MX376307B - Derivados de oxazetidina, proceso para su preparacion y uso de los mismos en medicina humana y en cosmetica. - Google Patents

Derivados de oxazetidina, proceso para su preparacion y uso de los mismos en medicina humana y en cosmetica.

Info

Publication number
MX376307B
MX376307B MX2014000170A MX2014000170A MX376307B MX 376307 B MX376307 B MX 376307B MX 2014000170 A MX2014000170 A MX 2014000170A MX 2014000170 A MX2014000170 A MX 2014000170A MX 376307 B MX376307 B MX 376307B
Authority
MX
Mexico
Prior art keywords
compounds
oxazetidine
cosmetics
derivatives
preparation
Prior art date
Application number
MX2014000170A
Other languages
English (en)
Other versions
MX2014000170A (es
Inventor
Claire Bouix-Peter
Original Assignee
Galderma Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galderma Res & Dev filed Critical Galderma Res & Dev
Publication of MX2014000170A publication Critical patent/MX2014000170A/es
Publication of MX376307B publication Critical patent/MX376307B/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A—HUMAN NECESSITIES
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    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
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    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
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  • Health & Medical Sciences (AREA)
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  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
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  • Pharmacology & Pharmacy (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
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  • Dermatology (AREA)
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  • Birds (AREA)
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Abstract

La presente invención se relaciona con el campo farmacéutico y en particular al tratamiento de patologías hipopigmentarias y dermatosis fotosensible. Más específicamente, la invención se relaciona con compuestos que son agonistas del receptor MC1R y que exhibe toxicidad reducida en relación con otros compuestos de la misma clase. Estos compuestos tienen la fórmula general (I) a continuación: en la cual R1 representa un ciclopropilmetil o un grupo 4-hidroxibutil; R2 representa un átomo de hidrógeno o un grupo metilo; y también las sales y enantiómeros de los compuestos correspondientes de la fórmula general (I).
MX2014000170A 2011-06-30 2012-06-28 Derivados de oxazetidina, proceso para su preparacion y uso de los mismos en medicina humana y en cosmetica. MX376307B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161503068P 2011-06-30 2011-06-30
FR1159911A FR2981933B1 (fr) 2011-11-02 2011-11-02 Derives d'oxoazetidine, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique
PCT/EP2012/062622 WO2013001030A1 (en) 2011-06-30 2012-06-28 Oxazetidine derivatives, process for preparing them and use thereof in human medicine and in cosmetics

Publications (2)

Publication Number Publication Date
MX2014000170A MX2014000170A (es) 2014-02-19
MX376307B true MX376307B (es) 2025-03-07

Family

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Application Number Title Priority Date Filing Date
MX2014000170A MX376307B (es) 2011-06-30 2012-06-28 Derivados de oxazetidina, proceso para su preparacion y uso de los mismos en medicina humana y en cosmetica.

Country Status (14)

Country Link
US (2) US9353083B2 (es)
EP (1) EP2726478B1 (es)
JP (1) JP5898310B2 (es)
KR (1) KR101946085B1 (es)
AR (1) AR086803A1 (es)
AU (1) AU2012277838B2 (es)
BR (1) BR112013033861B1 (es)
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BR112018075734A2 (pt) 2016-06-13 2019-04-02 Gilead Sciences, Inc. composto, composição farmacêutica, método para tratar um paciente com uma doença ou condição mediada pelo menos em parte por fxr, e, uso de um composto.
ES2985745T3 (es) * 2017-02-01 2024-11-07 Vallaurix Mc S A R L Análogos de alfa-MSH utilizados en el tratamiento de Xeroderma Pigmentosum
CN110461328A (zh) 2017-03-28 2019-11-15 吉利德科学公司 治疗肝疾病的治疗组合
US11524005B2 (en) 2019-02-19 2022-12-13 Gilead Sciences, Inc. Solid forms of FXR agonists
BR112022025115A2 (pt) * 2020-06-10 2023-02-07 Mitsubishi Tanabe Pharma Corp Agente profilático ou terapêutico para fotodermatose

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EP2726478B1 (en) 2017-01-11
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FR2981933A1 (fr) 2013-05-03
FR2981933B1 (fr) 2013-11-15
JP5898310B2 (ja) 2016-04-06
IN2014CN00711A (es) 2015-04-03
BR112013033861B1 (pt) 2021-11-09
AU2012277838B2 (en) 2017-04-13
AR086803A1 (es) 2014-01-22
US9981952B2 (en) 2018-05-29
RU2624011C2 (ru) 2017-06-30
RU2014102966A (ru) 2015-08-10
MX2014000170A (es) 2014-02-19
EP2726478A1 (en) 2014-05-07
CA2840606A1 (en) 2013-01-03
BR112013033861A2 (pt) 2017-12-19
WO2013001030A1 (en) 2013-01-03
KR101946085B1 (ko) 2019-02-08
JP2014518238A (ja) 2014-07-28
US20140228342A1 (en) 2014-08-14
US20160237065A1 (en) 2016-08-18
US9353083B2 (en) 2016-05-31
CN103827106A (zh) 2014-05-28
ES2620476T3 (es) 2017-06-28

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