MX349070B - Preparacion y/o formulacion de proteinas reticuladas con polisacaridos. - Google Patents
Preparacion y/o formulacion de proteinas reticuladas con polisacaridos.Info
- Publication number
- MX349070B MX349070B MX2013005746A MX2013005746A MX349070B MX 349070 B MX349070 B MX 349070B MX 2013005746 A MX2013005746 A MX 2013005746A MX 2013005746 A MX2013005746 A MX 2013005746A MX 349070 B MX349070 B MX 349070B
- Authority
- MX
- Mexico
- Prior art keywords
- cross
- linked
- protein
- polysaccharides
- formulation
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/0059—Cosmetic or alloplastic implants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
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- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
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- A61Q19/08—Anti-ageing preparations
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
- C07K14/765—Serum albumin, e.g. HSA
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- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
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- C—CHEMISTRY; METALLURGY
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- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
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- C08B11/02—Alkyl or cycloalkyl ethers
- C08B11/04—Alkyl or cycloalkyl ethers with substituted hydrocarbon radicals
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- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
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- C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
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- C—CHEMISTRY; METALLURGY
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- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
- C08L5/10—Heparin; Derivatives thereof
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- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L89/00—Compositions of proteins; Compositions of derivatives thereof
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L89/00—Compositions of proteins; Compositions of derivatives thereof
- C08L89/04—Products derived from waste materials, e.g. horn, hoof or hair
- C08L89/06—Products derived from waste materials, e.g. horn, hoof or hair derived from leather or skin, e.g. gelatin
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61L2400/06—Flowable or injectable implant compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/34—Materials or treatment for tissue regeneration for soft tissue reconstruction
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Abstract
La presente invención se refiere a una composición que comprende al menos una matriz de proteína reticulada, en donde la al menos una matriz de proteína reticulada comprende: i) entre 1-250 mg/mL de al menos un residuo de proteína derivado de al menos una proteína portadora de amina; ii) al menos un residuo reticulado que contiene sacárido derivado de al menos una molécula reticuladora que contiene sacárido que comprende uno o más grupos carboxilo; y iii) al menos un enlace cruzado intermolecular que comprende un enlace amida entre una amina de el al menos un residuo de proteína y un grupo carboxilo de la al menos una molécula reticuladora que contiene sacárido.
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| US34494010P | 2010-11-23 | 2010-11-23 | |
| PCT/AU2011/001503 WO2012068619A1 (en) | 2010-11-23 | 2011-11-22 | Preparation and/or formulation of proteins cross-linked with polysaccharides |
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| JP2013544593A (ja) * | 2010-11-23 | 2013-12-19 | エラスタジェン ピーティーワイ リミテッド | 多糖によって架橋されているタンパク質の調製および/または調合物 |
| US20130116411A1 (en) * | 2011-09-06 | 2013-05-09 | Allergan, Inc. | Methods of making hyaluronic acid/collagen compositions |
| EP3505180B1 (en) * | 2011-09-30 | 2022-08-03 | Allergan Pharmaceuticals International Limited | In vivo synthesis of elastic fiber |
| KR101279812B1 (ko) * | 2012-05-16 | 2013-06-28 | 세원셀론텍(주) | 연골조직 수복용 조성물의 제조방법 |
| WO2014063194A1 (en) | 2012-10-23 | 2014-05-01 | The University Of Sydney | Elastic hydrogel |
| BR112015013627A2 (pt) | 2012-12-10 | 2017-07-11 | Elastagen Pty Ltd | elástico escalável tridimensional, fabricação e construção |
| JP6382311B2 (ja) * | 2013-08-13 | 2018-08-29 | エラスタジェン・プロプライエタリー・リミテッドElastagen Pty Ltd | 損傷組織の再生 |
| CN103550826B (zh) | 2013-10-31 | 2015-07-08 | 广州优得清生物科技有限公司 | 异种角膜材料的制备方法 |
| KR20150053606A (ko) * | 2013-11-08 | 2015-05-18 | 세원셀론텍(주) | 콜라겐과 히알루론산의 천연가교를 통한 고무성질의 물성이 강화된 생체재료물질 및 그 제조방법 |
| US20160143726A1 (en) * | 2014-11-26 | 2016-05-26 | Integra Lifesciences Corporation | Process for Preparing Tissue Regeneration Matrix |
| AU2016314775A1 (en) | 2015-09-01 | 2018-03-22 | Allergan Pharmaceuticals International Limited | Formation of bone |
| AU2017300392B2 (en) * | 2016-07-18 | 2022-06-16 | Tissuegen, Inc. | Methods and compositions for maintaining the conformation and structural integrity of biomolecules |
| JP6928085B2 (ja) * | 2016-08-01 | 2021-09-01 | ザ プロクター アンド ギャンブル カンパニーThe Procter & Gamble Company | 懸濁した粒子を含む相安定で噴霧可能なフレッシュニング組成物 |
| DE102016216182A1 (de) * | 2016-08-29 | 2018-03-01 | Tetec Tissue Engineering Technologies Ag | Kombination, insbesondere zum Behandeln eines Knorpeldefekts |
| JP2019218265A (ja) * | 2016-09-14 | 2019-12-26 | 生化学工業株式会社 | ペプチドの血中滞留性を増強させる方法 |
| CN107185028A (zh) * | 2017-05-05 | 2017-09-22 | 惠州华阳医疗器械有限公司 | 一种止血防粘连材料及其制备方法与应用 |
| CN109900814B (zh) * | 2017-12-08 | 2021-06-08 | 中国科学院大连化学物理研究所 | 基于糖苷键质谱可碎裂型化学交联剂的分析方法及应用 |
| LU101045B1 (en) | 2018-12-11 | 2020-06-11 | Qventis GmbH | Method for the manufacture and use of a bionic hydrogel composition for medical applications |
| EP3797800A1 (en) * | 2019-05-02 | 2021-03-31 | Institut National De La Sante Et De La Recherche Medicale - Inserm | Hyaluronic acid hydrogels with prolonged antimicrobial activity |
| EP3962517A1 (en) * | 2019-05-03 | 2022-03-09 | Allergan Pharmaceuticals International Limited | Scar prevention and/or treatment |
| WO2021229544A1 (en) | 2020-05-14 | 2021-11-18 | Allergan Pharmaceuticals International Limited | Compositions comprising tropoelastin crosslinked to hyaluronic acid and methods of use thereof |
| AU2022214780A1 (en) * | 2021-01-26 | 2023-09-07 | Immunis, Inc. | Molecular superstructure and methods of use thereof |
| WO2023092208A1 (pt) * | 2021-11-25 | 2023-06-01 | Universidade Estadual De Campinas | Processo de obtenção de solução polimérica injetável fotoreticulável, solução polimérica injetável fotoreticulável e seus usos |
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| FR2733426B1 (fr) * | 1995-04-25 | 1997-07-18 | Debacker Yves | Dispositif medical pour le comblement des deformations du volume de la peau telles que rides et cicatrices par injection de 2 formes physico-chimiques differentes d'un polymere biologique |
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| CA2307868A1 (en) * | 1998-02-17 | 1999-08-19 | Takeshi Sakai | Sulfated saccharides |
| AU4711599A (en) | 1998-06-23 | 2000-01-10 | Surgical Sealants, Incorporated | Carbodiimide cross-linked albumin for bioadhesives, surgical sealants and implantable devices |
| US6682760B2 (en) * | 2000-04-18 | 2004-01-27 | Colbar R&D Ltd. | Cross-linked collagen matrices and methods for their preparation |
| TW574302B (en) * | 2001-08-10 | 2004-02-01 | Ind Tech Res Inst | A method for producing cross-linked hyaluronic acid-protein bio-composites |
| DE10209821A1 (de) * | 2002-03-06 | 2003-09-25 | Biotechnologie Ges Mittelhesse | Kopplung von Proteinen an ein modifiziertes Polysaccharid |
| WO2005056608A1 (en) * | 2003-12-04 | 2005-06-23 | University Of Utah Research Foundation | Modified macromolecules and methods of making and using thereof |
| CN1294994C (zh) * | 2004-07-05 | 2007-01-17 | 暨南大学 | 可注射型胶原基软组织填充材料及其制备方法 |
| CA2620663A1 (en) * | 2005-09-02 | 2007-03-08 | Colbar Lifescience Ltd. | Cross-linked polysaccharide and protein matrices and methods for their preparation |
| WO2008015319A1 (fr) * | 2006-08-02 | 2008-02-07 | Khorionyx | Preparation implantable, utilisable notamment pour le complement tissulaire et la cicatrisation |
| ITMI20061726A1 (it) * | 2006-09-11 | 2008-03-12 | Fidia Farmaceutici | Derivati crosslinkati a base di acido ialuronico reticolato via click chemistry |
| EP2117620A4 (en) * | 2006-09-29 | 2010-12-01 | Martin Kean Chong Ng | PROTOELASTINE BIOMATERIALS FROM TROOELASTINE |
| EP2097115B1 (en) * | 2006-11-13 | 2017-01-25 | Elastagen Pty Ltd | Use of tropoelastin for repair or restoration of tissue |
| WO2008067655A1 (en) * | 2006-12-05 | 2008-06-12 | Q6 Biomaterials Inc. | Biocompatible hydrogel-based scaffolds |
| CN101200504B (zh) * | 2006-12-11 | 2010-05-12 | 上海百瑞吉生物医药有限公司 | 高分子巯基化改性衍生物及其交联材料 |
| US20090068250A1 (en) | 2007-09-07 | 2009-03-12 | Philippe Gravagna | Bioresorbable and biocompatible compounds for surgical use |
| US8697044B2 (en) * | 2007-10-09 | 2014-04-15 | Allergan, Inc. | Crossed-linked hyaluronic acid and collagen and uses thereof |
| CN101244290A (zh) * | 2007-11-30 | 2008-08-20 | 顾其胜 | 一种用于组织填充的交联透明质酸微粒凝胶的制备方法 |
| WO2009073668A1 (en) | 2007-12-03 | 2009-06-11 | Tenaxis Medical, Inc. | Biocompatible phase invertible proteinaceous compositions |
| WO2010053918A1 (en) * | 2008-11-05 | 2010-05-14 | Hancock Jaffe Laboratories, Inc. | Composite containing collagen and elastin as a dermal expander and tissue filler |
| JP2013544593A (ja) * | 2010-11-23 | 2013-12-19 | エラスタジェン ピーティーワイ リミテッド | 多糖によって架橋されているタンパク質の調製および/または調合物 |
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