MY133842A - Sodium-hydrogen exchanger type 1 inhibitor. - Google Patents

Sodium-hydrogen exchanger type 1 inhibitor.

Info

Publication number
MY133842A
MY133842A MYPI20011977A MYPI20011977A MY133842A MY 133842 A MY133842 A MY 133842A MY PI20011977 A MYPI20011977 A MY PI20011977A MY PI20011977 A MYPI20011977 A MY PI20011977A MY 133842 A MY133842 A MY 133842A
Authority
MY
Malaysia
Prior art keywords
inhibitor
sodium
exchanger type
hydrogen exchanger
nhe
Prior art date
Application number
MYPI20011977A
Inventor
Guzman-Perez Angel
David Cox Eric
George Chen Weichao
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of MY133842A publication Critical patent/MY133842A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preventing Corrosion Or Incrustation Of Metals (AREA)
  • Treatment Of Water By Ion Exchange (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

NHE-1 INHIBITOR, METHODS OF USING THE NHE-1 INHIBITOR AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE NHE-1 INHIBITOR. THE NHE-1 INHIBITOR IS USEFUL FOR THE REDUCTION OF TISSUE A DAMAGE RESULTING FROM TISSUE ISCHEMIA.
MYPI20011977A 2000-04-28 2001-04-26 Sodium-hydrogen exchanger type 1 inhibitor. MY133842A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US20043200P 2000-04-28 2000-04-28

Publications (1)

Publication Number Publication Date
MY133842A true MY133842A (en) 2007-11-30

Family

ID=22741697

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI20011977A MY133842A (en) 2000-04-28 2001-04-26 Sodium-hydrogen exchanger type 1 inhibitor.

Country Status (40)

Country Link
EP (1) EP1276737A1 (en)
JP (1) JP2003531900A (en)
KR (1) KR20020093079A (en)
CN (1) CN1225466C (en)
AP (1) AP2002002651A0 (en)
AR (1) AR028375A1 (en)
AU (1) AU2001235896A1 (en)
BG (1) BG107139A (en)
BR (1) BR0110268A (en)
CA (1) CA2407535A1 (en)
CO (1) CO5221125A1 (en)
CR (1) CR6797A (en)
CZ (1) CZ20023408A3 (en)
DZ (1) DZ3310A1 (en)
EA (1) EA004882B1 (en)
EE (1) EE200200615A (en)
GT (1) GT200100064A (en)
HN (1) HN2001000042A (en)
HR (1) HRP20020851A2 (en)
HU (1) HUP0300651A2 (en)
IL (1) IL152075A0 (en)
IS (2) IS6567A (en)
MA (1) MA26897A1 (en)
MX (1) MXPA02010600A (en)
MY (1) MY133842A (en)
NO (1) NO20025132L (en)
NZ (1) NZ521348A (en)
OA (1) OA12256A (en)
PA (1) PA8513301A1 (en)
PE (1) PE20011270A1 (en)
PL (1) PL357765A1 (en)
SK (1) SK14872002A3 (en)
SV (1) SV2002000418A (en)
TN (1) TNSN01065A1 (en)
TR (1) TR200202439T2 (en)
UA (1) UA73348C2 (en)
UY (1) UY26680A1 (en)
WO (1) WO2001083470A1 (en)
YU (1) YU79602A (en)
ZA (1) ZA200208605B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1355899A1 (en) * 2001-01-31 2003-10-29 Pfizer Products Inc. Ethanolates of sodium-hydrogen exchanger type-1 inhibitor
CA2469305A1 (en) * 2001-12-19 2003-06-26 Frank Robert Busch Methods for preparing sodium-hydrogen exchanger type-1 inhibitors
WO2003092694A1 (en) * 2002-05-02 2003-11-13 Pfizer Products Inc. Treatment of diabetes and diabetic complications with nhe-1 inhibitors
FR2840302B1 (en) * 2002-06-03 2004-07-16 Aventis Pharma Sa ISOINDOLONE DERIVATIVES, PREPARATION METHOD AND INTERMEDIARY THEREOF AS MEDICAMENTS AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME
ES2220185B1 (en) * 2002-07-16 2006-04-01 Consejo Sup. De Investig. Cientificas NEW INHIBITOR PEPTIDE OF THE NA + / H + EXCHANGER (PINHE), AND ITS APPLICATIONS.
MXPA05008612A (en) * 2003-02-14 2005-12-05 Smithkline Beecham Corp Novel compounds.
RU2518741C1 (en) * 2013-03-22 2014-06-10 Федеральное государственное автономное образовательное учреждение высшего профессионального образования "ЮЖНЫЙ ФЕДЕРАЛЬНЫЙ УНИВЕРСИТЕТ" MEDICATION, INHIBITING Na+/H+-EXCHANGE, AND HALOGENIDES OF 1-DIALKYLAMINOETHYL-3-[SUBSTITUTED(DISUBSTITUTED)PHENACYL]-2-AMINOBENZIMIDAZOLIUM

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU46200A (en) * 1998-02-27 2003-02-28 Pfizer Products Inc. N(substituted five-membered di-or triaza diunsaturated ring) carbonyl/ guanidine derivatives for the treatment of ischemia

Also Published As

Publication number Publication date
AP2002002651A0 (en) 2002-12-31
BR0110268A (en) 2003-12-30
BG107139A (en) 2003-07-31
HRP20020851A2 (en) 2005-02-28
EA004882B1 (en) 2004-08-26
JP2003531900A (en) 2003-10-28
YU79602A (en) 2006-05-25
GT200100064A (en) 2002-03-22
IL152075A0 (en) 2003-05-29
CR6797A (en) 2004-05-17
MXPA02010600A (en) 2003-03-10
PL357765A1 (en) 2004-07-26
CN1426404A (en) 2003-06-25
IS6567A (en) 2002-09-24
AU2001235896A1 (en) 2001-11-12
CO5221125A1 (en) 2002-11-28
MA26897A1 (en) 2004-12-20
NO20025132D0 (en) 2002-10-25
PA8513301A1 (en) 2003-09-05
CZ20023408A3 (en) 2004-01-14
UY26680A1 (en) 2001-12-28
EA200201023A1 (en) 2003-02-27
AR028375A1 (en) 2003-05-07
NZ521348A (en) 2004-09-24
EP1276737A1 (en) 2003-01-22
CA2407535A1 (en) 2001-11-08
DZ3310A1 (en) 2001-11-07
NO20025132L (en) 2002-12-12
PE20011270A1 (en) 2001-12-12
KR20020093079A (en) 2002-12-12
SV2002000418A (en) 2002-07-03
SK14872002A3 (en) 2004-03-02
UA73348C2 (en) 2005-07-15
CN1225466C (en) 2005-11-02
HN2001000042A (en) 2001-07-09
TR200202439T2 (en) 2003-02-21
WO2001083470A1 (en) 2001-11-08
HUP0300651A2 (en) 2003-07-28
IS6588A (en) 2002-10-21
ZA200208605B (en) 2003-10-24
EE200200615A (en) 2004-04-15
OA12256A (en) 2003-11-06
TNSN01065A1 (en) 2005-11-10

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