MY105097A - Nanbv diagnostics and vaccines - Google Patents
Nanbv diagnostics and vaccinesInfo
- Publication number
- MY105097A MY105097A MYPI88001618A MYPI19881618A MY105097A MY 105097 A MY105097 A MY 105097A MY PI88001618 A MYPI88001618 A MY PI88001618A MY PI19881618 A MYPI19881618 A MY PI19881618A MY 105097 A MY105097 A MY 105097A
- Authority
- MY
- Malaysia
- Prior art keywords
- sequences
- hcv
- virus
- hepatitis
- individuals
- Prior art date
Links
- 229960005486 vaccine Drugs 0.000 title 1
- 241000711549 Hepacivirus C Species 0.000 abstract 7
- 206010019786 Hepatitis non-A non-B Diseases 0.000 abstract 3
- 241000724709 Hepatitis delta virus Species 0.000 abstract 2
- 239000003153 chemical reaction reagent Substances 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 241000710831 Flavivirus Species 0.000 abstract 1
- 241000700721 Hepatitis B virus Species 0.000 abstract 1
- 208000037262 Hepatitis delta Diseases 0.000 abstract 1
- 241000709721 Hepatovirus A Species 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 239000003443 antiviral agent Substances 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 208000029570 hepatitis D virus infection Diseases 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Landscapes
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
A FAMILY OF CDNA SEQUENCES DERIVED FROM HEPATITIS C VIRUS (HCV) ARE PROVIDED. THESE SEQUENCES ENCODE ANTIGENS WHICH REACT IMMUNOLOGICALLY WITH ANTIBODIES PRESENT IN INDIVIDUALS WITH NON-A NON-B HEPATITIS (NANBH), BUT WHICH ARE ABSENT FROM INDIVIDUALS INFECTED WITH HEPATITIS A VIRUS, OR HEPATITIS B VIRUS, AND ALSO ARE ABSENT IN CONTROL INDIVIDUALS. THE HCV CDNA SEQUENCES LACK SUBSTANTIAL HOMOLOGY TO THE SEQUENCES OF HEPATITIS DELTA VIRUS (HDV) AND HBV. A COMPARISON OF THE SEQUENCES OF AMINO ACIDS ENCODED IN THE HCV CDNA WITH THE SEQUENCES OF FLAVIRUSES INDICATES THAT HVC IS A FLAVIVIRUS OR FLAVILIKE VIRUS. THE HCV CDNA SEQUENCES AND THE POLYPEPTIDES ENCODED THEREIN ARE USEFUL AS REAGENTS FOR THE DETECTION AND THERAPY OF HCV. THE REAGENTS PROVIDED IN THE INVENTION ARE ALSO USEFUL FOR THE ISOLATION OF NANBH AGENT (S), FOR THE PROPAGATION OF THESE AGENTS IN TISSUE CULTURE, AND FOR THE SCREENING OF ANTIVIRAL AGENTS FOR HCV.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12271487A | 1987-11-18 | 1987-11-18 | |
| US13988687A | 1987-12-30 | 1987-12-30 | |
| US16107288A | 1988-02-26 | 1988-02-26 | |
| US19126388A | 1988-05-06 | 1988-05-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY105097A true MY105097A (en) | 1994-08-30 |
Family
ID=79604018
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI88001618A MY105097A (en) | 1987-11-18 | 1988-12-31 | Nanbv diagnostics and vaccines |
Country Status (1)
| Country | Link |
|---|---|
| MY (1) | MY105097A (en) |
-
1988
- 1988-12-31 MY MYPI88001618A patent/MY105097A/en unknown
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