MX2020004949A - Arn no codificante para la deteccion de cancer. - Google Patents

Arn no codificante para la deteccion de cancer.

Info

Publication number
MX2020004949A
MX2020004949A MX2020004949A MX2020004949A MX2020004949A MX 2020004949 A MX2020004949 A MX 2020004949A MX 2020004949 A MX2020004949 A MX 2020004949A MX 2020004949 A MX2020004949 A MX 2020004949A MX 2020004949 A MX2020004949 A MX 2020004949A
Authority
MX
Mexico
Prior art keywords
detection
cancer
coding rna
sample
noncoding
Prior art date
Application number
MX2020004949A
Other languages
English (en)
Inventor
Hani Goodarzi
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Publication of MX2020004949A publication Critical patent/MX2020004949A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • C12Q1/485—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/07—Nucleotidyltransferases (2.7.7)
    • C12Y207/07049—RNA-directed DNA polymerase (2.7.7.49), i.e. telomerase or reverse-transcriptase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente divulgación se refiere en general a la detección de moléculas de ARN no codificantes en una muestra o al diagnóstico del sujeto en base a la detección o cuantificación de secuencias de ácidos nucleicos no codificantes en una muestra, específicamente para identificar y usar biomarcadores moleculares para el cáncer, incluido el cáncer de mama.
MX2020004949A 2017-11-12 2018-11-09 Arn no codificante para la deteccion de cancer. MX2020004949A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762584899P 2017-11-12 2017-11-12
PCT/US2018/060113 WO2019094780A2 (en) 2017-11-12 2018-11-09 Non-coding rna for detection of cancer

Publications (1)

Publication Number Publication Date
MX2020004949A true MX2020004949A (es) 2020-08-27

Family

ID=66439063

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2020004949A MX2020004949A (es) 2017-11-12 2018-11-09 Arn no codificante para la deteccion de cancer.

Country Status (8)

Country Link
US (4) US20200362420A1 (es)
EP (1) EP3707259A4 (es)
JP (3) JP7549880B2 (es)
CN (1) CN111344409A (es)
AU (2) AU2018364987A1 (es)
CA (1) CA3082391A1 (es)
MX (1) MX2020004949A (es)
WO (1) WO2019094780A2 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3571315B1 (en) 2017-01-23 2025-01-08 Gatehouse Bio, Inc. Methods for identifying and using small rna predictors
US20230027285A1 (en) * 2019-11-21 2023-01-26 Icahn School Of Medicine At Mount Sinai Small unannotated, non-coding rnas for the detection of liver cancer
WO2021150990A1 (en) * 2020-01-22 2021-07-29 Srnalytics, Inc. Small rna disease classifiers
WO2022029488A1 (en) * 2020-08-06 2022-02-10 Agenda Nv Systems and methods of assessing breast cancer
AU2021329814A1 (en) * 2020-08-16 2023-03-23 The Regents Of The University Of California System and methods of detection of oncrnas for cancer diagnosis
WO2022101672A2 (en) 2020-11-11 2022-05-19 Agendia NV Method of assessing diseases using image classifiers
EP4500535A4 (en) * 2022-03-29 2026-04-15 Univ California METHODS FOR DETERMINING THE PRESENCE, TYPE, GRADE, AND CLASSIFICATION OF A TUMOR, CYST, LESION, MASS, AND/OR CANCER
WO2025033530A1 (ja) * 2023-08-10 2025-02-13 国立大学法人山口大学 大腸癌の診断マーカー

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070065844A1 (en) * 2005-06-08 2007-03-22 Massachusetts Institute Of Technology Solution-based methods for RNA expression profiling
US20080076674A1 (en) * 2006-07-06 2008-03-27 Thomas Litman Novel oligonucleotide compositions and probe sequences useful for detection and analysis of non coding RNAs associated with cancer
WO2008109556A1 (en) * 2007-03-02 2008-09-12 Mdrna, Inc. Nucleic acid compounds for inhibiting telomerase gene expression and uses thereof
CN102027129B (zh) * 2008-02-28 2014-03-12 俄亥俄州立大学研究基金会 用于前列腺相关病症的诊断、预后和治疗的基于微rna的方法和组合物
US20110136124A1 (en) * 2009-09-23 2011-06-09 Wilson Roa Microrna expression profiles associated with lung cancer
EP2388336A1 (en) * 2010-05-19 2011-11-23 Signature Diagnostics AG Method and kits for diagnosing colorectal cancer
EP2640854B1 (en) * 2010-11-19 2018-02-21 The Regents Of The University Of Michigan PCAT1 ncRNA AND USES THEREOF
RU2639509C2 (ru) * 2011-06-27 2017-12-21 Эйсай Ар Энд Ди Менеджмент Ко., Лтд. МикроРНК - БИОМАРКЕРЫ, УКАЗЫВАЮЩИЕ НА БОЛЕЗНЬ АЛЬЦГЕЙМЕРА
EP3492606B1 (en) * 2011-08-22 2023-10-04 Exosome Diagnostics, Inc. Urine biomarkers
JP2014003925A (ja) 2012-06-22 2014-01-16 Japanese Foundation For Cancer Research 予後不良の肺小細胞がんの検査方法及び治療手段
WO2017190003A1 (en) * 2016-04-28 2017-11-02 Joslin Diabetes Center, Inc. Compositions and method for treating and preventing end stage renal disease

Also Published As

Publication number Publication date
JP2021502069A (ja) 2021-01-28
US20250154598A1 (en) 2025-05-15
AU2025204881B2 (en) 2025-10-02
WO2019094780A3 (en) 2020-04-02
JP2024009855A (ja) 2024-01-23
EP3707259A4 (en) 2021-08-11
US20250101509A1 (en) 2025-03-27
AU2025204881A1 (en) 2025-07-17
US20200362420A1 (en) 2020-11-19
CA3082391A1 (en) 2019-05-16
JP2026041956A (ja) 2026-03-10
US12398429B2 (en) 2025-08-26
WO2019094780A2 (en) 2019-05-16
JP7549880B2 (ja) 2024-09-12
EP3707259A2 (en) 2020-09-16
CN111344409A (zh) 2020-06-26
US20220325359A1 (en) 2022-10-13
AU2018364987A1 (en) 2020-04-23

Similar Documents

Publication Publication Date Title
MX2020004949A (es) Arn no codificante para la deteccion de cancer.
MX394474B (es) Métodos de pronóstico para cáncer de vejiga sin invasión muscular y antagonistas para usarse en el tratamiento de lo mismo.
MX2017003790A (es) Detección de secuencias diana por percepción de nanoporos de sondas sintéticas.
EP4656740A3 (en) Breast cancer detection kit or device, and detection method
BR112016029634A2 (pt) kit, dispositivo e método para a detecção de câncer de fígado
MX386750B (es) MARCADORES DE METILACIÓN Y DE miARN PARA LA DETECCIÓN DE CÁNCER.
GB2556004A (en) Markers of stroke and stroke severity
BR112016028944A2 (pt) kit ou dispositivo para a detecção de câncer do trato biliar e método de detecção
EA201692157A1 (ru) Синтез двухцепочечных нуклеиновых кислот
MX2014004860A (es) Biomarcadores de cancer de pulmon y usos de los mismos.
MX373957B (es) Un método in vitro para detectar un biomarcador de cáncer en un sujeto.
MX2016012285A (es) Tratamiento de cáncer con antagonista de c-met y correlación de estos con la expresión de hgf.
WO2015149034A3 (en) Gene fusions and gene variants associated with cancer
MX2018014163A (es) Composiciones de nucleotido marcados y metodos para el secuenciamiento de acido nucleico.
WO2015164747A8 (en) Methods for diagnosing celiac disease using circulating cytokines/chemokines
MX2017006075A (es) Biomarcadores para la progresion de enfermedades en melanoma.
WO2015179777A3 (en) Gene expression profiles associated with sub-clinical kidney transplant rejection
ES2548299B2 (es) Firma de microARN como indicador del riesgo de recurrencia temprana en pacientes con cáncer de mama
MX382055B (es) Nuevo anticuerpo igf - 1r y su uso para el diagnóstico del cáncer.
RU2010123021A (ru) Способ диагностики рака молочной железы по уровню рнк интерлейкинов il-8 и/или il-18 в плазме крови
GB2538006A (en) Gene expression profiles associated with sub-clinical kidney transplant rejection
BR112016005413A2 (pt) usos de pelo menos um mirna, kit, métodos de diagnóstico de câncer de mama e métodos para avaliação de risco de metástase
MX2014012842A (es) Oligonucleotidos de candida parapsilosis, metodo de deteccion y kit de los mismos.
WO2017129753A8 (en) Means and methods for staging, typing and treating a cancerous disease
RU2012113807A (ru) Способ оценки функционального состояния эндотелия экспериментальных животных после реконструктивных операций на брюшной аорте