MY102597A - Cyclic peptide derivatives - Google Patents

Cyclic peptide derivatives

Info

Publication number
MY102597A
MY102597A MYPI87001895A MYPI19871895A MY102597A MY 102597 A MY102597 A MY 102597A MY PI87001895 A MYPI87001895 A MY PI87001895A MY PI19871895 A MYPI19871895 A MY PI19871895A MY 102597 A MY102597 A MY 102597A
Authority
MY
Malaysia
Prior art keywords
factors
alkanoyl
group
cyclic peptide
amino
Prior art date
Application number
MYPI87001895A
Inventor
Debono Manuel
John Abbott Bernard
Shuichi Fukuda David
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/380,498 external-priority patent/US4399067A/en
Priority claimed from US06/380,499 external-priority patent/US4396543A/en
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of MY102597A publication Critical patent/MY102597A/en

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

A- 21978C CYCLIC PEPTIDES OF THE FORMULA HEREIN R IS SELECTED FROM THE GROUP CONSISTING OF HYDROGEN, AN AMINO- PROTECTING GROUP, 8 - METHYLDECANOYL, 10 - METHYLUNDECANOYL, 10 - METHYLDODCANOYL, THE SPECIFIC C10 - ALKANOYL GROUP OF A - 21978C FACTOR C0 AND THE SPECIFIC C12 - ALKANOYL GROUPS OF A- 21978C FACTORS C4 AND C5 ; R1 AND R2 ARE INDEPENDENTLY, HYDROGEN OR AN AMINO - PROTECTING GROUP AND SALTS THEREOF ARE PREPARED BY ENZYMATIC DEACYLATION OF AN ANTIBIOTIC SELECTED FROM A - 21978C COMPLEX, A - 21978C FACTORS C0, C1, C2, C3, C4 AND C5 AND BLOCKED A- 21978C COMPLEX AND FACTORS C0, C1, C2, C3, C4 AND C5 USING AN ENZYME PRODUCED BY THE ACTINOPLANACEAC, PREFERABLY BY ACTINOPLANES UTAHENSIS. THESE A - 21978A CYCLIC PEPTIDES OR A PHARMACEUTICALLY - ACCEPTABLE SALT THEREOF ARE USEFUL INTERMEDIATES FOR PREPARING NEW ALKANOYL, ALKENOYL, BENZOYL, ACYLAMINO, N - ALKANOYLAMINOACYL, AND ALKYL CYCLIC PEPTIDE ANTIBIOTICS.
MYPI87001895A 1982-05-21 1987-09-23 Cyclic peptide derivatives MY102597A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US38049782A 1982-05-21 1982-05-21
US06/380,498 US4399067A (en) 1982-05-21 1982-05-21 Derivatives of A-21978C cyclic peptides
US06/380,499 US4396543A (en) 1982-05-21 1982-05-21 Derivatives of A-21978C cyclic peptides

Publications (1)

Publication Number Publication Date
MY102597A true MY102597A (en) 1992-08-17

Family

ID=79730906

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI87001895A MY102597A (en) 1982-05-21 1987-09-23 Cyclic peptide derivatives

Country Status (1)

Country Link
MY (1) MY102597A (en)

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