MX2020009842A - Uso de conjugados de anticuerpo-farmaco que comprenden agentes interruptores de tubulina para tratar tumor solido. - Google Patents

Uso de conjugados de anticuerpo-farmaco que comprenden agentes interruptores de tubulina para tratar tumor solido.

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Publication number
MX2020009842A
MX2020009842A MX2020009842A MX2020009842A MX2020009842A MX 2020009842 A MX2020009842 A MX 2020009842A MX 2020009842 A MX2020009842 A MX 2020009842A MX 2020009842 A MX2020009842 A MX 2020009842A MX 2020009842 A MX2020009842 A MX 2020009842A
Authority
MX
Mexico
Prior art keywords
solid tumor
drug conjugates
antibody drug
disrupting agents
treat solid
Prior art date
Application number
MX2020009842A
Other languages
English (en)
Inventor
Anthony Toa Cao
Shyra Jane Gardai
Original Assignee
Seattle Genetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seattle Genetics Inc filed Critical Seattle Genetics Inc
Publication of MX2020009842A publication Critical patent/MX2020009842A/es

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    • C07K16/2896—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
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    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3076—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties
    • C07K16/3084—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties against tumour-associated gangliosides
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    • C07K16/32—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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Abstract

La presente descripción se refiere, en general, a métodos para tratar tumores sólidos que comprenden administrar un conjugado de fármaco-ligador-anticuerpo, en donde el fármaco es un agente interruptor de tubulina.
MX2020009842A 2018-03-23 2019-03-22 Uso de conjugados de anticuerpo-farmaco que comprenden agentes interruptores de tubulina para tratar tumor solido. MX2020009842A (es)

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US201862658276P 2018-04-16 2018-04-16
PCT/US2019/023516 WO2019183438A1 (en) 2018-03-23 2019-03-22 Use of antibody drug conjugates comprising tubulin disrupting agents to treat solid tumor

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KR20200135841A (ko) 2020-12-03
CA3093731A1 (en) 2019-09-26
BR112020018948A2 (pt) 2021-01-05
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