MX2020009703A - Tratamiento de hipertension portal y restauracion de la funcion hepatica usando fenilacetato de l-ornitina. - Google Patents

Tratamiento de hipertension portal y restauracion de la funcion hepatica usando fenilacetato de l-ornitina.

Info

Publication number
MX2020009703A
MX2020009703A MX2020009703A MX2020009703A MX2020009703A MX 2020009703 A MX2020009703 A MX 2020009703A MX 2020009703 A MX2020009703 A MX 2020009703A MX 2020009703 A MX2020009703 A MX 2020009703A MX 2020009703 A MX2020009703 A MX 2020009703A
Authority
MX
Mexico
Prior art keywords
liver function
restoration
treatment
portal hypertension
ornithine phenylacetate
Prior art date
Application number
MX2020009703A
Other languages
English (en)
Inventor
Keith Anderson
Rajiv Jalan
Original Assignee
Ucl Business Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ucl Business Plc filed Critical Ucl Business Plc
Publication of MX2020009703A publication Critical patent/MX2020009703A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

La presente invención se relaciona con métodos de tratamiento y/o prevención de hipertensión portal y/o restauración de la función hepática usando fenilacetato de L-ornitina.
MX2020009703A 2009-06-08 2011-12-07 Tratamiento de hipertension portal y restauracion de la funcion hepatica usando fenilacetato de l-ornitina. MX2020009703A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18515809P 2009-06-08 2009-06-08
US24074809P 2009-09-09 2009-09-09
US29637710P 2010-01-19 2010-01-19

Publications (1)

Publication Number Publication Date
MX2020009703A true MX2020009703A (es) 2020-10-07

Family

ID=43309444

Family Applications (3)

Application Number Title Priority Date Filing Date
MX2015012475A MX375116B (es) 2009-06-08 2010-06-08 Tratamiento de hipertension portal y restauracion de la funcion hepatica usando fenilacetato de l-ornitina.
MX2011013129A MX2011013129A (es) 2009-06-08 2010-06-08 Tratamiento de hipertension portal y restauracion de la funcion hepatica usando fenilacetato de l-ornitina.
MX2020009703A MX2020009703A (es) 2009-06-08 2011-12-07 Tratamiento de hipertension portal y restauracion de la funcion hepatica usando fenilacetato de l-ornitina.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
MX2015012475A MX375116B (es) 2009-06-08 2010-06-08 Tratamiento de hipertension portal y restauracion de la funcion hepatica usando fenilacetato de l-ornitina.
MX2011013129A MX2011013129A (es) 2009-06-08 2010-06-08 Tratamiento de hipertension portal y restauracion de la funcion hepatica usando fenilacetato de l-ornitina.

Country Status (18)

Country Link
US (2) US20120157526A1 (es)
EP (3) EP2440200B8 (es)
JP (3) JP5749255B2 (es)
KR (2) KR20170026672A (es)
CN (2) CN102625699B (es)
AU (1) AU2010258888B2 (es)
BR (1) BRPI1012956A8 (es)
CA (2) CA2764587C (es)
DK (2) DK2440200T3 (es)
EA (2) EA025735B1 (es)
ES (2) ES2728948T3 (es)
IL (2) IL216811A (es)
MX (3) MX375116B (es)
NZ (2) NZ615091A (es)
PL (1) PL2440200T3 (es)
SG (1) SG176675A1 (es)
WO (1) WO2010144498A2 (es)
ZA (1) ZA201108988B (es)

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EP2440200B8 (en) 2009-06-08 2014-10-15 UCL Business PLC Treatment of portal hypertension using l-ornithine phenylacetate
EP2625162B1 (en) 2010-10-06 2019-03-13 Ocera Therapeutics, Inc. Methods of making l-ornithine phenyl acetate
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JP6990170B2 (ja) * 2015-08-18 2022-01-12 オセラ セラピューティクス， インコーポレイテッド Ｌ－オルニチンをフェニルアセテートおよびフェニルブチレートのうちの少なくとも１つと組み合わせて用いる筋肉喪失の治療および予防
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SG11201802987UA (en) * 2015-11-13 2018-05-30 Ocera Therapeutics Inc Formulation of l-ornithine phenylacetate
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KR102237526B1 (ko) * 2019-11-07 2021-04-07 한국식품연구원 오르니틴 생성능이 우수한 락토바실러스 브레비스 wikim47를 이용한 마늘 발효 조성물
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Also Published As

Publication number Publication date
ZA201108988B (en) 2015-04-29
BRPI1012956A8 (pt) 2021-11-03
CA2997484C (en) 2020-05-12
EP2440200A2 (en) 2012-04-18
WO2010144498A9 (en) 2011-04-28
JP2017066153A (ja) 2017-04-06
US20120157526A1 (en) 2012-06-21
EP2440200B8 (en) 2014-10-15
ES2728948T3 (es) 2019-10-29
JP6250588B2 (ja) 2017-12-20
EA025735B1 (ru) 2017-01-30
HK1203419A1 (en) 2015-10-30
CN102625699A (zh) 2012-08-01
EA201691430A1 (ru) 2017-02-28
JP5749255B2 (ja) 2015-07-15
KR101715008B1 (ko) 2017-03-22
US11266620B2 (en) 2022-03-08
IL216811A0 (en) 2012-02-29
MX375116B (es) 2025-03-06
IL216811A (en) 2016-11-30
ES2517340T3 (es) 2014-11-03
JP2015163635A (ja) 2015-09-10
BRPI1012956A2 (pt) 2017-06-06
MX2011013129A (es) 2012-03-14
CA2764587C (en) 2018-04-24
WO2010144498A2 (en) 2010-12-16
KR20120047891A (ko) 2012-05-14
JP2012529523A (ja) 2012-11-22
PL2440200T3 (pl) 2015-08-31
AU2010258888B2 (en) 2014-08-07
CN102625699B (zh) 2014-08-20
SG176675A1 (en) 2012-01-30
KR20170026672A (ko) 2017-03-08
EP3517110A1 (en) 2019-07-31
NZ596916A (en) 2013-09-27
US20180161293A1 (en) 2018-06-14
EP2440200A4 (en) 2012-11-28
CA2764587A1 (en) 2010-12-16
EA201171396A1 (ru) 2012-10-30
IL248696B (en) 2020-05-31
JP6527497B2 (ja) 2019-06-05
IL248696A0 (en) 2016-12-29
CN104434894A (zh) 2015-03-25
HK1174264A1 (en) 2013-06-07
EP2440200B1 (en) 2014-08-27
DK2799067T3 (da) 2019-06-03
AU2010258888A1 (en) 2012-02-02
NZ615091A (en) 2015-03-27
EP2799067A1 (en) 2014-11-05
EP2799067B1 (en) 2019-04-03
DK2440200T3 (en) 2014-12-08
CA2997484A1 (en) 2010-12-16

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