MY105822A - Combined use of n-imidazolyl derivatives of bicyclic compounds and cyclosporine in therapy. - Google Patents

Combined use of n-imidazolyl derivatives of bicyclic compounds and cyclosporine in therapy.

Info

Publication number: MY105822A
Authority: MY; Malaysia
Prior art keywords: hydrogen; cyclosporine; alkyl; therapy; bicyclic compounds
Prior art date: 1989-06-23

Application number

MYPI90001063A

Other languages

English (en)

Inventor

Ferti Corrado

Alessandrini Paola

Cozzi Paolo

Salvati Patricia

Original Assignee

Erba Carlo Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-06-23

Filing date

1990-06-22

Publication date

1995-01-30

1990-06-22 Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa

1995-01-30 Publication of MY105822A publication Critical patent/MY105822A/en

Links

PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 title abstract 3
108010036949 Cyclosporine Proteins 0.000 title abstract 3
229960001265 ciclosporin Drugs 0.000 title abstract 3
150000001875 compounds Chemical class 0.000 title abstract 3
229930182912 cyclosporin Natural products 0.000 title abstract 2
238000002560 therapeutic procedure Methods 0.000 title 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical group [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 4
229910052739 hydrogen Inorganic materials 0.000 abstract 4
239000001257 hydrogen Substances 0.000 abstract 4
229930105110 Cyclosporin A Natural products 0.000 abstract 1
241000124008 Mammalia Species 0.000 abstract 1
-1 N-IMIDAZOLYL Chemical class 0.000 abstract 1
206010029164 Nephrotic syndrome Diseases 0.000 abstract 1
CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical class [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical class [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 abstract 1
208000009928 nephrosis Diseases 0.000 abstract 1
231100001027 nephrosis Toxicity 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
239000001301 oxygen Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Immunology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Transplantation (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Plural Heterocyclic Compounds (AREA)

MYPI90001063A 1989-06-23 1990-06-22 Combined use of n-imidazolyl derivatives of bicyclic compounds and cyclosporine in therapy. MY105822A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB898914525A GB8914525D0 (en)	1989-06-23	1989-06-23	Combined use of n-imidazolyl derivatives of bicyclic compounds and cyclosporine in therapy

Publications (1)

Publication Number	Publication Date
MY105822A true MY105822A (en)	1995-01-30

Family

ID=10658992

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MYPI90001063A MY105822A (en)	1989-06-23	1990-06-22	Combined use of n-imidazolyl derivatives of bicyclic compounds and cyclosporine in therapy.

Country Status (13)

Country	Link
EP (1)	EP0433427A1 (ja)
JP (1)	JPH04500375A (ja)
KR (1)	KR920700669A (ja)
AU (1)	AU636898B2 (ja)
CA (1)	CA2035032A1 (ja)
GB (1)	GB8914525D0 (ja)
HU (1)	HUT55989A (ja)
IE (1)	IE902266A1 (ja)
IL (1)	IL94765A0 (ja)
MY (1)	MY105822A (ja)
PT (1)	PT94464A (ja)
WO (1)	WO1991000102A1 (ja)
ZA (1)	ZA904882B (ja)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL91542A0 (en) *	1988-10-06	1990-04-29	Erba Carlo Spa	N-imidazolyl-and n-imidazolyl-methyl derivatives of substituted bicyclic compounds,their preparation and pharmaceutical compositions containing them

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2141705B (en) *	1983-06-20	1986-09-24	Erba Farmitalia	Imidazoles
EP0300675A3 (en) *	1987-07-21	1990-04-11	Merck Frosst Canada Inc.	Method for the improvement of cyclosporine therapy

1989
- 1989-06-23 GB GB898914525A patent/GB8914525D0/en active Pending
1990
- 1990-06-18 IL IL94765A patent/IL94765A0/xx unknown
- 1990-06-22 MY MYPI90001063A patent/MY105822A/en unknown
- 1990-06-22 ZA ZA904882A patent/ZA904882B/xx unknown
- 1990-06-22 PT PT94464A patent/PT94464A/pt not_active Application Discontinuation
- 1990-06-22 IE IE226690A patent/IE902266A1/en unknown
- 1990-06-25 HU HU905625A patent/HUT55989A/hu unknown
- 1990-06-25 JP JP2509951A patent/JPH04500375A/ja active Pending
- 1990-06-25 AU AU59584/90A patent/AU636898B2/en not_active Ceased
- 1990-06-25 CA CA002035032A patent/CA2035032A1/en not_active Abandoned
- 1990-06-25 EP EP90910697A patent/EP0433427A1/en not_active Withdrawn
- 1990-06-25 KR KR1019910700200A patent/KR920700669A/ko not_active Withdrawn
- 1990-06-25 WO PCT/EP1990/001010 patent/WO1991000102A1/en not_active Ceased

Also Published As

Publication number	Publication date
AU636898B2 (en)	1993-05-13
IE902266A1 (en)	1991-01-16
IL94765A0 (en)	1991-04-15
GB8914525D0 (en)	1989-08-09
PT94464A (pt)	1991-02-08
HUT55989A (en)	1991-07-29
WO1991000102A1 (en)	1991-01-10
EP0433427A1 (en)	1991-06-26
JPH04500375A (ja)	1992-01-23
KR920700669A (ko)	1992-08-10
HU905625D0 (en)	1991-06-28
ZA904882B (en)	1992-02-26
CA2035032A1 (en)	1990-12-24
AU5958490A (en)	1991-01-17

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