MX367343B - Sintesis de poloxameros y poloxaminas etilenicamente insaturados polimerizables de radical libre. - Google Patents

Sintesis de poloxameros y poloxaminas etilenicamente insaturados polimerizables de radical libre.

Info

Publication number
MX367343B
MX367343B MX2015016562A MX2015016562A MX367343B MX 367343 B MX367343 B MX 367343B MX 2015016562 A MX2015016562 A MX 2015016562A MX 2015016562 A MX2015016562 A MX 2015016562A MX 367343 B MX367343 B MX 367343B
Authority
MX
Mexico
Prior art keywords
poloxamines
free radical
poloxamers
polmerizable
synthesis
Prior art date
Application number
MX2015016562A
Other languages
English (en)
Other versions
MX2015016562A (es
Inventor
Kumar Awasthi Alok
F Kunzler Jay
Satyanarayana Ganugapati
Rai Nooji Satheesha
Original Assignee
Bausch & Lomb
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bausch & Lomb filed Critical Bausch & Lomb
Publication of MX2015016562A publication Critical patent/MX2015016562A/es
Publication of MX367343B publication Critical patent/MX367343B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F290/00—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups
    • C08F290/02—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups on to polymers modified by introduction of unsaturated end groups
    • C08F290/06—Polymers provided for in subclass C08G
    • C08F290/062—Polyethers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/329—Polymers modified by chemical after-treatment with organic compounds
    • C08G65/331—Polymers modified by chemical after-treatment with organic compounds containing oxygen
    • C08G65/332—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing carboxyl groups, or halides, or esters thereof
    • C08G65/3322—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing carboxyl groups, or halides, or esters thereof acyclic
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/329—Polymers modified by chemical after-treatment with organic compounds
    • C08G65/337—Polymers modified by chemical after-treatment with organic compounds containing other elements
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/34—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from hydroxy compounds or their metallic derivatives
    • C08G65/48—Polymers modified by chemical after-treatment

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Polyethers (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

La presente invención se refiere a un nuevo método sintético para formar poloxámeros y poloxaminas funcionalizadas terminales finales polimerizables de radical libre en lotes a escala comercial los cuales usan un sistema binario de inhibidores para eliminar la formación de impurezas de alto peso molecular. También se ha descubierto de manera sorprendente que las impurezas inorgánicas formadas durante el proceso sintético a escala comercial son removidas por el uso de materiales de resina.
MX2015016562A 2013-06-18 2014-06-18 Sintesis de poloxameros y poloxaminas etilenicamente insaturados polimerizables de radical libre. MX367343B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361836471P 2013-06-18 2013-06-18
PCT/US2014/042951 WO2014205084A1 (en) 2013-06-18 2014-06-18 Synthesis of free radical polmerizable ethylenically unsaturated poloxamers and poloxamines

Publications (2)

Publication Number Publication Date
MX2015016562A MX2015016562A (es) 2016-03-31
MX367343B true MX367343B (es) 2019-08-15

Family

ID=51168448

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015016562A MX367343B (es) 2013-06-18 2014-06-18 Sintesis de poloxameros y poloxaminas etilenicamente insaturados polimerizables de radical libre.

Country Status (12)

Country Link
US (1) US9309357B2 (es)
EP (1) EP3010946B1 (es)
JP (1) JP6159025B2 (es)
KR (1) KR101767852B1 (es)
CN (1) CN105308080B (es)
AU (1) AU2014281549B2 (es)
BR (1) BR112015031653A2 (es)
CA (1) CA2914135C (es)
ES (1) ES2659759T3 (es)
MX (1) MX367343B (es)
PL (1) PL3010946T3 (es)
WO (1) WO2014205084A1 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20190292362A1 (en) * 2016-06-29 2019-09-26 Holland Novochem Technical Coatings B.V. Catalytically Active Radical Scavengers Based on Benzylic and Allylic Functionalities
US11253625B2 (en) 2018-06-27 2022-02-22 Bausch & Lomb Incorporated Ophthalmic device packaging solutions comprising a poloxamine/erythritol mixture
CN111285845B (zh) * 2020-02-11 2021-01-01 深圳厚存纳米药业有限公司 末端官能团化的泊洛沙胺衍生物
CN116018532A (zh) 2020-08-10 2023-04-25 博士伦爱尔兰有限公司 包装溶液
CN116940662A (zh) 2021-03-10 2023-10-24 博士伦爱尔兰有限公司 不含防腐剂的隐形眼镜处理溶液
US12012238B2 (en) 2021-05-26 2024-06-18 Bausch + Lomb Ireland Limited Packaging solutions
CN115616096A (zh) * 2021-07-16 2023-01-17 张家港市国泰华荣化工新材料有限公司 有机硅产品中bht和mehq的测定方法
US20230159202A1 (en) 2021-11-23 2023-05-25 Bausch + Lomb Ireland Limited Method for making a preservative-free packaged ophthalmic device product
US12510690B2 (en) 2022-02-24 2025-12-30 Bausch + Lomb Ireland Limited Ophthalmic devices
CN114948795B (zh) * 2022-07-08 2023-09-08 上海信悉智能技术有限公司 一种温敏感凝胶面膜液及其制备方法
US20240166971A1 (en) 2022-10-26 2024-05-23 Bausch + Lomb Ireland Limited Contact lens treating solution
US20240218291A1 (en) 2022-12-22 2024-07-04 Bausch + Lomb Ireland Limited Contact lens treating solution
US20240317988A1 (en) 2023-03-22 2024-09-26 Bausch + Lomb Ireland Limited Monofunctional silicone monomers and silicone hydrogels formed therefrom
US20250040673A1 (en) 2023-07-28 2025-02-06 Bausch + Lomb Ireland Limited Packaging solutions

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000007603A2 (en) * 1998-08-04 2000-02-17 Madash Llp End modified thermal responsive hydrogels
US6517933B1 (en) 2000-01-18 2003-02-11 Nano-Tex, Llc Hybrid polymer materials
CA2440844A1 (en) 2001-03-20 2002-09-26 Universitat Zurich Two-phase processing of thermosensitive polymers for use as biomaterials
JP2002296774A (ja) * 2001-03-30 2002-10-09 Fuji Photo Film Co Ltd 平版印刷版用原版
JP2005532432A (ja) * 2002-06-11 2005-10-27 ビーエーエスエフ アクチェンゲゼルシャフト ポリアルコキシル化されたトリメチロールプロパンの（メタ）アクリルエステル
US8197841B2 (en) * 2004-12-22 2012-06-12 Bausch & Lomb Incorporated Polymerizable surfactants and their use as device forming comonomers
DE102006049803A1 (de) * 2006-10-23 2008-04-30 Clariant International Limited Hydroxyfunktionelle, copolymerisierbare Polyalkylenglykol-Makromonomere, deren Herstellung und Verwendung
WO2009073374A2 (en) * 2007-12-03 2009-06-11 Bausch & Lomb Incorporated Method for inhibiting attachment of microorganisms to biomedical devices
US8293838B2 (en) * 2008-06-20 2012-10-23 Adhezion Biomedical, Llc Stable and sterile tissue adhesive composition with a controlled high viscosity
JP2013204001A (ja) * 2012-03-29 2013-10-07 Mitsubishi Chemicals Corp 活性エネルギー線硬化性樹脂組成物およびそれを用いた積層体

Also Published As

Publication number Publication date
KR101767852B1 (ko) 2017-08-11
ES2659759T3 (es) 2018-03-19
BR112015031653A2 (pt) 2017-07-25
EP3010946A1 (en) 2016-04-27
JP2016524014A (ja) 2016-08-12
KR20160019536A (ko) 2016-02-19
JP6159025B2 (ja) 2017-07-05
MX2015016562A (es) 2016-03-31
AU2014281549A1 (en) 2016-01-07
CN105308080A (zh) 2016-02-03
WO2014205084A1 (en) 2014-12-24
US9309357B2 (en) 2016-04-12
CA2914135C (en) 2017-11-14
EP3010946B1 (en) 2017-12-20
CN105308080B (zh) 2017-06-09
CA2914135A1 (en) 2014-12-24
AU2014281549B2 (en) 2017-02-02
US20140371481A1 (en) 2014-12-18
PL3010946T3 (pl) 2018-06-29

Similar Documents

Publication Publication Date Title
MX367343B (es) Sintesis de poloxameros y poloxaminas etilenicamente insaturados polimerizables de radical libre.
MY172889A (en) System and method for gas recovery and reuse
MY191132A (en) Generation of peroxyformic acid through polyhydric alcohol formate
MX2017007538A (es) Sintesis de ácido nucleíco de volúmen pequeño, alta eficiencia.
ZA201605819B (en) Method for producing a high-strength flat steel product
PT3116636T (pt) Processo e aparelho para produzir partículas de pó por atomização de um material de alimentação com a forma de um elemento alongado
MY178852A (en) Process for separating a synthetic turf product
PL3201275T3 (pl) Sposób polepszania rozkładu wielkości cząstek materiału zawierającego węglan wapnia
EP3183241A4 (en) Catalyst and process for producing 2,5-furandicarboxylic acid from hydromethylfurfural in water
PH12016501777A1 (en) Novel lactobacillus paracasei strain
MY190659A (en) Method for producing biohydrocarbons
MY174764A (en) Reduced moisture pickup in polyol-containing mineral filler products
TR201819862T4 (tr) Gadobutrol hazirlamaya yöneli̇k bi̇r yöntem
SA517381158B1 (ar) تفاعل إضافة مجموعة الكربوكسيل بتدفق مستمر
SA517390157B1 (ar) مركبات هيدروكينون معوَّقة فراغيًا كمضادات اتساخ لمونومرات غير مشبعة
MX2020008008A (es) Proceso para desvulcanizar bacterianamente particulas de caucho vulcanizadas con azufre.
PL4067461T3 (pl) Wysokowydajny proces obniżania temperatury krzepnięcia
SG11201610110UA (en) An improved process for producing pelletized polymer compositions
PH12017500440A1 (en) Dry process for preparing a surface-modified alkaline earth metal carbonate-containing material
MX2016014296A (es) Proceso para preparar un poliol polimerico.
MX2018003319A (es) Instalacion de molienda movil.
MX2017006899A (es) Sintesis de polioles polimericos en polioles insaturados, polioles polimericos y su uso.
IL253918A0 (en) Modified amines used as scale inhibitors in wet process phosphoric acid production
MX354605B (es) Metodo para dispersar y agregar componentes de suspensiones de minerales.
JO3712B1 (ar) طريقة لتحضير 1-(4-ميثان سلفونيل-2-تراي فلورو ميثيل-بنزيل)-2ميثيل-1h-بيرولو[2، 3-b]بيريدين-3-يل-حمض أسيتيك

Legal Events

Date Code Title Description
FG Grant or registration