MX2020004094A - Metodos para administrar inmunoterapia con receptores de antigeno quimerico. - Google Patents

Metodos para administrar inmunoterapia con receptores de antigeno quimerico.

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Publication number
MX2020004094A
MX2020004094A MX2020004094A MX2020004094A MX2020004094A MX 2020004094 A MX2020004094 A MX 2020004094A MX 2020004094 A MX2020004094 A MX 2020004094A MX 2020004094 A MX2020004094 A MX 2020004094A MX 2020004094 A MX2020004094 A MX 2020004094A
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Mexico
Prior art keywords
methods
cell
cell lymphoma
chimeric antigen
antigen receptors
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MX2020004094A
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English (en)
Other versions
MX421741B (es
Inventor
Jeffrey S Wiezorek
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Kite Pharma Inc
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Publication of MX2020004094A publication Critical patent/MX2020004094A/es
Publication of MX421741B publication Critical patent/MX421741B/es

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    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001102—Receptors, cell surface antigens or cell surface determinants
    • A61K39/001111—Immunoglobulin superfamily
    • A61K39/001112—CD19 or B4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/31—Chimeric antigen receptors [CAR]
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
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    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A61K40/4202—Receptors, cell surface antigens or cell surface determinants
    • A61K40/421—Immunoglobulin superfamily
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
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    • A61K2239/48—Blood cells, e.g. leukemia or lymphoma
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    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1816—Erythropoietin [EPO]
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    • A61K38/19—Cytokines; Lymphokines; Interferons
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    • A61K38/34—Melanocyte stimulating hormone [MSH], e.g. alpha- or beta-melanotropin
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    • A61K38/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • A61K38/35—Corticotropin [ACTH]

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Abstract

La presente divulgación proporciona células que comprenden inmunoterapia con células T autólogas modificadas genéticamente dirigidas a CD19 para el tratamiento de, por ejemplo, linfoma de células B grandes recidivante o refractario después de dos o más líneas de terapia sistémica, incluyendo linfoma difuso de células B grandes (LDCBG) no especificado de otra manera, linfoma mediastínico primario de células B grandes, linfoma de células B de alto grado y LDCBG derivado de linfoma folicular. Algunos aspectos de la divulgación se refieren a métodos de tratamiento y monitoreo después de la infusión de la terapia con células T proporcionada en la presente.
MX2020004094A 2017-10-18 2018-10-18 Inmunoterapia con receptores de antígeno quimérico y uso de la misma MX421741B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762574159P 2017-10-18 2017-10-18
PCT/US2018/056467 WO2019079564A1 (en) 2017-10-18 2018-10-18 METHODS OF DELIVERY OF CHIMERIC ANTIGEN RECEPTOR IMMUNOTHERAPY

Publications (2)

Publication Number Publication Date
MX2020004094A true MX2020004094A (es) 2020-07-21
MX421741B MX421741B (es) 2025-03-14

Family

ID=64477267

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2020004094A MX421741B (es) 2017-10-18 2018-10-18 Inmunoterapia con receptores de antígeno quimérico y uso de la misma
MX2025002021A MX2025002021A (es) 2017-10-18 2020-07-13 Inmunoterapia con receptores de antigeno quimerico y uso de la misma

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2025002021A MX2025002021A (es) 2017-10-18 2020-07-13 Inmunoterapia con receptores de antigeno quimerico y uso de la misma

Country Status (15)

Country Link
US (1) US20190151361A1 (es)
EP (1) EP3697500A1 (es)
JP (3) JP2021500333A (es)
KR (3) KR20200071753A (es)
CN (1) CN111479613A (es)
AR (1) AR113777A1 (es)
AU (4) AU2018351046A1 (es)
BR (1) BR112020007493A2 (es)
CA (1) CA3084470A1 (es)
CO (1) CO2020004804A2 (es)
IL (2) IL273629B2 (es)
MX (2) MX421741B (es)
SG (1) SG11202003380TA (es)
TW (1) TWI866888B (es)
WO (1) WO2019079564A1 (es)

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JP2026048753A (ja) 2026-03-17
IL273629A (en) 2020-05-31
TW202510896A (zh) 2025-03-16
KR20250054837A (ko) 2025-04-23
CO2020004804A2 (es) 2020-05-05
NZ763357A (en) 2023-10-27
AU2025220739A1 (en) 2025-09-11
MX421741B (es) 2025-03-14
SG11202003380TA (en) 2020-05-28
JP2021500333A (ja) 2021-01-07
KR20230011487A (ko) 2023-01-20
IL273629B2 (en) 2025-10-01
IL273629B1 (en) 2025-06-01
KR20200071753A (ko) 2020-06-19
AU2023202308A1 (en) 2023-05-11
US20190151361A1 (en) 2019-05-23
TW201927315A (zh) 2019-07-16
AU2023202308B2 (en) 2025-05-22
EP3697500A1 (en) 2020-08-26
IL320802A (en) 2025-07-01
AU2018351046A1 (en) 2020-04-30
WO2019079564A1 (en) 2019-04-25
US20240058381A1 (en) 2024-02-22
MX2025002021A (es) 2025-04-02
AU2021282551B2 (en) 2023-01-19
BR112020007493A2 (pt) 2020-10-27
TWI866888B (zh) 2024-12-21
AU2021282551A1 (en) 2022-01-06
AR113777A1 (es) 2020-06-10
CA3084470A1 (en) 2019-04-25
JP2023154073A (ja) 2023-10-18
CN111479613A (zh) 2020-07-31

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