MX2022014108A - Variantes de transglutaminasa y aplicaciones de uso de las mismas. - Google Patents

Variantes de transglutaminasa y aplicaciones de uso de las mismas.

Info

Publication number
MX2022014108A
MX2022014108A MX2022014108A MX2022014108A MX2022014108A MX 2022014108 A MX2022014108 A MX 2022014108A MX 2022014108 A MX2022014108 A MX 2022014108A MX 2022014108 A MX2022014108 A MX 2022014108A MX 2022014108 A MX2022014108 A MX 2022014108A
Authority
MX
Mexico
Prior art keywords
variants
transglutaminase
proteins
methods
functional ingredients
Prior art date
Application number
MX2022014108A
Other languages
English (en)
Inventor
Erika M Milczek
William Shindel
Kamil S Gedeon
Simone A Costa
Original Assignee
Curie Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Curie Co Inc filed Critical Curie Co Inc
Publication of MX2022014108A publication Critical patent/MX2022014108A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1022—Transferases (2.) transferring aldehyde or ketonic groups (2.2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/50—Isolated enzymes; Isolated proteins
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
    • A01P1/00—Disinfectants; Antimicrobial compounds or mixtures thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/45—Transferases (2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/35—Ketones, e.g. benzophenone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/41—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/41—Amines
    • A61K8/415—Aminophenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A61K8/445—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof aromatic, i.e. the carboxylic acid directly linked to the aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
    • A61K8/466—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur containing sulfonic acid derivatives; Salts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66—Enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/89—Polysiloxanes
    • A61K8/891—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
    • C12N9/0022—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/02—Aminoacyltransferases (2.3.2)
    • C12Y203/02013—Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/10—General cosmetic use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/26—Optical properties
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Environmental Sciences (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Emergency Medicine (AREA)
  • Dentistry (AREA)
  • Virology (AREA)
  • Agronomy & Crop Science (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Cosmetics (AREA)

Abstract

Variantes de la enzima transglutaminasa de Streptomyces mobaraensis. Las variantes descritas presentan una actividad enzimática aumentada al menos aproximadamente 2 veces frente a la enzima de tipo silvestre. Se proporcionan métodos y composiciones para aplicaciones biocidas de uso y para unir covalentemente pequeñas moléculas orgánicas a una proteína o material de interés. Se proporcionan métodos para aumentar la vida útil de productos, tales como productos para el cuidado personal, para el hogar e industriales, mediante la incorporación de una cantidad efectiva de las enzimas variantes descritas en el producto. Las variantes de transglutaminasa también se pueden usar para unir covalentemente ingredientes funcionales, tales como moléculas bloqueadoras de UV, colorantes o pigmentos a proteínas. Las enzimas transglutaminasa y los ingredientes funcionales pueden incorporarse en una formulación cosmética para modificar proteínas de la piel, el cabello o las uñas o proteínas derivadas de la piel, tales como colágeno, queratina y/o elastina.
MX2022014108A 2020-05-13 2021-05-13 Variantes de transglutaminasa y aplicaciones de uso de las mismas. MX2022014108A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063024398P 2020-05-13 2020-05-13
US202063074288P 2020-09-03 2020-09-03
PCT/US2021/032217 WO2021231705A1 (en) 2020-05-13 2021-05-13 Transglutaminase variants and applications of use thereof

Publications (1)

Publication Number Publication Date
MX2022014108A true MX2022014108A (es) 2023-02-23

Family

ID=78525029

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022014108A MX2022014108A (es) 2020-05-13 2021-05-13 Variantes de transglutaminasa y aplicaciones de uso de las mismas.

Country Status (9)

Country Link
US (3) US20230203457A1 (es)
EP (1) EP4150062A4 (es)
JP (2) JP2023526199A (es)
KR (2) KR20230010681A (es)
CN (2) CN115605588A (es)
BR (1) BR112022021955A2 (es)
CA (1) CA3181352A1 (es)
MX (1) MX2022014108A (es)
WO (1) WO2021231705A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20250304927A1 (en) 2022-05-20 2025-10-02 Curie Co. Inc. Pro-peptide variants for modulating activity of transglutaminases
WO2024243088A1 (en) 2023-05-19 2024-11-28 Curie Co. Inc. Transglutaminases and uses thereof
WO2025185891A1 (en) * 2024-03-08 2025-09-12 Unilever Ip Holdings B.V. A cosmetic composition comprising oligo-, tetra- and hexapeptides

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5490980A (en) * 1994-09-28 1996-02-13 Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. Covalent bonding of active agents to skin, hair or nails
US6919076B1 (en) * 1998-01-20 2005-07-19 Pericor Science, Inc. Conjugates of agents and transglutaminase substrate linking molecules
DE60137510D1 (de) * 2000-07-19 2009-03-12 Novozymes As Zellwandabbauende enzymvarianten
BR0113304A (pt) * 2000-08-17 2004-01-06 Ajinomoto Kk Método para planejar e preparar uma transglutaminase mutante, mtg mutante transglutaminase mutante, gene, dna recombinante, microorganismos, método para produzir uma mtg mutante ou uma transglutaminase mutante, e, cristais de mtg monoclìnicos
US8771649B2 (en) * 2003-05-30 2014-07-08 Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno Inducible release vehicles
US20050268405A1 (en) * 2004-05-28 2005-12-08 Gaelle Brun Composition for dyeing keratin fibers, comprising at least one pigment and polymers capable of reacting with each other to form covalent bonds
US9056899B2 (en) * 2008-01-10 2015-06-16 Trustees Of Boston University Engineered bacteriophages as adjuvants for antimicrobial agents and compositions and methods of use thereof
WO2010101256A1 (ja) * 2009-03-06 2010-09-10 味の素株式会社 放線菌由来の耐熱性トランスグルタミナーゼ
EP2456865A1 (en) * 2009-07-24 2012-05-30 Novozymes A/S Carbohydrate oxidases
FI126442B (en) * 2011-11-01 2016-12-15 Valio Oy Liquid enzyme preparation and process for its preparation
US20150175980A1 (en) * 2012-06-08 2015-06-25 Concordia University Novel cell wall deconstruction enzymes of scytalidium thermophilum, myriococcum thermophilum, and aureobasidium pullulans, and uses thereof
EP2913045B1 (en) * 2012-10-17 2019-04-10 Ajinomoto Co., Inc. Cosmetic composition
JP2018531935A (ja) * 2015-10-02 2018-11-01 ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ 抗体を結合させるためのトランスグルタミナーゼバリアント
WO2017059160A1 (en) * 2015-10-02 2017-04-06 Bristol-Myers Squibb Company Transglutaminase variants having increased specific activity
WO2019107288A1 (ja) * 2017-11-30 2019-06-06 天野エンザイム株式会社 改変型トランスグルタミナーゼ

Also Published As

Publication number Publication date
BR112022021955A2 (pt) 2022-12-13
CA3181352A1 (en) 2021-11-18
US20230203457A1 (en) 2023-06-29
CN118475335A (zh) 2024-08-09
JP2024543376A (ja) 2024-11-21
WO2021231705A9 (en) 2022-03-03
KR20230010681A (ko) 2023-01-19
US20220160601A1 (en) 2022-05-26
US20250017834A1 (en) 2025-01-16
WO2021231705A1 (en) 2021-11-18
CN115605588A (zh) 2023-01-13
JP2023526199A (ja) 2023-06-21
EP4150062A1 (en) 2023-03-22
KR20240109259A (ko) 2024-07-10
EP4150062A4 (en) 2024-08-14

Similar Documents

Publication Publication Date Title
RU2006145670A (ru) Кератинсвязывающие полипептиды
CN103421872B (zh) 一种鳄鱼皮胶原蛋白肽的制备方法及其用途
BR112022021955A2 (pt) Variantes de transglutaminase e aplicações de uso das mesmas
US10987295B2 (en) Method of facilitating the bindings between keratinocytes
ATE254448T1 (de) Kosmetische oder dermatologische zusammensetzung, enthaltend zumindest ein natürliches oder rekombinantes seidenprotein von arachniden oder ein analoges protein
JP6729624B2 (ja) 化粧料組成物
BRPI0604706A (pt) composição cosmética e processo de tratamento cosmético das matérias queratìnicas
JP6917301B2 (ja) トリュフの水性抽出物およびその化粧用組成物
Baby et al. Dermocosmetic applications of microalgal pigments
KR102050545B1 (ko) 미역귀 추출물, 감태 추출물 및 글리코사미노글리칸을 포함하는 항노화 기능성 화장료 조성물
Harinisri Ram et al. Inventive applications of marine resources in cosmetic production: A review
FR2935378A1 (fr) Utiisation de n-acyl aminoacides comme principes actifs cosmetiques et pharmaceutiques, capables de reduire l'etat inflammatoire des fibroblastes replicatifs senescents issus du derme humain adulte; compositions cosmetiques anti-age
CN106999400B (zh) 包含Sirt6活化剂和DNA修复酶的组合物
ATE493966T1 (de) Mittel zur förderung der hautkollagenproduktion
JP5878751B2 (ja) 毛髪化粧料
US20100008897A1 (en) Composition for providing a benefit to a keratin-containing substrate
İstanbulluoğlu et al. Kozmetiklerde Kullanılan Biyoteknolojik Etkin ve Yardımcı Maddeler
US20120220523A1 (en) Use of a corn peptidi hydrolyzate as an active agent stimulating hair growth
KR100554938B1 (ko) 3-분자 복합체를 기초로 한 피부관리용 화장품
KR101886123B1 (ko) 주름 개선용 펩타이드, 및 이의 용도
Sergeeva et al. Biomass of phototrophic microorganisms as a source of active components for cosmetics
JP5973158B2 (ja) 毛髪化粧料
Vandamme et al. Personal care products via fermentation and biocatalysis processes
Germán-Báez et al. Microalgae as a Potential Source of Cosmeceutical Products with Anti-aging Properties
Chotani et al. Manufacturing ingredients and products by fermentation