MX344112B - Method and device for treating blood cholesterol disorders. - Google Patents

Method and device for treating blood cholesterol disorders.

Info

Publication number
MX344112B
MX344112B MX2013002681A MX2013002681A MX344112B MX 344112 B MX344112 B MX 344112B MX 2013002681 A MX2013002681 A MX 2013002681A MX 2013002681 A MX2013002681 A MX 2013002681A MX 344112 B MX344112 B MX 344112B
Authority
MX
Mexico
Prior art keywords
abnormal
levels
blood cholesterol
treatment
treating blood
Prior art date
Application number
MX2013002681A
Other languages
Spanish (es)
Other versions
MX2013002681A (en
Inventor
Grifols Lucas Victor
Grifols Roura Victor
Original Assignee
Grifols Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Grifols Sa filed Critical Grifols Sa
Publication of MX2013002681A publication Critical patent/MX2013002681A/en
Publication of MX344112B publication Critical patent/MX344112B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3496—Plasmapheresis; Leucopheresis; Lymphopheresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/38—Removing constituents from donor blood and storing or returning remainder to body, e.g. for transfusion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/16—Blood plasma; Blood serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/75—General characteristics of the apparatus with filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/12—Blood circulatory system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Anesthesiology (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Obesity (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • External Artificial Organs (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

A method and device for treating cholesterol disorders includes administering at least one treatment regime including two or more rounds of plasmapheresis to a patient having abnormal total cholesterol, abnormal LDL levels and/or abnormal HDL levels prior to treatment. Treatment according to the method results in decreased LDL levels in patients having abnormal LDL levels and increased HDL levels in patients having abnormal HDL levels. Each subsequent round of plasmapheresis is conducted weekly, but no more than twice per week.
MX2013002681A 2012-03-12 2013-03-08 Method and device for treating blood cholesterol disorders. MX344112B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13/418,123 US10624924B2 (en) 2012-03-12 2012-03-12 Method and device for treating blood cholesterol disorders

Publications (2)

Publication Number Publication Date
MX2013002681A MX2013002681A (en) 2013-09-12
MX344112B true MX344112B (en) 2016-11-30

Family

ID=47891413

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013002681A MX344112B (en) 2012-03-12 2013-03-08 Method and device for treating blood cholesterol disorders.

Country Status (23)

Country Link
US (1) US10624924B2 (en)
EP (1) EP2638918B1 (en)
JP (1) JP6218401B2 (en)
KR (2) KR20130105452A (en)
CN (2) CN107754038A (en)
AR (1) AR090295A1 (en)
AU (1) AU2013201550B2 (en)
BR (1) BR102013005877B1 (en)
CA (1) CA2809012C (en)
CL (1) CL2013000667A1 (en)
ES (1) ES2598241T3 (en)
HU (1) HUE029681T2 (en)
IL (1) IL225129A (en)
MX (1) MX344112B (en)
MY (1) MY169320A (en)
NZ (1) NZ608133A (en)
PL (1) PL2638918T3 (en)
PT (1) PT2638918T (en)
RU (1) RU2625774C2 (en)
SG (1) SG193729A1 (en)
TW (1) TWI554275B (en)
UY (1) UY34667A (en)
ZA (1) ZA201301815B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10624924B2 (en) 2012-03-12 2020-04-21 Grifols, S.A. Method and device for treating blood cholesterol disorders
AU2015201496B2 (en) * 2014-06-03 2019-10-31 Grifols Worldwide Operations Limited Use of plasmapheresis to treat blood pressure disorders
AU2023279725A1 (en) * 2022-05-31 2025-01-16 Circulate Health, Inc. Compositions and methods for plasmapheresis

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4374731A (en) 1980-03-06 1983-02-22 Baxter Travenol Laboratories, Inc. Method and apparatus for obtaining a desired rate of plasma collection from a membrane plasmapheresis filter
US4350156A (en) 1980-05-29 1982-09-21 Japan Foundation For Artificial Organs Method and apparatus for on-line filtration removal of macromolecules from a physiological fluid
US4540401A (en) * 1983-02-22 1985-09-10 Applied Immune Sciences, Inc. In vivo therapeutic apheresis using lipid vesicles
AU4409285A (en) 1984-06-29 1986-01-24 Hemascience Laboratories Inc. Blood extraction and reinfusion flow control system and method
US5258149A (en) 1990-11-27 1993-11-02 W. R. Grace & Co.-Conn. Process of making a membrane for high efficiency removal of low density lipoprotein-cholesterol from whole blood
CA2095424A1 (en) 1992-05-14 1993-11-15 Marc Ellous Parham Microporous polysulfone support suitable for removal of low density lipoprotein-cholesterol
JPH06254152A (en) * 1993-03-03 1994-09-13 Terumo Corp Blood plasma changing device
JPH0788179A (en) * 1993-09-22 1995-04-04 Terumo Corp Blood plasma exchange device
RU2113240C1 (en) 1995-05-05 1998-06-20 Акционерное общество закрытого типа "Оптика" Method and device for carrying out membrane plasmapheresis under single needle scheme
WO1996037602A1 (en) 1995-05-26 1996-11-28 Diacrin, Inc. Porcine hepatocytes for use in treatment of disorders characterized by insufficient liver function
WO1997015380A1 (en) 1995-10-23 1997-05-01 Hemasure, Inc. Extra-lumenal crossflow plasmapheresis devices
FR2747591B1 (en) 1996-04-19 1998-05-22 Hospal Ind MEDICAL DEVICE FOR EXTRACORPOREAL BLOOD OR PLASMA TREATMENT AND METHODS OF MAKING THE SAME
CA2257474A1 (en) * 1996-06-07 1997-12-11 Eli Lilly And Company Ob protein binding protein
US6627151B1 (en) 1997-06-13 2003-09-30 Helmut Borberg Method for treatment diseases associated with a deterioration of the macrocirculation, microcirculation and organ perfusion
RU2153168C2 (en) * 1997-11-25 2000-07-20 Научно-исследовательский институт кардиологии Method for determining indications to administering plasmapheresis in treating the cases of angina pectoris
DE19821534C1 (en) 1998-05-14 1999-08-19 Braun Melsungen Ag Blood cleaning machine
WO2000038760A2 (en) * 1998-12-29 2000-07-06 Occulogix Corporation Rheological treatment methods and related apheresis systems
JP4903311B2 (en) 1999-04-30 2012-03-28 チルドレンズ ホスピタル メディカル センター Hematological filtration system and method based on monitored patient parameters, hemofiltration monitoring and control apparatus and adaptive control of blood filtration pump
RU2195321C2 (en) 2000-11-16 2002-12-27 Государственный научно-клинический центр охраны здоровья шахтеров Cerebral atherosclerosis treatment method
US6991727B2 (en) 2001-06-25 2006-01-31 Lipid Sciences, Inc. Hollow fiber contactor systems for removal of lipids from fluids
US6982038B2 (en) * 2002-06-14 2006-01-03 Medtronic, Inc. Centrifuge system utilizing disposable components and automated processing of blood to collect platelet rich plasma
AU2003251567A1 (en) 2002-06-19 2004-01-06 The Board Of Regents Of The University Of Texas System Dialysis system for treatment of vulnerable patients and methods of use
AU2003303198A1 (en) 2002-12-19 2004-07-14 New York University Method for treating amyloid disease
JP2007527387A (en) * 2003-07-03 2007-09-27 リピッド サイエンシーズ，インコーポレイテッド Method and apparatus for producing particle derivatives of HDL with reduced lipid content
US7393826B2 (en) 2003-07-03 2008-07-01 Lipid Sciences, Inc. Methods and apparatus for creating particle derivatives of HDL with reduced lipid content
US20100316730A1 (en) * 2003-07-31 2010-12-16 Latino Joseph S Treatment of cardiovascular diseases with ozone
US20050051497A1 (en) 2003-07-31 2005-03-10 Latino Joseph S. Viral inactivation using ozone
US8038638B2 (en) 2004-02-23 2011-10-18 Hemolife Medical, Inc. Plasma detoxification and volume control system and methods of use
DE102004054747A1 (en) 2004-11-12 2006-05-24 Fresenius Medical Care Deutschland Gmbh Method and device for depleting at least one component of a fluid medium
BRPI0614083A2 (en) 2005-08-05 2011-03-09 Nat Quality Care Inc dual channel pulsating pump and fully portable artificial kidney device (rap)
RU2310478C1 (en) 2006-05-03 2007-11-20 Александр Георгиевич Рожков Method for treating atherosclerosis
GB0621452D0 (en) 2006-10-27 2006-12-06 Ucl Business Plc Therapy for liver disease
CN100500229C (en) 2006-12-29 2009-06-17 上海达华医疗器械有限公司 Multifunctional in-vitro blood therapeutic instrument
FR2911417B1 (en) 2007-01-17 2009-02-27 Gambro Lundia Ab MONITORING THE VASCULAR ACCESS OF A PATIENT SUBJECTED TO SUCCESSIVE EXTRACORPOREAL BLOOD TREATMENT SESSIONS
US20120165685A1 (en) 2010-12-22 2012-06-28 Weasler Marc N Plasmapheresis donor display and method of use
CN201006071Y (en) 2007-02-13 2008-01-16 沈建华 Intelligent transfusion pump
US8409441B2 (en) 2007-02-27 2013-04-02 Deka Products Limited Partnership Blood treatment systems and methods
BRPI0923192A2 (en) 2008-12-19 2017-03-28 Anthera Pharmaceuticals Inc treatment of major adverse cardiac events and acute coronary syndrome using combination therapies of secretory phospholipase a2 (spla2) inhibitors or spla2 inhibitor
WO2011015380A1 (en) 2009-08-05 2011-02-10 Celltrend Gmbh Method for prognosis of pulmonary arterial hypertension by detecting anti-par2-antibodies
CN102712503A (en) 2009-10-08 2012-10-03 大冢制药株式会社 An immunoactivation blood perfusion filter for the treatment of malignant tumors
WO2011080191A1 (en) 2009-12-28 2011-07-07 Gambro Lundia Ab Monitoring blood pressure
CA3012773C (en) 2010-10-19 2022-05-03 L&F Research Llc Assays, methods and kits for predicting renal disease and personalized treatment strategies
JP6169495B2 (en) 2011-02-07 2017-07-26 アガミン・エルエルシー Methods and systems for treating or preventing pregnancy-related hypertensive disorders
US10624924B2 (en) 2012-03-12 2020-04-21 Grifols, S.A. Method and device for treating blood cholesterol disorders

Also Published As

Publication number Publication date
ES2598241T3 (en) 2017-01-26
CA2809012C (en) 2020-04-14
CN103301520A (en) 2013-09-18
CL2013000667A1 (en) 2013-07-12
JP6218401B2 (en) 2017-10-25
CN107754038A (en) 2018-03-06
MX2013002681A (en) 2013-09-12
US10624924B2 (en) 2020-04-21
AU2013201550B2 (en) 2015-07-02
PL2638918T3 (en) 2017-01-31
UY34667A (en) 2013-10-31
EP2638918B1 (en) 2016-08-31
MY169320A (en) 2019-03-21
BR102013005877A2 (en) 2017-07-11
HUE029681T2 (en) 2017-02-28
US20130236559A1 (en) 2013-09-12
RU2013110503A (en) 2014-09-20
IL225129A0 (en) 2013-06-27
RU2625774C2 (en) 2017-07-18
TW201340973A (en) 2013-10-16
KR101908899B1 (en) 2018-10-16
NZ608133A (en) 2014-09-26
CA2809012A1 (en) 2013-09-12
AU2013201550A1 (en) 2013-09-26
PT2638918T (en) 2016-10-24
BR102013005877B1 (en) 2021-10-26
EP2638918A1 (en) 2013-09-18
KR20130105452A (en) 2013-09-25
AR090295A1 (en) 2014-11-05
HK1185791A1 (en) 2014-02-28
TWI554275B (en) 2016-10-21
IL225129A (en) 2017-02-28
ZA201301815B (en) 2013-11-27
SG193729A1 (en) 2013-10-30
KR20180074646A (en) 2018-07-03
JP2013188475A (en) 2013-09-26

Similar Documents

Publication Publication Date Title
PH12017502154A1 (en) Methods for conditioning patients for t cell therapy
MX2016005532A (en) Methods for using nitric oxide in a plasma state to treat medical conditions and diseases.
MX2013000319A (en) Treatment of cognitive disorders.
HK1202776A1 (en) Use of laquinimod for treating crohn's disease patients who failed first-line anti-tnf therapy
EA201590655A8 (en) COMBINATION OF LACHINIMODE AND PRIDOPIDINE FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS
MX2018001435A (en) TREATMENT METHODS OF LENNOX-GASTAUT SYNDROME WITH FENFLURAMINE.
PH12015500246A1 (en) Pharmaceutical combinations comprising a b-raf inhibitor, an egfr inhibitor and optionally a pi3k-alpha inhibitor
MX370953B (en) USE OF LEVOCETIRIZINE and MONTELUKAST IN THE TREATMENT OF AUTOIMMUNE DISORDERS.
WO2012093258A3 (en) Irf5- related treatment and screening
PH12017500392A1 (en) Medical treatments based on anamorelin
HK1218251A1 (en) Treatment of multiple sclerosis with laquinimod
TW201613583A (en) Laquinimod for the treatment of relapsing- remitting multiple sclerosis (RRMS) patients with a high disability status
MX344112B (en) Method and device for treating blood cholesterol disorders.
HK1200731A1 (en) Diethyl- [6- (4-hydroxycarbamoyl-phenyl-carbamoyloxy-methyl) - naphthalen-2-yl-methyl] -ammonium chloride for use in the treatment of muscular dystrophy
MX358512B (en) Methods of maintaining, treating or improving cognitive function.
HK1225969A1 (en) Treatment of crohn's disease using low doses of laquinimod
MX2016011002A (en) Treatment of hereditary angioedema with c1 inhibitor.
MENG et al. Clinical Efficacy and Safety of Proactive Therapy with 0.03% Tacrolimus for Chronic Cheilitis in Children and Adolescents.
UA59671U (en) method for medical rehabilitation of patients with chronic fatigue syndrome
Patil Flu-like symptoms and infusion related side effects: 3 case reports
RU2012110137A (en) METHOD FOR TREATING AN INSULIN RESISTANCE
UA78085U (en) method for treating patients with traumatic injury of neck department at vertebral-spinal trauma
HK1221381A1 (en) Method for treating a swallowing disorder
UA71871U (en) Method for diagnostics of effectiveness of antibiotic therapy in patients with lime-boreliosis
UA79583U (en) Method for restorative treatment of patients with essential arterial hypertension with concomitant osteochondrosis of lumbar backbone division

Legal Events

Date Code Title Description
FG Grant or registration