MY110182A - Novel phosphonosulfonate compounds, pharmaceutical compositions, and methods for treating abnormal calcium and phosphate metabolism - Google Patents

Novel phosphonosulfonate compounds, pharmaceutical compositions, and methods for treating abnormal calcium and phosphate metabolism

Info

Publication number
MY110182A
MY110182A MYPI93001059A MYPI19931059A MY110182A MY 110182 A MY110182 A MY 110182A MY PI93001059 A MYPI93001059 A MY PI93001059A MY PI19931059 A MYPI19931059 A MY PI19931059A MY 110182 A MY110182 A MY 110182A
Authority
MY
Malaysia
Prior art keywords
pharmaceutical compositions
abnormal calcium
novel
methods
treating abnormal
Prior art date
Application number
MYPI93001059A
Inventor
Michael Janusz John
David Francis Marion
George Anthony Nelson Dennis
Vincent Bayless Allan
Hallock Ebetino Frank
Mary Dansereau Susan (Nee Kaas)
Original Assignee
Procter & Gamble Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/055,809 external-priority patent/US5731299A/en
Application filed by Procter & Gamble Pharmaceuticals Inc filed Critical Procter & Gamble Pharmaceuticals Inc
Publication of MY110182A publication Critical patent/MY110182A/en

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

THE PRESENT INVENTION RELATES TO PHOSPHONSULFONATES AND PHARMACEUTICALLY-ACCEPTABLE SALTS AND ESTERS THEREOF, WHICH ARE USEFUL IN THE TREATMENT OF PREVENTION OF METABOLIC BONE DISORDERS CHARACTERIZED BY ABNORMAL CALCIUM AND PHOSPHATE METABOLISMS. THE COMPOUNDS OF THE PRESENT INVENTION HAVE PO3H2 AND SO3R GROUPS ATTACHED TO THE SAME CARBON ATOMS. R IS SELECTED FROM HYDROGEN, LOWER ALKYL, LOWER ACYLOXYALKYL, AMINOCARBONYLOXYALKYL, PIVALOYLOXYMETHYL, LACTONYL, LOWER ALKOXYACYLOXYALKYL, ALKOXYALKYL, CHOLINE AND ACYLAMINO ALKYL. ONE OF THE OTHER SUBSTITUENTS TO THE CARBON ATOM IS HYDROGEN, HALOGEN, MERCAPTO OR A DERIVATIVE THEREOF, A MERCAPTO-CONTAINING GROUP, AMINOHYDROXY OR SUBSTITUTED OR UNSUBSTITUTED ALKYL OF FROM 1 TO 8 CARBON ATOMS. THE REMAINING GROUP ATTACHED TO THE CENTRAL CARBON ATOM MAY BE ANY ONE OF A WIDE VARIETY OF ORGANIC MOIETIES.THE INVENTION ALSO INCLUDES PHARMACEUTICAL COMPOSITIONS SUITABLE FOR EXAMPLE IN TREATMENT OF OSTEOPOROSIS.
MYPI93001059A 1992-05-29 1993-05-28 Novel phosphonosulfonate compounds, pharmaceutical compositions, and methods for treating abnormal calcium and phosphate metabolism MY110182A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US89149092A 1992-05-29 1992-05-29
US89088692A 1992-05-29 1992-05-29
US89130992A 1992-05-29 1992-05-29
US08/055,809 US5731299A (en) 1992-05-29 1993-05-07 Phosphonosulfonate compounds, pharmaceutical compositions, and methods for treating abnormal calcium and phosphate metabolism

Publications (1)

Publication Number Publication Date
MY110182A true MY110182A (en) 1998-02-28

Family

ID=80001990

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI93001059A MY110182A (en) 1992-05-29 1993-05-28 Novel phosphonosulfonate compounds, pharmaceutical compositions, and methods for treating abnormal calcium and phosphate metabolism

Country Status (1)

Country Link
MY (1) MY110182A (en)

Similar Documents

Publication Publication Date Title
DE69330498D1 (en) PHOSPHONOCARBOXYLATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM
CS570287A2 (en) Process for preparing new derivatives of diphosphonic acid
CA2136820A1 (en) Thio-Substituted Nitrogen-Containing Heterocyclic Phosphonate Compounds for Treating Abnormal Calcium and Phosphate Metabolism
ZA884792B (en) Methylene phosphonoalkylphosphinates,pharmaceutical compositions,and methods for treating abnormal calcium and phosphate metabolism
RU94046117A (en) Sulfur-containing phosphonate compounds used for treatment of anomal calcium and phosphate metabolism, pharmaceutical compositions
BR0014615A (en) Derived from phosphonic acid which has inhibitory activity against carboxypeptidase b
MX9203567A (en) MONOCOLIN DERIVATIVE, PROCEDURE FOR ITS PREPARATION AND MEDICATION CONTAINED IN THIS DERIVATIVE.
GB9821670D0 (en) Plant extracts for the treatment of increased bone resorption
ATE169302T1 (en) PHOSPHONO SUPHONATE COMPOUNDS FOR THE TREATMENT OF ABNORMAL CALCIUM AND PHOSPATE METABOLISM
IL104229A (en) 2-saccharinylmethyl and 4, 5, 6, 7-tetrahydro-2-saccharinylmethyl phosphates phosphonates and phosphinates and pharmaceutical compositions containing them
DE69929218D1 (en) USE OF BISPHOSPHONATE DERIVATIVES FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF LAME
MX9303252A (en) NOVEL COMPOSITIONS OF CYCLIC PHOSPHONATE, THIO-SUBSTITUTES, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING ABNORMAL METABOLISM OF CALCIUM AND PHOSPHATE.
ATE2473T1 (en) TRIAZOLYL ETHER-CONTAINING PLANT GROWTH CONTROLLERS, METHOD OF MAKING THE AGENT AND METHODS OF PLANT GROWTH CONTROLLER.
DE69921346D1 (en) PLANT EXTRACTS FOR TREATING AN INCREASED BONE RESORPTION
RU94046139A (en) Quaternary nitrogen-containing phosphonate compounds for treatment of anomal calcium and phosphate metabolism, pharmaceutical composition
IL105836A0 (en) Quaternary nitrogen-containing phosphonate compounds and pharmaceutical compositions containing them
MY131438A (en) Novel phosphonocarboxylate compounds, pharmaceutical compositions and methods for treating abnormal calcium and phosphate metabolism