MX2020007971A - Composiciones y metodos para tratar edema pulmonar o inflamacion pulmonar. - Google Patents

Composiciones y metodos para tratar edema pulmonar o inflamacion pulmonar.

Info

Publication number
MX2020007971A
MX2020007971A MX2020007971A MX2020007971A MX2020007971A MX 2020007971 A MX2020007971 A MX 2020007971A MX 2020007971 A MX2020007971 A MX 2020007971A MX 2020007971 A MX2020007971 A MX 2020007971A MX 2020007971 A MX2020007971 A MX 2020007971A
Authority
MX
Mexico
Prior art keywords
lung inflammation
compositions
pulmonary edema
methods
treating pulmonary
Prior art date
Application number
MX2020007971A
Other languages
English (en)
Inventor
David H Ingbar
Timothy P Rich
Robert J Schumacher
Jianxun Lei
Maneesh Bhargava
Original Assignee
Univ Minnesota
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Minnesota filed Critical Univ Minnesota
Publication of MX2020007971A publication Critical patent/MX2020007971A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Otolaryngology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

Una composición farmacéutica para administrarse directamente al tracto pulmonar de un sujeto incluye una sal de triyodotironina y un amortiguador farmacéuticamente aceptable, ajustado a un pH de 5,5-8,5. La composición se puede administrar profiláctica o terapéuticamente a un sujeto para tratar la inflamación pulmonar o el edema pulmonar.
MX2020007971A 2018-01-31 2019-01-31 Composiciones y metodos para tratar edema pulmonar o inflamacion pulmonar. MX2020007971A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862624631P 2018-01-31 2018-01-31
PCT/US2019/016068 WO2019152659A1 (en) 2018-01-31 2019-01-31 Compositions and methods for treating pulmonary edema or lung inflammation

Publications (1)

Publication Number Publication Date
MX2020007971A true MX2020007971A (es) 2020-09-09

Family

ID=67478530

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2020007971A MX2020007971A (es) 2018-01-31 2019-01-31 Composiciones y metodos para tratar edema pulmonar o inflamacion pulmonar.

Country Status (6)

Country Link
US (3) US11458094B2 (es)
EP (1) EP3746067A4 (es)
CN (1) CN112367985A (es)
CA (1) CA3090127A1 (es)
MX (1) MX2020007971A (es)
WO (1) WO2019152659A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112367985A (zh) 2018-01-31 2021-02-12 明尼苏达大学董事会 用于治疗肺水肿或肺炎的组合物和方法
EP3765059A4 (en) * 2018-03-12 2022-01-12 Yale University METHODS OF TREATMENT OR PREVENTION OF ACUTE RESPIRATORY SYNDROME
ES2911528T3 (es) * 2018-07-13 2022-05-19 Aegirbio Ab Biosensor para el diagnóstico de la disfunción tiroidea
US20220265775A1 (en) * 2019-07-31 2022-08-25 Regents Of The University Of Minnesota Compositions and methods for treating pulmonary edema or lung inflammation
MX2022011821A (es) 2020-03-27 2022-10-10 Univ Minnesota Composiciones y metodos para tratar edema pulmonar o inflamacion pulmonar.
WO2021211997A1 (en) * 2020-04-16 2021-10-21 The General Hospital Corporation B cell immunomodulatory therapy for acute respiratory distress syndrome
WO2025245024A1 (en) * 2024-05-20 2025-11-27 Regents Of The University Of Minnesota Compositions comprising liothyronine and methods of making thereof

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6716877B2 (en) * 2001-01-31 2004-04-06 The Arizona Board Of Regents On Behalf Of The University Of Arizona Method to treat chronic heart failure and/or elevated cholesterol levels
US8668926B1 (en) * 2003-09-15 2014-03-11 Shaker A. Mousa Nanoparticle and polymer formulations for thyroid hormone analogs, antagonists, and formulations thereof
US7906140B2 (en) 2004-06-17 2011-03-15 Virun, Inc. Compositions for mucosal delivery of agents
US20090022806A1 (en) 2006-12-22 2009-01-22 Mousa Shaker A Nanoparticle and polymer formulations for thyroid hormone analogs, antagonists and formulations and uses thereof
US8309080B2 (en) 2007-12-06 2012-11-13 Naidu Lp Metallo-protein and tocotrienol (MP-T3) compositions and uses thereof
US9206482B2 (en) 2009-04-29 2015-12-08 Genomedx Biosciences Inc. Systems and methods for expression-based classification of thyroid tissue
WO2010148007A2 (en) 2009-06-17 2010-12-23 Ordway Research Institute, Inc. Nanoparticle and polymer formulations for thyroid hormone, analogs, antagonists, and formulations and uses thereof
CA2780645C (en) * 2009-11-18 2018-01-16 Nektar Therapeutics Salt form of a multi-arm polymer-drug conjugate
WO2015140792A1 (en) 2014-03-16 2015-09-24 Hadasit Medical Research Services And Development Ltd. Type iii deiodinase inhibitors and uses thereof
US9913819B2 (en) * 2014-06-12 2018-03-13 Yale University Methods of treating or preventing fibrotic lung diseases
CN112367985A (zh) 2018-01-31 2021-02-12 明尼苏达大学董事会 用于治疗肺水肿或肺炎的组合物和方法
EP3765059A4 (en) 2018-03-12 2022-01-12 Yale University METHODS OF TREATMENT OR PREVENTION OF ACUTE RESPIRATORY SYNDROME
US20220265775A1 (en) 2019-07-31 2022-08-25 Regents Of The University Of Minnesota Compositions and methods for treating pulmonary edema or lung inflammation

Also Published As

Publication number Publication date
US20210113462A1 (en) 2021-04-22
CN112367985A (zh) 2021-02-12
EP3746067A1 (en) 2020-12-09
EP3746067A4 (en) 2021-11-10
CA3090127A1 (en) 2019-08-08
US11458094B2 (en) 2022-10-04
US20230050861A1 (en) 2023-02-16
US20240350406A1 (en) 2024-10-24
WO2019152659A1 (en) 2019-08-08
US11883528B2 (en) 2024-01-30

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