MY133842A - Sodium-hydrogen exchanger type 1 inhibitor. - Google Patents
Sodium-hydrogen exchanger type 1 inhibitor.Info
- Publication number
- MY133842A MY133842A MYPI20011977A MYPI20011977A MY133842A MY 133842 A MY133842 A MY 133842A MY PI20011977 A MYPI20011977 A MY PI20011977A MY PI20011977 A MYPI20011977 A MY PI20011977A MY 133842 A MY133842 A MY 133842A
- Authority
- MY
- Malaysia
- Prior art keywords
- inhibitor
- sodium
- exchanger type
- hydrogen exchanger
- nhe
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title abstract 5
- 102000052126 Sodium-Hydrogen Exchangers Human genes 0.000 title 1
- 108091006672 Sodium–hydrogen antiporter Proteins 0.000 title 1
- 102100030980 Sodium/hydrogen exchanger 1 Human genes 0.000 abstract 4
- 108010093115 growth factor-activatable Na-H exchanger NHE-1 Proteins 0.000 abstract 4
- 208000028867 ischemia Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Treatment Of Water By Ion Exchange (AREA)
- Preventing Corrosion Or Incrustation Of Metals (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
NHE-1 INHIBITOR, METHODS OF USING THE NHE-1 INHIBITOR AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE NHE-1 INHIBITOR. THE NHE-1 INHIBITOR IS USEFUL FOR THE REDUCTION OF TISSUE A DAMAGE RESULTING FROM TISSUE ISCHEMIA.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20043200P | 2000-04-28 | 2000-04-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY133842A true MY133842A (en) | 2007-11-30 |
Family
ID=22741697
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI20011977A MY133842A (en) | 2000-04-28 | 2001-04-26 | Sodium-hydrogen exchanger type 1 inhibitor. |
Country Status (40)
| Country | Link |
|---|---|
| EP (1) | EP1276737A1 (en) |
| JP (1) | JP2003531900A (en) |
| KR (1) | KR20020093079A (en) |
| CN (1) | CN1225466C (en) |
| AP (1) | AP2002002651A0 (en) |
| AR (1) | AR028375A1 (en) |
| AU (1) | AU2001235896A1 (en) |
| BG (1) | BG107139A (en) |
| BR (1) | BR0110268A (en) |
| CA (1) | CA2407535A1 (en) |
| CO (1) | CO5221125A1 (en) |
| CR (1) | CR6797A (en) |
| CZ (1) | CZ20023408A3 (en) |
| DZ (1) | DZ3310A1 (en) |
| EA (1) | EA004882B1 (en) |
| EE (1) | EE200200615A (en) |
| GT (1) | GT200100064A (en) |
| HN (1) | HN2001000042A (en) |
| HR (1) | HRP20020851A2 (en) |
| HU (1) | HUP0300651A2 (en) |
| IL (1) | IL152075A0 (en) |
| IS (2) | IS6567A (en) |
| MA (1) | MA26897A1 (en) |
| MX (1) | MXPA02010600A (en) |
| MY (1) | MY133842A (en) |
| NO (1) | NO20025132L (en) |
| NZ (1) | NZ521348A (en) |
| OA (1) | OA12256A (en) |
| PA (1) | PA8513301A1 (en) |
| PE (1) | PE20011270A1 (en) |
| PL (1) | PL357765A1 (en) |
| SK (1) | SK14872002A3 (en) |
| SV (1) | SV2002000418A (en) |
| TN (1) | TNSN01065A1 (en) |
| TR (1) | TR200202439T2 (en) |
| UA (1) | UA73348C2 (en) |
| UY (1) | UY26680A1 (en) |
| WO (1) | WO2001083470A1 (en) |
| YU (1) | YU79602A (en) |
| ZA (1) | ZA200208605B (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1479737A (en) * | 2001-01-31 | 2004-03-03 | �Ʒ� | Sodium-proton exchanger protein type 1 inhibitor ethanolate |
| EP1456181A1 (en) * | 2001-12-19 | 2004-09-15 | Pfizer Products Inc. | Methods for preparing sodium-hydrogen exchanger type-1 inhibitors |
| MXPA04008646A (en) * | 2002-05-02 | 2004-12-06 | Pfizer Prod Inc | Treatment of diabetes and diabetic complications with nhe-1 inhibitors. |
| FR2840302B1 (en) * | 2002-06-03 | 2004-07-16 | Aventis Pharma Sa | ISOINDOLONE DERIVATIVES, PREPARATION METHOD AND INTERMEDIARY THEREOF AS MEDICAMENTS AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME |
| ES2220185B1 (en) * | 2002-07-16 | 2006-04-01 | Consejo Sup. De Investig. Cientificas | NEW INHIBITOR PEPTIDE OF THE NA + / H + EXCHANGER (PINHE), AND ITS APPLICATIONS. |
| PL378111A1 (en) * | 2003-02-14 | 2006-03-06 | Smithkline Beecham Corporation | Novel compounds |
| RU2518741C1 (en) * | 2013-03-22 | 2014-06-10 | Федеральное государственное автономное образовательное учреждение высшего профессионального образования "ЮЖНЫЙ ФЕДЕРАЛЬНЫЙ УНИВЕРСИТЕТ" | MEDICATION, INHIBITING Na+/H+-EXCHANGE, AND HALOGENIDES OF 1-DIALKYLAMINOETHYL-3-[SUBSTITUTED(DISUBSTITUTED)PHENACYL]-2-AMINOBENZIMIDAZOLIUM |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT1056729E (en) * | 1998-02-27 | 2005-04-29 | Pfizer Prod Inc | DERIVATIVES OF N- [CYCLE DI- OR TRI-AZA DI-INSATURATE OF FIVE SUBSTITUTED MEMBERS] CARBONYL] GUANIDINE FOR THE TREATMENT OF ISCHEMIA |
-
2001
- 2001-02-28 EP EP01908037A patent/EP1276737A1/en not_active Withdrawn
- 2001-02-28 NZ NZ521348A patent/NZ521348A/en unknown
- 2001-02-28 AU AU2001235896A patent/AU2001235896A1/en not_active Abandoned
- 2001-02-28 PL PL01357765A patent/PL357765A1/en not_active Application Discontinuation
- 2001-02-28 MX MXPA02010600A patent/MXPA02010600A/en active IP Right Grant
- 2001-02-28 EA EA200201023A patent/EA004882B1/en not_active IP Right Cessation
- 2001-02-28 CZ CZ20023408A patent/CZ20023408A3/en unknown
- 2001-02-28 TR TR2002/02439T patent/TR200202439T2/en unknown
- 2001-02-28 CN CNB018087256A patent/CN1225466C/en not_active Expired - Fee Related
- 2001-02-28 IL IL15207501A patent/IL152075A0/en unknown
- 2001-02-28 KR KR1020027014355A patent/KR20020093079A/en not_active Abandoned
- 2001-02-28 CA CA002407535A patent/CA2407535A1/en not_active Abandoned
- 2001-02-28 WO PCT/IB2001/000277 patent/WO2001083470A1/en not_active Ceased
- 2001-02-28 SK SK1487-2002A patent/SK14872002A3/en unknown
- 2001-02-28 YU YUP-796/02A patent/YU79602A/en unknown
- 2001-02-28 HU HU0300651A patent/HUP0300651A2/en unknown
- 2001-02-28 OA OA1200200331A patent/OA12256A/en unknown
- 2001-02-28 AP APAP/P/2002/002651A patent/AP2002002651A0/en unknown
- 2001-02-28 BR BR0110268-0A patent/BR0110268A/en not_active IP Right Cessation
- 2001-02-28 HR HR20020851A patent/HRP20020851A2/en not_active Application Discontinuation
- 2001-02-28 UA UA2002108497A patent/UA73348C2/en unknown
- 2001-02-28 JP JP2001580898A patent/JP2003531900A/en active Pending
- 2001-02-28 EE EEP200200615A patent/EE200200615A/en unknown
- 2001-02-28 DZ DZ013310A patent/DZ3310A1/en active
- 2001-03-06 HN HN2001000042A patent/HN2001000042A/en unknown
- 2001-03-12 PA PA20018513301A patent/PA8513301A1/en unknown
- 2001-04-20 GT GT200100064A patent/GT200100064A/en unknown
- 2001-04-24 UY UY26680A patent/UY26680A1/en not_active Application Discontinuation
- 2001-04-26 AR ARP010101970A patent/AR028375A1/en unknown
- 2001-04-26 MY MYPI20011977A patent/MY133842A/en unknown
- 2001-04-26 PE PE2001000376A patent/PE20011270A1/en not_active Application Discontinuation
- 2001-04-27 SV SV2001000418A patent/SV2002000418A/en not_active Application Discontinuation
- 2001-04-27 TN TNTNSN01065A patent/TNSN01065A1/en unknown
- 2001-04-27 CO CO01032977A patent/CO5221125A1/en not_active Application Discontinuation
-
2002
- 2002-09-23 BG BG107139A patent/BG107139A/en unknown
- 2002-09-24 IS IS6567A patent/IS6567A/en unknown
- 2002-10-18 MA MA26875A patent/MA26897A1/en unknown
- 2002-10-18 CR CR6797A patent/CR6797A/en not_active Application Discontinuation
- 2002-10-21 IS IS6588A patent/IS6588A/en unknown
- 2002-10-24 ZA ZA200208605A patent/ZA200208605B/en unknown
- 2002-10-25 NO NO20025132A patent/NO20025132L/en not_active Application Discontinuation
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