MY117985A - Condensed-ring thiophene derivatives, their production and use. - Google Patents
Condensed-ring thiophene derivatives, their production and use.Info
- Publication number
- MY117985A MY117985A MYPI9603156A MY117985A MY 117985 A MY117985 A MY 117985A MY PI9603156 A MYPI9603156 A MY PI9603156A MY 117985 A MY117985 A MY 117985A
- Authority
- MY
- Malaysia
- Prior art keywords
- agent
- cancer
- homo
- hetero
- animals
- Prior art date
Links
- 150000003577 thiophenes Chemical class 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 abstract 7
- 241001465754 Metazoa Species 0.000 abstract 3
- 230000001419 dependent effect Effects 0.000 abstract 2
- 238000004770 highest occupied molecular orbital Methods 0.000 abstract 2
- 208000002874 Acne Vulgaris Diseases 0.000 abstract 1
- 201000000736 Amenorrhea Diseases 0.000 abstract 1
- 206010001928 Amenorrhoea Diseases 0.000 abstract 1
- 206010061692 Benign muscle neoplasm Diseases 0.000 abstract 1
- 206010004446 Benign prostatic hyperplasia Diseases 0.000 abstract 1
- 206010006187 Breast cancer Diseases 0.000 abstract 1
- 208000026310 Breast neoplasm Diseases 0.000 abstract 1
- 201000009273 Endometriosis Diseases 0.000 abstract 1
- 239000000579 Gonadotropin-Releasing Hormone Substances 0.000 abstract 1
- 201000004458 Myoma Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 208000007913 Pituitary Neoplasms Diseases 0.000 abstract 1
- 201000005746 Pituitary adenoma Diseases 0.000 abstract 1
- 206010061538 Pituitary tumour benign Diseases 0.000 abstract 1
- 206010036618 Premenstrual syndrome Diseases 0.000 abstract 1
- 206010060862 Prostate cancer Diseases 0.000 abstract 1
- 208000004403 Prostatic Hyperplasia Diseases 0.000 abstract 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 abstract 1
- 101000857870 Squalus acanthias Gonadoliberin Proteins 0.000 abstract 1
- 206010000496 acne Diseases 0.000 abstract 1
- 231100000540 amenorrhea Toxicity 0.000 abstract 1
- 230000003042 antagnostic effect Effects 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 201000010881 cervical cancer Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003433 contraceptive agent Substances 0.000 abstract 1
- 230000002254 contraceptive effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000001158 estrous effect Effects 0.000 abstract 1
- 230000035558 fertility Effects 0.000 abstract 1
- 239000003163 gonadal steroid hormone Substances 0.000 abstract 1
- XLXSAKCOAKORKW-AQJXLSMYSA-N gonadorelin Chemical compound C([C@@H](C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1[C@@H](CCC1)C(=O)NCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H](CC=1N=CNC=1)NC(=O)[C@H]1NC(=O)CC1)C1=CC=C(O)C=C1 XLXSAKCOAKORKW-AQJXLSMYSA-N 0.000 abstract 1
- 229940035638 gonadotropin-releasing hormone Drugs 0.000 abstract 1
- 239000005556 hormone Substances 0.000 abstract 1
- 229940088597 hormone Drugs 0.000 abstract 1
- 230000036512 infertility Effects 0.000 abstract 1
- 208000000509 infertility Diseases 0.000 abstract 1
- 231100000535 infertility Toxicity 0.000 abstract 1
- 235000013372 meat Nutrition 0.000 abstract 1
- 230000027758 ovulation cycle Effects 0.000 abstract 1
- 208000021310 pituitary gland adenoma Diseases 0.000 abstract 1
- 201000010065 polycystic ovary syndrome Diseases 0.000 abstract 1
- 208000006155 precocious puberty Diseases 0.000 abstract 1
- 230000035935 pregnancy Effects 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
- 230000001739 rebound effect Effects 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
- 210000004291 uterus Anatomy 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
A GONADOTROPIN-RELEASING HORMONE ANTAGONISTIC COMPOSITION, WHICH COMPRISES AN OPTIONALLY SUBSTITUTED CONDENSED-BICYCLIC COMPOUND CO.NSISTING OF A HOMO OR HETERO 5 TO 7 MEMBERED RING AND A HOMO OR HETERO 5 TO 7 MEMBERED RING IS EFFECTIVE AS A PROPYLACTIC OR THERAPEUTIC AGENT FOR THE PREVENTION OR TREATMENT OF SEVERAL HORMONE DEPENDENT DISEASES, FOR EXAMPLE, A SEX HORMONE DEPENDENT CANCER (E.G. PROSTATIC CANCER, CANCER OF UTERINE CERVIX, BREAST CANCER, PITUITARY ADENOMA), BENIGN PROSTATIC HYPERTROPHY, MYOMA OF THE UTERUS, ENDOMETRIOSIS, PRECOCIOUS PUBERTY, AMENORRHEA, PREMENSTRUAL SYNDROME, POLYCYSTIC OVARY SYNDROME AND ACNE VULGARIS; IS EFFECTIVE AS A FERTILITY CONTROLLING AGENT IN BOTH SEXES (E.G. A PREGNANCY CONTROLLING AGENT AND A MENSTRUAL CYCLE CONTROLLING AGENT); CAN BE USED AS A CONTRACEPTIVE OF MALE OR FEMALE, AS AN OVULATION-INDUCING AGENT OF FEMALE; CAN BE USED AS AN INFERTILITY TREATING AGENT BY USING A REBOUND EFFECT OWING TO A STOPPAGE OF ADMINISTRATION THEREOF; IS USEFUL AS MODULATING ESTROUS CYCLES IN ANIMALS IN THE FIELD OF ANIMAL HUSBANDRY, .AS AN AGENT FRO IMPROVING THE QUALITY OF EDIBLE MEAT OR PROMOTING THE GROWTH OF ANIMALS; IS USEFUL AS AN AGENT OF SPAWNING PROMOTION IN FISH.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MYPI9603156 MY117985A (en) | 1996-08-01 | 1996-08-01 | Condensed-ring thiophene derivatives, their production and use. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MYPI9603156 MY117985A (en) | 1996-08-01 | 1996-08-01 | Condensed-ring thiophene derivatives, their production and use. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY117985A true MY117985A (en) | 2004-08-30 |
Family
ID=46851702
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI9603156 MY117985A (en) | 1996-08-01 | 1996-08-01 | Condensed-ring thiophene derivatives, their production and use. |
Country Status (1)
| Country | Link |
|---|---|
| MY (1) | MY117985A (en) |
-
1996
- 1996-08-01 MY MYPI9603156 patent/MY117985A/en unknown
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