MX376105B - Método para producir l-aminoacidos utilizando una bacteria alcalifílica. - Google Patents

Método para producir l-aminoacidos utilizando una bacteria alcalifílica.

Info

Publication number
MX376105B
MX376105B MX2016013950A MX2016013950A MX376105B MX 376105 B MX376105 B MX 376105B MX 2016013950 A MX2016013950 A MX 2016013950A MX 2016013950 A MX2016013950 A MX 2016013950A MX 376105 B MX376105 B MX 376105B
Authority
MX
Mexico
Prior art keywords
amino acids
bacteria
alkaliphic
producing
nature
Prior art date
Application number
MX2016013950A
Other languages
English (en)
Other versions
MX2016013950A (es
Inventor
Brigitte Bathe
Christian Rückert
Ines Ochrombel
Jörn Kalinowski
Marcus Persicke
Marleen Hasselmeyer
Original Assignee
Evonik Operations Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP14166633.9A external-priority patent/EP2940143B1/de
Priority claimed from DE102014208199.8A external-priority patent/DE102014208199A1/de
Application filed by Evonik Operations Gmbh filed Critical Evonik Operations Gmbh
Publication of MX2016013950A publication Critical patent/MX2016013950A/es
Publication of MX376105B publication Critical patent/MX376105B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
    • C12N9/0016—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with NAD or NADP as acceptor (1.4.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/86—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in cyclic amides, e.g. penicillinase (3.5.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y104/00—Oxidoreductases acting on the CH-NH2 group of donors (1.4)
    • C12Y104/01—Oxidoreductases acting on the CH-NH2 group of donors (1.4) with NAD+ or NADP+ as acceptor (1.4.1)
    • C12Y104/01001—Alanine dehydrogenase (1.4.1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/02—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in cyclic amides (3.5.2)
    • C12Y305/02007—Imidazolonepropionase (3.5.2.7)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/03—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amidines (3.5.3)
    • C12Y305/03013—Formimidoylglutamate deiminase (3.5.3.13)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/01—Hydro-lyases (4.2.1)
    • C12Y402/01049—Urocanate hydratase (4.2.1.49)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y403/00—Carbon-nitrogen lyases (4.3)
    • C12Y403/01—Ammonia-lyases (4.3.1)
    • C12Y403/01003—Histidine ammonia-lyase (4.3.1.3)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

Sorprendentemente, se ha descubierto alcalifilicas del g?ero Corynebacterium son naturalmente adecuadas para producir L- amino?idos.
MX2016013950A 2014-04-30 2015-04-16 Método para producir l-aminoacidos utilizando una bacteria alcalifílica. MX376105B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14166633.9A EP2940143B1 (de) 2014-04-30 2014-04-30 Verfahren zur Produktion von L-Aminosäuren unter Verwendung eines alkaliphilen Bakteriums
DE102014208199.8A DE102014208199A1 (de) 2014-04-30 2014-04-30 Verfahren zur Produktion von L-Aminosäuren unter Verwendung eines alkaliphilen Bakteriums
PCT/EP2015/058307 WO2015165746A1 (de) 2014-04-30 2015-04-16 Verfahren zur produktion von l-aminosäuren unter verwendung eines alkaliphilen bakteriums

Publications (2)

Publication Number Publication Date
MX2016013950A MX2016013950A (es) 2016-11-09
MX376105B true MX376105B (es) 2025-03-07

Family

ID=52875699

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016013950A MX376105B (es) 2014-04-30 2015-04-16 Método para producir l-aminoacidos utilizando una bacteria alcalifílica.

Country Status (10)

Country Link
US (1) US20170051323A1 (es)
JP (1) JP2017514464A (es)
KR (1) KR102250342B1 (es)
CN (1) CN106574254A (es)
BR (1) BR112016023707A2 (es)
MX (1) MX376105B (es)
MY (1) MY179341A (es)
RU (1) RU2702416C2 (es)
SG (1) SG11201608272RA (es)
WO (1) WO2015165746A1 (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2017136561A (ru) 2015-03-18 2019-04-18 Басф Се Рекомбинантный микроорганизм для улучшенного получения химических продуктов тонкого органического синтеза
KR102771842B1 (ko) 2015-11-27 2025-02-21 에보닉 오퍼레이션스 게엠베하 L-메티오닌을 제조하는 방법
GB2545261A (en) * 2015-12-11 2017-06-14 Jaguar Land Rover Ltd Control system and method of controlling a driveline
WO2018079685A1 (en) * 2016-10-26 2018-05-03 Ajinomoto Co., Inc. Method for producing objective substance
KR20200010285A (ko) * 2017-05-19 2020-01-30 지머젠 인코포레이티드 증가된 nadph를 유도하는 생합성 경로의 게놈 공학
KR102198072B1 (ko) * 2020-03-04 2021-01-04 씨제이제일제당 주식회사 글루타민 신테타아제 변이형 폴리펩티드 및 이를 이용한 l-글루타민 생산 방법
KR102344689B1 (ko) * 2020-09-01 2021-12-29 씨제이제일제당 주식회사 L-발린 생산 미생물 및 이를 이용한 l-발린 생산 방법
JP7584632B2 (ja) * 2020-09-09 2024-11-15 シージェイ チェイルジェダン コーポレーション Ｌ－グルタミン酸生産組換え微生物及びそれを用いたｌ－グルタミン酸製造方法
CN114686410B (zh) * 2020-12-25 2023-11-21 泰兴市东圣生物科技有限公司 一种增强1-磷酸果糖激酶基因转录水平的谷氨酰胺转氨酶高产菌株及其制备与发酵方法
KR102254628B1 (ko) * 2021-01-15 2021-05-21 씨제이제일제당 주식회사 신규한 포름이미도일글루타마아제 변이체 및 이를 이용한 imp 생산 방법
KR102258159B1 (ko) * 2021-01-29 2021-05-27 씨제이제일제당 (주) 신규한 말레이트 디하이드로게나제 변이체 및 이를 이용한 l-라이신 생산 방법
JP7728880B2 (ja) 2021-04-01 2025-08-25 エボニック オペレーションズ ゲーエムベーハー Ｌ－グルホシネートおよびそのホスホエステルを産生するための酵素的方法
KR20240167719A (ko) * 2022-03-01 2024-11-27 메타볼릭 익스플로러 류신 및/또는 이소류신의 개선된 생산을 위한 미생물 및 방법
CN114507273B (zh) * 2022-03-14 2024-05-07 宁夏伊品生物科技股份有限公司 Yh66_07020蛋白及其相关生物材料在提高精氨酸产量中的应用
CN119907861A (zh) 2022-09-21 2025-04-29 赢创运营有限公司 用于生产l-草铵膦及其磷酸脂的酶促催化方法
KR20240138673A (ko) * 2023-03-10 2024-09-20 씨제이제일제당 (주) L-알라닌 생산 미생물 및 이를 이용한 l-알라닌 생산 방법
EP4735580A1 (en) * 2023-06-28 2026-05-06 Westlake University Regulation of cellular energy metabolism by lipoate protein ligase and its applications
KR20250169493A (ko) * 2024-05-24 2025-12-03 씨제이제일제당 (주) 리포에이트 단백질 리가아제의 활성이 강화된 미생물 및 이의 용도

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3151075B2 (ja) * 1992-12-22 2001-04-03 協和醗酵工業株式会社 アラニンの製造法
JP4623825B2 (ja) * 1999-12-16 2011-02-02 協和発酵バイオ株式会社 新規ポリヌクレオチド
DE102004008445A1 (de) * 2004-02-19 2005-09-08 Degussa Ag Verfahren zur Herstellung von L-Aminosäuren aus D-Aminosäuren
US20090209012A1 (en) * 2005-06-09 2009-08-20 Daicel Chemical Industries, Ltd. Method for producing l-amino acids
WO2008119009A2 (en) * 2007-03-27 2008-10-02 University Of Florida Research Foundation, Inc. Materials and methods for efficient alanine production

Also Published As

Publication number Publication date
RU2016144069A3 (es) 2018-12-05
KR20160145827A (ko) 2016-12-20
MY179341A (en) 2020-11-04
BR112016023707A2 (pt) 2017-10-17
JP2017514464A (ja) 2017-06-08
WO2015165746A1 (de) 2015-11-05
US20170051323A1 (en) 2017-02-23
KR102250342B1 (ko) 2021-05-10
SG11201608272RA (en) 2016-11-29
RU2702416C2 (ru) 2019-10-08
RU2016144069A (ru) 2018-05-15
MX2016013950A (es) 2016-11-09
CN106574254A (zh) 2017-04-19

Similar Documents

Publication Publication Date Title
MY179341A (en) Method for producing l-amino acids using an alkaliphilic bacteria
CY1123065T1 (el) Ανασυνδυασμενα προβιοτικα βακτηριδια
CO2017002170A2 (es) Terapia de combinación para tratar un paramixovirus
CO2017004386A2 (es) Fluidos de estimulación de lgn de grado y
MX2017007148A (es) Bacterias modificadas para tratar enfermedades asociadas con hiperamonemia.
CA158059S (en) Refrigerating apparatus
EP3960735C0 (en) QUINAZOLINE DERIVATIVES USED TO TREAT HIV
DK3153573T3 (da) Mikroorganisme af slægten Corynebacterium til fremstilling af L-arginin og fremgangsmåde til fremstilling af L-arginin under anvendelse af samme
MX2016009590A (es) Composiciones de apilimod y métodos para usar las mismas.
MX2017005975A (es) Anticuerpos anti factor de crecimiento derivado de plaquetas b (pdgf-b) y metodos de uso.
MX2017006019A (es) Apilimod para uso en el tratamiento de melanoma.
MY175423A (en) Microorganism having improved ability to produce l-lysine and method for producing l-lysine using same
BR112017008097A2 (pt) método para tratar condições oculares
DK3144383T3 (da) Mikroorganisme af Corynebacterium-slægten til fremstilling af L-lysin og fremgangsmåde til fremstilling af L-lysin under anvendelse af denne
CA158058S (en) Refrigerating apparatus
HUE048849T2 (hu) Corynebacterium nemzetségbe tartozó mikroorganizmus L-aminosav elõállítására és eljárás L-aminosav elõállítására annak alkalmazásával
UA114997C2 (uk) Рекомбінантний мікроорганізм з роду escherichia, що виробляє l-амінокислоту, та спосіб одержання l-амінокислоти
PL3130663T3 (pl) Mikroorganizm posiadający zdolność produkcji L-lizyny i sposób wytwarzania L-lizyny przy jego zastosowaniu
PL2940143T3 (pl) Sposób wytwarzania L-aminokwasów z użyciem bakterii bazofilowych
EA201991474A1 (ru) Способы получения фитоина
PH12016501780A1 (en) Rna production in higher plants
DK3196300T3 (da) Mikroorganisme med forbedret L-lysin-produktivitet og fremgangsmåde til fremstilling af L-lysin under anvendelse af samme
CL2014003349A1 (es) Proceso y método para la mejora sustentable de la producción de mariscos en aguas oceánicas.
UA96801U (uk) Спосіб обробки водно-спиртової суміші
TH1501004303A (th) จุลินทรีย์และวิธีสำหรับการผลิตกรดอะมิโนโดยการหมัก

Legal Events

Date Code Title Description
HC Change of company name or juridical status

Owner name: RALLYBIO IPA, LLC

FG Grant or registration