MX9802143A - Agentes antitumorales de tioxantenona liofilizados. - Google Patents

Agentes antitumorales de tioxantenona liofilizados.

Info

Publication number
MX9802143A
MX9802143A MX9802143A MX9802143A MX9802143A MX 9802143 A MX9802143 A MX 9802143A MX 9802143 A MX9802143 A MX 9802143A MX 9802143 A MX9802143 A MX 9802143A MX 9802143 A MX9802143 A MX 9802143A
Authority
MX
Mexico
Prior art keywords
thioxanthenone
antimumor
lyophilized
agents
mannitol
Prior art date
Application number
MX9802143A
Other languages
English (en)
Other versions
MXPA98002143A (es
Inventor
Stephen Brown
Gurdial Singh Sandu
Original Assignee
Sanofi Winthrop Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Winthrop Inc filed Critical Sanofi Winthrop Inc
Publication of MX9802143A publication Critical patent/MX9802143A/es
Publication of MXPA98002143A publication Critical patent/MXPA98002143A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/67—Phosphorus compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/382—Heterocyclic compounds having sulfur as a ring hetero atom having six-membered rings, e.g. thioxanthenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)

Abstract

Se describen formulaciones liofilizadas reconstituidas para el tratamiento de tumores de mamíferos que comprenden un agente antitumoral de tioxantenona en combinacion con manitol o sacarosa como un estabilizante en un amortiguador de lactato.
MXPA/A/1998/002143A 1995-09-18 1998-03-17 Agentes antitumorales de tioxantenona liofilizados MXPA98002143A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/529,934 US5665760A (en) 1995-09-18 1995-09-18 Lyophilized thioxanthenone antitumor agents
US08529934 1995-09-18
PCT/IB1996/000984 WO1997010809A1 (en) 1995-09-18 1996-09-12 Lyophilized thioxanthenone antimumor agents

Publications (2)

Publication Number Publication Date
MX9802143A true MX9802143A (es) 1998-05-31
MXPA98002143A MXPA98002143A (es) 1998-10-23

Family

ID=

Also Published As

Publication number Publication date
KR100475385B1 (ko) 2006-03-23
CN1201387A (zh) 1998-12-09
RU2157189C2 (ru) 2000-10-10
ATE235888T1 (de) 2003-04-15
WO1997010809A1 (en) 1997-03-27
PL325603A1 (en) 1998-08-03
EP0917458B1 (en) 2003-04-02
KR19990045741A (ko) 1999-06-25
DK0917458T3 (da) 2003-07-28
CZ79998A3 (cs) 1998-08-12
DE69627209T2 (de) 2004-02-19
PL185164B1 (pl) 2003-03-31
DE69627209D1 (en) 2003-05-08
PT917458E (pt) 2003-08-29
AU716782B2 (en) 2000-03-09
HK1016891A1 (zh) 1999-11-12
CA2232444A1 (en) 1997-03-27
NZ316609A (en) 1999-05-28
US5665760A (en) 1997-09-09
CZ293433B6 (cs) 2004-04-14
AU6888096A (en) 1997-04-09
EP0917458A1 (en) 1999-05-26
NO981205D0 (no) 1998-03-17
HUP9900246A2 (hu) 2001-04-28
HUP9900246A3 (en) 2002-12-28
NO320367B1 (no) 2005-11-28
NO981205L (no) 1998-05-15
ES2196171T3 (es) 2003-12-16
JP2001503374A (ja) 2001-03-13
CN1178651C (zh) 2004-12-08

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Legal Events

Date Code Title Description
FG Grant or registration
MM Annulment or lapse due to non-payment of fees