MY104178A - Substituted 4-azatricyclo [22.3.1.04,9] octacos-18- ene derivatives, their preparation and pharmaceutical compositions containing them. - Google Patents
Substituted 4-azatricyclo [22.3.1.04,9] octacos-18- ene derivatives, their preparation and pharmaceutical compositions containing them.Info
- Publication number
- MY104178A MY104178A MYPI89001163A MYPI19891163A MY104178A MY 104178 A MY104178 A MY 104178A MY PI89001163 A MYPI89001163 A MY PI89001163A MY PI19891163 A MYPI19891163 A MY PI19891163A MY 104178 A MY104178 A MY 104178A
- Authority
- MY
- Malaysia
- Prior art keywords
- octacos
- azatricyclo
- substituted
- preparation
- pharmaceutical compositions
- Prior art date
Links
- WBYBDYREXOJFOB-UHFFFAOYSA-N 4-azatricyclo[22.3.1.04,9]octacos-18-ene Chemical class C1CCCC=CCCCCCCCCC2CCCCN2CCC2CCCC1C2 WBYBDYREXOJFOB-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- -1 ALLYL Chemical group 0.000 abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 2
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000018044 dehydration Effects 0.000 abstract 1
- 238000006297 dehydration reaction Methods 0.000 abstract 1
- 238000000855 fermentation Methods 0.000 abstract 1
- 230000004151 fermentation Effects 0.000 abstract 1
- 238000005984 hydrogenation reaction Methods 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical group [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 abstract 1
- 229960003444 immunosuppressant agent Drugs 0.000 abstract 1
- 230000001861 immunosuppressant effect Effects 0.000 abstract 1
- 239000003018 immunosuppressive agent Substances 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
THE COMPOUNDS OF FORMULA I WHEREIN EITHER R1 IS HYDROXY, R2 IS ALLYL OR N-PROPYL AND THERE IS A SINGLE BOND BETWEEN THE CARBON ATOMS NUMBERED 14 AND 15 OR R1 IS MISSING, R2 IS ALLYL AND THERE IS A DOUBLE BOND BETWEEN THE CARBON ATOMS NUMBER 14 AND 15, HAVE INTERESTING IMMUNOSUPPRESSANT AND ANTI-INFLAMMATORY PROPERTIES. THEY ARE OBTAINED BY FERMENTATION OR SYNTHESIS, E.G. BY HYDROGENATION OR DEHYDRATION.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB888820348A GB8820348D0 (en) | 1988-08-26 | 1988-08-26 | Macrolides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY104178A true MY104178A (en) | 1994-02-28 |
Family
ID=10642804
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI89001163A MY104178A (en) | 1988-08-26 | 1989-08-24 | Substituted 4-azatricyclo [22.3.1.04,9] octacos-18- ene derivatives, their preparation and pharmaceutical compositions containing them. |
Country Status (4)
| Country | Link |
|---|---|
| GB (1) | GB8820348D0 (en) |
| MY (1) | MY104178A (en) |
| NZ (1) | NZ230418A (en) |
| ZA (1) | ZA896524B (en) |
-
1988
- 1988-08-26 GB GB888820348A patent/GB8820348D0/en active Pending
-
1989
- 1989-08-24 NZ NZ23041889A patent/NZ230418A/en unknown
- 1989-08-24 MY MYPI89001163A patent/MY104178A/en unknown
- 1989-08-25 ZA ZA896524A patent/ZA896524B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GB8820348D0 (en) | 1988-09-28 |
| ZA896524B (en) | 1991-04-24 |
| NZ230418A (en) | 1991-10-25 |
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