MY105595A - Stable aqueous solutions of primycin pharmaceutical and cosmetic compositions containing these solutions and process for preparing same - Google Patents
Stable aqueous solutions of primycin pharmaceutical and cosmetic compositions containing these solutions and process for preparing sameInfo
- Publication number
- MY105595A MY105595A MYPI90000425A MYPI19900425A MY105595A MY 105595 A MY105595 A MY 105595A MY PI90000425 A MYPI90000425 A MY PI90000425A MY PI19900425 A MYPI19900425 A MY PI19900425A MY 105595 A MY105595 A MY 105595A
- Authority
- MY
- Malaysia
- Prior art keywords
- primycin
- volume
- solutions
- pharmaceutical
- mass
- Prior art date
Links
- NYWSLZMTZNODJM-MCGDBQAWSA-N 2-[5-[(4e,20e)-35-butyl-19-[(2s,3s,4s,5r)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-10,12,14,16,18,22,26,30,34-nonahydroxy-3,5,21,33-tetramethyl-36-oxo-1-oxacyclohexatriaconta-4,20-dien-2-yl]-4-hydroxyhexyl]guanidine Chemical compound OC1CC(O)CC(O)CC(O)CC(O)CCCC\C(C)=C\C(C)C(C(C)C(O)CCCN=C(N)N)OC(=O)C(CCCC)C(O)C(C)CCC(O)CCCC(O)CCCC(O)\C(C)=C\C1O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O1 NYWSLZMTZNODJM-MCGDBQAWSA-N 0.000 title abstract 4
- 229950010664 primycin Drugs 0.000 title abstract 4
- NYWSLZMTZNODJM-SDUQVVOESA-N primycin Natural products CCCC[C@H]1[C@H](O)[C@H](C)CC[C@@H](O)CCC[C@@H](O)CCC[C@@H](O)C(=C[C@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@@H]2O)[C@@H](O)C[C@H](O)C[C@@H](O)C[C@H](O)C[C@H](O)CCCCC(=C[C@@H](C)[C@@H](OC1=O)[C@H](C)[C@H](O)CCCNC(=N)N)C)C NYWSLZMTZNODJM-SDUQVVOESA-N 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 3
- 239000002537 cosmetic Substances 0.000 title abstract 2
- 239000007864 aqueous solution Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000000243 solution Substances 0.000 title 1
- ODHCTXKNWHHXJC-VKHMYHEASA-N 5-oxo-L-proline Chemical compound OC(=O)[C@@H]1CCC(=O)N1 ODHCTXKNWHHXJC-VKHMYHEASA-N 0.000 abstract 2
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 abstract 2
- ODHCTXKNWHHXJC-UHFFFAOYSA-N acide pyroglutamique Natural products OC(=O)C1CCC(=O)N1 ODHCTXKNWHHXJC-UHFFFAOYSA-N 0.000 abstract 2
- SECXISVLQFMRJM-UHFFFAOYSA-N N-Methylpyrrolidone Chemical compound CN1CCCC1=O SECXISVLQFMRJM-UHFFFAOYSA-N 0.000 abstract 1
- BZARQXGRENRAGM-YQALYVIGSA-N OS(O)(=O)=O.CCCCC1C(O)C(C)CCC(O)CCCC(O)CCCC(O)\C(C)=C\C(OC2OC(CO)C(O)C2O)C(O)CC(O)CC(O)CC(O)CC(O)CCCC\C(C)=C\C(C)C(OC1=O)C(C)C(O)CCCN=C(N)N.CCCCC1C(O)C(C)CCC(O)CCCC(O)CCCC(O)\C(C)=C\C(OC2OC(CO)C(O)C2O)C(O)CC(O)CC(O)CC(O)CC(O)CCCC\C(C)=C\C(C)C(OC1=O)C(C)C(O)CCCN=C(N)N Chemical compound OS(O)(=O)=O.CCCCC1C(O)C(C)CCC(O)CCCC(O)CCCC(O)\C(C)=C\C(OC2OC(CO)C(O)C2O)C(O)CC(O)CC(O)CC(O)CC(O)CCCC\C(C)=C\C(C)C(OC1=O)C(C)C(O)CCCN=C(N)N.CCCCC1C(O)C(C)CCC(O)CCCC(O)CCCC(O)\C(C)=C\C(OC2OC(CO)C(O)C2O)C(O)CC(O)CC(O)CC(O)CC(O)CCCC\C(C)=C\C(C)C(OC1=O)C(C)C(O)CCCN=C(N)N BZARQXGRENRAGM-YQALYVIGSA-N 0.000 abstract 1
- ODHCTXKNWHHXJC-GSVOUGTGSA-N Pyroglutamic acid Natural products OC(=O)[C@H]1CCC(=O)N1 ODHCTXKNWHHXJC-GSVOUGTGSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 229940121363 anti-inflammatory agent Drugs 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 230000000249 desinfective effect Effects 0.000 abstract 1
- 239000003410 keratolytic agent Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- NOJNFULGOQGBKB-UHFFFAOYSA-M sodium;3-[3-tert-butylsulfanyl-1-[[4-(6-ethoxypyridin-3-yl)phenyl]methyl]-5-[(5-methylpyridin-2-yl)methoxy]indol-2-yl]-2,2-dimethylpropanoate Chemical compound [Na+].C1=NC(OCC)=CC=C1C(C=C1)=CC=C1CN1C2=CC=C(OCC=3N=CC(C)=CC=3)C=C2C(SC(C)(C)C)=C1CC(C)(C)C([O-])=O NOJNFULGOQGBKB-UHFFFAOYSA-M 0.000 abstract 1
- 230000001502 supplementing effect Effects 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
THE INVENTION RELATES TO NOVEL STABLE AQUEOUS PRIMYCYN SOLUTIONS CONTAINING 0.5 TO 1.75% BY MASS/VOLUME OF PRIMYCIN SULFATE OR 2.5 TO 9% BY MASS/VOLUME OF A COMPLEX OF PRIMYCIN WITH N-METHYLPIRROLIDONE AND 2 TO 15% BY MASS/VOLUME OF PYROGLUTAMIC ACID, PREFERABLY L-PYROGLUTAMIC ACID OR A SOLUBLE SALT, PREFERABLY THE SODIUM SALT THEREOF AS CALCULATED FOR THE VOLUME OF THE SOLUTION TO BE PREPARED AND 40 TO 60% BY VOLUME OF ISOPROPANOL AS CALCULATED FOR THE VOLUME OF THE SOLUTION TO BE PREPARED AS WELL AS WATER IN AN AMOUNT SUPPLEMENTING UP TO 100 %.THE INVENTION FURTHER RELATES TO PHARMACEUTICAL OR DISINFECTING COSMETIC COMPOSITIONS MAINLY FOR TOPICAL TREATMENT CONTAINING THE ABOVE PRIMYCIN SOLUTION OPTIONALLY IN ADMIXTURE WITH PHARMACEUTICALLY ACCEPTABLE AUXILIARY MATERIALS AND, IF DESIRED, WITH OTHER NON-SYNERGISTIC THERAPEUTICALLY ACTIVE INGREDIENT(S), SUITABLY DESQUAMATING AND/OR ANTIINFLAMMATORY AGENT(S). THE INVENTION FURTHER RELATES TO THE PREPARATION OF THE ABOVE PRIMYCIN SOLUTIONS AND COMPOSITIONS CONTAINING THESE SOLUTIONS.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MYPI90000425A MY105595A (en) | 1990-03-19 | 1990-03-19 | Stable aqueous solutions of primycin pharmaceutical and cosmetic compositions containing these solutions and process for preparing same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MYPI90000425A MY105595A (en) | 1990-03-19 | 1990-03-19 | Stable aqueous solutions of primycin pharmaceutical and cosmetic compositions containing these solutions and process for preparing same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY105595A true MY105595A (en) | 1994-11-30 |
Family
ID=79554180
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI90000425A MY105595A (en) | 1990-03-19 | 1990-03-19 | Stable aqueous solutions of primycin pharmaceutical and cosmetic compositions containing these solutions and process for preparing same |
Country Status (1)
| Country | Link |
|---|---|
| MY (1) | MY105595A (en) |
-
1990
- 1990-03-19 MY MYPI90000425A patent/MY105595A/en unknown
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