MX2019012803A - Nuevos derivados de pirazol biciclicos. - Google Patents

Nuevos derivados de pirazol biciclicos.

Info

Publication number
MX2019012803A
MX2019012803A MX2019012803A MX2019012803A MX2019012803A MX 2019012803 A MX2019012803 A MX 2019012803A MX 2019012803 A MX2019012803 A MX 2019012803A MX 2019012803 A MX2019012803 A MX 2019012803A MX 2019012803 A MX2019012803 A MX 2019012803A
Authority
MX
Mexico
Prior art keywords
compounds
pyrazole derivatives
bicyclic pyrazole
new bicyclic
preparing
Prior art date
Application number
MX2019012803A
Other languages
English (en)
Inventor
Schwarz Hans-Georg
Köbberling Johannes
Hübsch Walter
Welz Claudia
Zhuang Wei
Köhler Adeline
Kulke Daniel
Griebenow Nils
Görgens Ulrich
Ilg Thomas
Original Assignee
Bayer Animal Health Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Animal Health Gmbh filed Critical Bayer Animal Health Gmbh
Publication of MX2019012803A publication Critical patent/MX2019012803A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
    • C07D513/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

La invención abarca nuevos compuestos de pirazol bicíclicos de la fórmula general (I): (ver Fórmula) en la cual G, A, R1, R2, R3 y Q son como se definen en el presente, procedimientos para la elaboración de dichos compuestos, compuestos intermedios útiles para la elaboración de dichos compuestos, composiciones farmacéuticas y combinaciones que comprenden dichos compuestos y el uso de dichos compuestos para la elaboración de composiciones farmacéuticas para el tratamiento, control y/o prevención de enfermedades, en particular de infecciones con helmintos, como un único agente o en combinación con otros principios activos.
MX2019012803A 2017-04-27 2018-04-23 Nuevos derivados de pirazol biciclicos. MX2019012803A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP17168558 2017-04-27
PCT/EP2018/060313 WO2018197401A1 (en) 2017-04-27 2018-04-23 New bicyclic pyrazole derivatives

Publications (1)

Publication Number Publication Date
MX2019012803A true MX2019012803A (es) 2020-01-23

Family

ID=58638808

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2019012803A MX2019012803A (es) 2017-04-27 2018-04-23 Nuevos derivados de pirazol biciclicos.

Country Status (20)

Country Link
US (1) US11130768B2 (es)
EP (1) EP3585791B1 (es)
JP (1) JP7261747B2 (es)
KR (1) KR102596307B1 (es)
CN (1) CN110536892B (es)
AU (1) AU2018257582B2 (es)
CA (1) CA3061406A1 (es)
CL (1) CL2019003078A1 (es)
CO (1) CO2019011877A2 (es)
DK (1) DK3585791T3 (es)
DO (1) DOP2019000275A (es)
ES (1) ES2998110T3 (es)
MX (1) MX2019012803A (es)
PH (1) PH12019502365A1 (es)
PL (1) PL3585791T3 (es)
SG (1) SG11201909243TA (es)
TW (1) TWI780147B (es)
UY (1) UY37705A (es)
WO (1) WO2018197401A1 (es)
ZA (1) ZA201907834B (es)

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MX2021007538A (es) 2018-12-18 2021-10-13 Elanco Tiergesundheit Ag Derivados biciclicos.
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US12448391B2 (en) 2019-06-07 2025-10-21 Elanco Tiergesundheit Ag Bicyclic derivatives for treating endoparasites
BR112022012130A2 (pt) * 2019-12-18 2022-08-30 Intervet Int Bv Compostos antelmínticos compreendendo uma estrutura azaindólica
KR20230028268A (ko) 2020-05-29 2023-02-28 뵈링거 잉겔하임 애니멀 헬스 유에스에이 인코포레이티드 구충성 헤테로시클릭 화합물
WO2022106469A2 (en) 2020-11-18 2022-05-27 Elanco Tiergesundheit Ag N-(2,3-dihydro-1,4-benzoxazin-4-yl)-3-isopropyl-7-(2,3,5-trifluorophenyl)benzo-thiophene-2-carboxamide derivatives and similar compounds for the treatment of heartworm infections
TW202237600A (zh) 2020-12-04 2022-10-01 瑞士商禮藍動物保健股份有限公司 雙環衍生物
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WO2024213752A1 (en) 2023-04-14 2024-10-17 Elanco Animal Health Gmbh Long-term prevention and/or treatment of a disease by slo-1 inhibitors
CN121620507A (zh) 2023-08-02 2026-03-06 英特维特国际股份有限公司 具有驱虫活性的甲酰胺-4-喹啉化合物
WO2026078157A2 (en) 2024-10-10 2026-04-16 Elanco Animal Health Gmbh Slo-1 modulators for prevention and/or treatment of a disease

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Also Published As

Publication number Publication date
PH12019502365A1 (en) 2020-10-26
EP3585791A1 (en) 2020-01-01
RU2019138221A (ru) 2021-05-27
UY37705A (es) 2018-11-30
JP7261747B2 (ja) 2023-04-20
AU2018257582B2 (en) 2022-06-16
ZA201907834B (en) 2022-06-29
DOP2019000275A (es) 2019-11-15
KR102596307B1 (ko) 2023-10-30
DK3585791T3 (da) 2024-12-02
RU2019138221A3 (es) 2021-05-27
US20200190111A1 (en) 2020-06-18
CL2019003078A1 (es) 2020-04-03
EP3585791B1 (en) 2024-10-16
TW201841925A (zh) 2018-12-01
BR112019022383A2 (pt) 2020-05-19
PL3585791T3 (pl) 2025-03-17
CO2019011877A2 (es) 2020-01-17
KR20190141725A (ko) 2019-12-24
JP2020517683A (ja) 2020-06-18
US11130768B2 (en) 2021-09-28
WO2018197401A1 (en) 2018-11-01
ES2998110T3 (en) 2025-02-19
AU2018257582A1 (en) 2019-10-24
CA3061406A1 (en) 2018-11-01
SG11201909243TA (en) 2019-11-28
CN110536892A (zh) 2019-12-03
TWI780147B (zh) 2022-10-11
CN110536892B (zh) 2023-05-12

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