528081A (es)
KR (1) KR20190057305A (es)
CN (1) CN109890394A (es)
AU (1) AU2017319325A1 (es)
BR (1) BR112019004075A2 (es)
CA (1) CA3035429A1 (es)
MX (1) MX2019002425A (es)
SG (2) SG11201901834WA (es)
WO (1) WO2018044979A1 (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3800267A1 (en) 2014-03-27 2021-04-07 Yale University Circulating micrornas as biomarkers for endometriosis
CN109890394A (zh) 2016-08-30 2019-06-14 耶鲁大学 作为子宫内膜异位症的生物标志物的微小rna
CN111295453A (zh) * 2017-08-30 2020-06-16 圆点实验室公司 用于检测和治疗子宫内膜异位症的方法和组合物
EP3820483A4 (en) 2018-07-13 2023-03-01 Yale University COMPOSITIONS AND METHODS FOR THE TREATMENT OF ENDOMETRIOSIS
KR102089559B1 (ko) 2018-08-31 2020-03-16 차의과학대학교 산학협력단 난소의 fsh에 대한 반응성의 진단 또는 예측용 바이오마커 및 이의 용도
CA3118133A1 (en) * 2018-10-31 2020-05-07 Yale University A quantitative algorithm for endometriosis
US11315660B2 (en) 2018-10-31 2022-04-26 Dot Laboratories, Inc. Method of detecting and treating endometriosis in a female subject
WO2020146544A1 (en) * 2019-01-09 2020-07-16 Research Institute At Nationwide Children's Hospital A novel method for monitoring endometriosis and associated disorders
WO2020179895A1 (ja) 2019-03-07 2020-09-10 東レ株式会社 子宮平滑筋肉腫の検出のためのキット、デバイス及び方法
ES2787725A1 (es) * 2019-04-15 2020-10-16 Univ Granada Metodo de obtencion de datos utiles para diagnosticar telangiectasia hemorragica hereditaria
CN110144394A (zh) * 2019-04-18 2019-08-20 辽宁省肿瘤医院 一种子宫内膜异位症诊断、预后标志物及其应用
EP4004553A1 (en) 2019-07-22 2022-06-01 F. Hoffmann-La Roche AG S100a8 as blood biomarker for the non-invasive diagnosis of endometriosis
EP4004554A1 (en) * 2019-07-22 2022-06-01 F. Hoffmann-La Roche AG S100a9 as blood biomarker for the non-invasive diagnosis of endometriosis
WO2021013781A1 (en) * 2019-07-22 2021-01-28 F. Hoffmann-La Roche Ag Substance p as blood biomarker for the non-invasive diagnosis of endometriosis
US11965879B2 (en) 2019-08-23 2024-04-23 Mcmaster University Method for diagnosing and assessing endometriosis
KR102242639B1 (ko) * 2020-01-28 2021-04-21 고려대학교 산학협력단 간 섬유화 진단용 바이오마커 miRNA4668-5p
KR102316507B1 (ko) * 2020-02-28 2021-10-22 차의과학대학교 산학협력단 난소 예비력 바이오마커 및 이의 용도
CN111909997B (zh) * 2020-09-09 2021-09-28 上海交通大学 miRNA标志物在制备奥氮平治疗精神分裂症疗效评估方面的产品中的应用及试剂盒
JP2022063860A (ja) * 2020-10-12 2022-04-22 学校法人近畿大学 ホウ素化合物およびその製造方法
KR102940037B1 (ko) * 2022-12-06 2026-03-16 연세대학교 산학협력단 자궁내막증 진단용 조성물

Family Cites Families (20)

* Cited by examiner, † Cited by third party
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US20090317820A1 (en) 2008-05-19 2009-12-24 The Regents Of The University Of California Micro-rna profile in human saliva and its use for detection of oral cancer
CA2743211A1 (en) 2008-11-12 2010-05-20 Caris Life Sciences Luxembourg Holdings, S.A.R.L. Methods and systems of using exosomes for determining phenotypes
WO2010118979A1 (en) 2009-04-07 2010-10-21 Velin-Pharma A/S Method and device for treatment of conditions associated with inflammation or undesirable activation of the immune system
US9128101B2 (en) * 2010-03-01 2015-09-08 Caris Life Sciences Switzerland Holdings Gmbh Biomarkers for theranostics
US20120244530A1 (en) * 2011-01-26 2012-09-27 Cepheid Methods of detecting lung cancer
WO2012112883A1 (en) 2011-02-18 2012-08-23 Yale University The kras-variant and endometriosis
FR2984358A1 (fr) 2011-12-16 2013-06-21 Genethon Methodes pour le diagnostic de dystrophies musculaires
WO2013148151A1 (en) 2012-03-29 2013-10-03 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Plasma microribonucleic acids as biomarkers for endometriosis and endometriosis-associated ovarian cancer
US10927412B2 (en) 2013-10-01 2021-02-23 The Regents Of The University Of California Endometriosis classifier
JP6930832B2 (ja) * 2013-11-18 2021-09-01 ディアミール, エルエルシーDiamir, Llc パーキンソン病（ＰＤ）の検出およびモニタリングのための、体液からのｍｉＲＮＡを使用する方法
GB201403489D0 (en) * 2014-02-27 2014-04-16 Univ London Queen Mary Biomarkers for endometriosis
US9650676B2 (en) 2014-03-19 2017-05-16 University Of South Carolina Leukocyte MicroRNAS for use in diagnosis and treatment of endometriosis
EP3800267A1 (en) 2014-03-27 2021-04-07 Yale University Circulating micrornas as biomarkers for endometriosis
EP2924126B1 (en) * 2014-03-28 2018-04-18 Tervisetehnoloogiate Arenduskeskus AS Method for using microRNA (miRNA) for detection of endometriosis
GB201603967D0 (en) * 2016-03-08 2016-04-20 Univ Birmingham Biomarkers of traumatic brain injury
CN109890394A (zh) 2016-08-30 2019-06-14 耶鲁大学 作为子宫内膜异位症的生物标志物的微小rna
CN111295453A (zh) 2017-08-30 2020-06-16 圆点实验室公司 用于检测和治疗子宫内膜异位症的方法和组合物
CA3118133A1 (en) 2018-10-31 2020-05-07 Yale University A quantitative algorithm for endometriosis
US11315660B2 (en) 2018-10-31 2022-04-26 Dot Laboratories, Inc. Method of detecting and treating endometriosis in a female subject
CA3134382A1 (en) 2019-04-29 2020-11-05 Hugh Taylor Classifiers for detection of endometriosis

Also Published As

Publication number Publication date
AU2017319325A1 (en) 2019-03-21
US20210180134A1 (en) 2021-06-17
KR20190057305A (ko) 2019-05-28
EP3506912A4 (en) 2020-08-19
WO2018044979A1 (en) 2018-03-08
SG10202102509TA (en) 2021-04-29
SG11201901834WA (en) 2019-03-28
US12077803B2 (en) 2024-09-03
US10982282B2 (en) 2021-04-20
BR112019004075A2 (pt) 2019-05-28
US11220713B2 (en) 2022-01-11
JP2019528081A (ja) 2019-10-10
CA3035429A1 (en) 2018-03-08
JP2022188086A (ja) 2022-12-20
US20220049312A1 (en) 2022-02-17
CN109890394A (zh) 2019-06-14
EP3506912A1 (en) 2019-07-10
EP3506912B1 (en) 2024-04-03
US20190276893A1 (en) 2019-09-12

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