MX2025009673A - Composiciones para la terapia con celulas t con receptores de antigeno quimerico y usos de las mismas - Google Patents
Composiciones para la terapia con celulas t con receptores de antigeno quimerico y usos de las mismasInfo
- Publication number
- MX2025009673A MX2025009673A MX2025009673A MX2025009673A MX2025009673A MX 2025009673 A MX2025009673 A MX 2025009673A MX 2025009673 A MX2025009673 A MX 2025009673A MX 2025009673 A MX2025009673 A MX 2025009673A MX 2025009673 A MX2025009673 A MX 2025009673A
- Authority
- MX
- Mexico
- Prior art keywords
- compositions
- antigen receptor
- chimeric antigen
- cell therapy
- lipid
- Prior art date
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
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- A61K47/544—Phospholipids
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- A61K39/0011—Cancer antigens
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- A61K39/001103—Receptors for growth factors
- A61K39/001104—Epidermal growth factor receptors [EGFR]
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- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
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- C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/289—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD45
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3053—Skin, nerves, brain
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- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
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- C07K2319/00—Fusion polypeptide
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- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
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- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
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- C07K2319/00—Fusion polypeptide
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- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
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Abstract
La descripción presenta conjugados de ligando anfifílico que comprenden un ligando del receptor de antígeno quimérico (CAR) y un lípido. La descripción también presenta composiciones y métodos para usar los mismos, por ejemplo, para estimular la proliferación de células que expresan CAR.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762560588P | 2017-09-19 | 2017-09-19 | |
| PCT/US2018/051764 WO2019060425A1 (en) | 2017-09-19 | 2018-09-19 | COMPOSITIONS FOR CHIMERIC ANTIGENIC RECEPTOR T CELL THERAPY AND USES THEREOF |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2025009673A true MX2025009673A (es) | 2025-09-02 |
Family
ID=64564947
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2025009673A MX2025009673A (es) | 2017-09-19 | 2018-09-19 | Composiciones para la terapia con celulas t con receptores de antigeno quimerico y usos de las mismas |
| MX2020002901A MX2020002901A (es) | 2017-09-19 | 2018-09-19 | Composiciones para la terapia con celulas t con receptores de antigeno quimerico y usos de las mismas. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2020002901A MX2020002901A (es) | 2017-09-19 | 2018-09-19 | Composiciones para la terapia con celulas t con receptores de antigeno quimerico y usos de las mismas. |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20200230221A1 (es) |
| EP (1) | EP3684408A1 (es) |
| JP (2) | JP7654240B2 (es) |
| KR (2) | KR20260026092A (es) |
| CN (1) | CN111148533A (es) |
| AU (1) | AU2018336791B2 (es) |
| CA (1) | CA3076337A1 (es) |
| MX (2) | MX2025009673A (es) |
| WO (1) | WO2019060425A1 (es) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10704021B2 (en) | 2012-03-15 | 2020-07-07 | Flodesign Sonics, Inc. | Acoustic perfusion devices |
| JP6375289B2 (ja) | 2012-04-05 | 2018-08-15 | マサチューセッツ インスティテュート オブ テクノロジー | 免疫刺激組成物およびその使用方法 |
| CN105939767B (zh) | 2014-01-08 | 2018-04-06 | 弗洛设计声能学公司 | 具有双声电泳腔的声电泳装置 |
| US11708572B2 (en) | 2015-04-29 | 2023-07-25 | Flodesign Sonics, Inc. | Acoustic cell separation techniques and processes |
| US11377651B2 (en) | 2016-10-19 | 2022-07-05 | Flodesign Sonics, Inc. | Cell therapy processes utilizing acoustophoresis |
| CN114900773A (zh) | 2017-12-14 | 2022-08-12 | 弗洛设计声能学公司 | 声泳系统及其操作方法、控制声换能器及声学系统的方法 |
| AU2019218729B2 (en) | 2018-02-06 | 2025-12-04 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Fluorescein-specific CARs exhibiting optimal T cell function against FL-PLE labelled tumors |
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-
2018
- 2018-09-19 CA CA3076337A patent/CA3076337A1/en active Pending
- 2018-09-19 JP JP2020515969A patent/JP7654240B2/ja active Active
- 2018-09-19 MX MX2025009673A patent/MX2025009673A/es unknown
- 2018-09-19 CN CN201880061030.XA patent/CN111148533A/zh active Pending
- 2018-09-19 EP EP18811951.5A patent/EP3684408A1/en active Pending
- 2018-09-19 WO PCT/US2018/051764 patent/WO2019060425A1/en not_active Ceased
- 2018-09-19 US US16/644,893 patent/US20200230221A1/en not_active Abandoned
- 2018-09-19 MX MX2020002901A patent/MX2020002901A/es unknown
- 2018-09-19 KR KR1020267003190A patent/KR20260026092A/ko active Pending
- 2018-09-19 AU AU2018336791A patent/AU2018336791B2/en active Active
- 2018-09-19 KR KR1020207010759A patent/KR20200055037A/ko not_active Ceased
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2023
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2025
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Also Published As
| Publication number | Publication date |
|---|---|
| CA3076337A1 (en) | 2019-03-28 |
| KR20260026092A (ko) | 2026-02-25 |
| EP3684408A1 (en) | 2020-07-29 |
| WO2019060425A1 (en) | 2019-03-28 |
| AU2018336791A1 (en) | 2020-03-12 |
| WO2019060425A8 (en) | 2019-06-06 |
| RU2020113680A (ru) | 2021-10-20 |
| MX2020002901A (es) | 2020-07-22 |
| JP7654240B2 (ja) | 2025-04-01 |
| KR20200055037A (ko) | 2020-05-20 |
| US20240082373A1 (en) | 2024-03-14 |
| JP2025036704A (ja) | 2025-03-14 |
| US20200230221A1 (en) | 2020-07-23 |
| RU2020113680A3 (es) | 2021-12-29 |
| CN111148533A (zh) | 2020-05-12 |
| AU2018336791B2 (en) | 2025-08-21 |
| JP2020535128A (ja) | 2020-12-03 |
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