MX2020003144A - Nuevos complejos de polipeptidos biespecificos cd3/cd19. - Google Patents

Nuevos complejos de polipeptidos biespecificos cd3/cd19.

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Publication number
MX2020003144A
MX2020003144A MX2020003144A MX2020003144A MX2020003144A MX 2020003144 A MX2020003144 A MX 2020003144A MX 2020003144 A MX2020003144 A MX 2020003144A MX 2020003144 A MX2020003144 A MX 2020003144A MX 2020003144 A MX2020003144 A MX 2020003144A
Authority
MX
Mexico
Prior art keywords
polypeptide complex
bispecific
biespecific
polypeptides
new complexes
Prior art date
Application number
MX2020003144A
Other languages
English (en)
Inventor
Jing Li
Jianqing Xu
Zhuozhi Wang
Qin Mei
Jieying Liu
Original Assignee
Wuxi Biologics Ireland Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wuxi Biologics Ireland Ltd filed Critical Wuxi Biologics Ireland Ltd
Publication of MX2020003144A publication Critical patent/MX2020003144A/es

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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K16/46—Hybrid immunoglobulins
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    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
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Abstract

Se proporcionan un complejo de polipéptidos biespecíficos anti-CD3 x CD19 que contiene un primer resto de unión a antígeno del complejo de polipéptidos y un segundo resto de unión a antígeno, métodos para producir el complejo de polipéptidos biespecíficos anti-CD3 x CD19, métodos para tratar enfermedad o trastorno usando el complejo de polipéptidos biespecíficos anti- CD3 x CD19, polinucleótidos que codifican el complejo de polipéptidos biespecíficos anti-CD3 x CD19, vectores y células huésped que contienen dichos polinucleótidos, y composiciones y composiciones farmacéuticas que comprenden el complejo de polipéptidos biespecíficos anti-CD3 x 10 CD19.
MX2020003144A 2017-09-22 2018-09-20 Nuevos complejos de polipeptidos biespecificos cd3/cd19. MX2020003144A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN2017103032 2017-09-22
PCT/CN2018/106776 WO2019057124A1 (en) 2017-09-22 2018-09-20 NEW BISPECIFIC CD3 / CD19 POLYPEPTIDE COMPLEXES

Publications (1)

Publication Number Publication Date
MX2020003144A true MX2020003144A (es) 2020-07-28

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Application Number Title Priority Date Filing Date
MX2020003144A MX2020003144A (es) 2017-09-22 2018-09-20 Nuevos complejos de polipeptidos biespecificos cd3/cd19.

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Country Link
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