MY117168A - Composition and method for treating nonalcoholic steatohepatitis - Google Patents
Composition and method for treating nonalcoholic steatohepatitisInfo
- Publication number
- MY117168A MY117168A MYPI9805505A MY117168A MY 117168 A MY117168 A MY 117168A MY PI9805505 A MYPI9805505 A MY PI9805505A MY 117168 A MY117168 A MY 117168A
- Authority
- MY
- Malaysia
- Prior art keywords
- nonalcoholic steatohepatitis
- liver
- steatohepatitis
- damage
- formulations include
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 5
- 208000008338 non-alcoholic fatty liver disease Diseases 0.000 title abstract 5
- 206010053219 non-alcoholic steatohepatitis Diseases 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 2
- 206010061218 Inflammation Diseases 0.000 abstract 2
- 230000004054 inflammatory process Effects 0.000 abstract 2
- 210000004185 liver Anatomy 0.000 abstract 2
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 208000004930 Fatty Liver Diseases 0.000 abstract 1
- 206010016654 Fibrosis Diseases 0.000 abstract 1
- 206010019728 Hepatitis alcoholic Diseases 0.000 abstract 1
- 206010067125 Liver injury Diseases 0.000 abstract 1
- 238000009825 accumulation Methods 0.000 abstract 1
- 208000002353 alcoholic hepatitis Diseases 0.000 abstract 1
- 239000003963 antioxidant agent Substances 0.000 abstract 1
- 230000007882 cirrhosis Effects 0.000 abstract 1
- 208000019425 cirrhosis of liver Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000006378 damage Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 231100000234 hepatic damage Toxicity 0.000 abstract 1
- 239000000787 lecithin Substances 0.000 abstract 1
- 229940067606 lecithin Drugs 0.000 abstract 1
- 235000010445 lecithin Nutrition 0.000 abstract 1
- 210000005229 liver cell Anatomy 0.000 abstract 1
- 230000008818 liver damage Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 235000019156 vitamin B Nutrition 0.000 abstract 1
- 239000011720 vitamin B Substances 0.000 abstract 1
- 229940046001 vitamin b complex Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NONALCOHOLIC STEATOHEPATITIS (NASH) IS A DISEASE OF THE LIVER CHARACTERIZED BY INFLAMMATION AND DAMAGE TO THE LIVER CELLS. TYPICALLY, STEATOHEPATITIS INVOLVES INFLAMMATION OF THE LIVER RELATED TO FAT ACCUMULATION, AND MIMICS ALCOHOLIC HEPATITIS BUT IS OBSERVED IN PATIENTS WHO SELDOM OR NEVER CONSUME ALCOHOL. NONALCOHOLIC STEATOHEPATITIS CAN LEAD TO SERIOUS LIVER DAMAGE, AND ULTIMATELY CIRRHOSIS. THE PRESENT INVENTION PROVIDES METHODS AND COMPOSITIONS USEFUL FOR THE TREATMENT OR ALLEVIATION OF NONALCOHOLIC STEATOHEPATITIS AND THE PHARMACEUTICAL FORMULATIONS FOR THEIR ADMINISTRATION TO A HUMAN. SPECIFICALLY, COMPOSITIONS COMPRISED OF LECITHIN, ANTIOXIDANTS AND VITAMIN B COMPLEX ARE ADMINISTERED PARENTERALLY, MOST PREFERABLY BY ORAL ADMINISTRATION. SPECIFIC THERAPEUTIC FORMULATIONS INCLUDE ADMIXTURES OF THESE COMPOUNDSAND SPECIFIC DOSAGE FORMULATIONS INCLUDE DAILY ORAL ADMINISTRATIONS OF THESE COMPOUNDS IN TABLET OR POWDER FORMS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6732397P | 1997-12-05 | 1997-12-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY117168A true MY117168A (en) | 2004-05-31 |
Family
ID=22075227
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI9805505 MY117168A (en) | 1997-12-05 | 1998-12-04 | Composition and method for treating nonalcoholic steatohepatitis |
Country Status (4)
| Country | Link |
|---|---|
| AU (1) | AU1710299A (en) |
| MY (1) | MY117168A (en) |
| TW (1) | TW548105B (en) |
| WO (1) | WO1999029330A1 (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITRM20010763A1 (en) | 2001-12-21 | 2003-06-21 | Simone Claudio De | NEW LACTIC BACTERIA STOCK AND EDIBLE COMPOSITIONS, DRUGS AND VETERINARY PRODUCTS THAT CONTAIN IT. |
| JPWO2011158769A1 (en) * | 2010-06-17 | 2013-08-19 | 国立大学法人 千葉大学 | Non-alcoholic steatohepatitis detection and / or differentiation marker, non-alcoholic steatohepatitis detection and / or differentiation method, and kit used therefor |
| WO2014113695A1 (en) | 2013-01-18 | 2014-07-24 | Cornell University | Methods of treating diseases associated with high fat diet and vitamin a deficiency using retinoic acid receptor agonists |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5595982A (en) * | 1994-03-31 | 1997-01-21 | Harlmen Inc. | Equine nutritional supplement |
-
1998
- 1998-12-04 MY MYPI9805505 patent/MY117168A/en unknown
- 1998-12-04 WO PCT/US1998/025701 patent/WO1999029330A1/en not_active Ceased
- 1998-12-04 AU AU17102/99A patent/AU1710299A/en not_active Abandoned
- 1998-12-07 TW TW87120265A patent/TW548105B/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO1999029330A1 (en) | 1999-06-17 |
| WO1999029330A8 (en) | 1999-09-10 |
| AU1710299A (en) | 1999-06-28 |
| TW548105B (en) | 2003-08-21 |
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