MY134311A - Medicament with delayed active constituent release containing 1-dimethylamino-3-(3-methoxyphenyl)-2-methylpentan-3-ol - Google Patents
Medicament with delayed active constituent release containing 1-dimethylamino-3-(3-methoxyphenyl)-2-methylpentan-3-olInfo
- Publication number
- MY134311A MY134311A MYPI20031965A MYPI20031965A MY134311A MY 134311 A MY134311 A MY 134311A MY PI20031965 A MYPI20031965 A MY PI20031965A MY PI20031965 A MYPI20031965 A MY PI20031965A MY 134311 A MY134311 A MY 134311A
- Authority
- MY
- Malaysia
- Prior art keywords
- methylpentan
- methoxyphenyl
- dimethylamino
- released
- hours
- Prior art date
Links
- PZNRRUTVGXCKFC-UHFFFAOYSA-N 1-(dimethylamino)-3-(3-methoxyphenyl)-2-methylpentan-3-ol Chemical compound CN(C)CC(C)C(O)(CC)C1=CC=CC(OC)=C1 PZNRRUTVGXCKFC-UHFFFAOYSA-N 0.000 title abstract 9
- 239000000470 constituent Substances 0.000 title abstract 4
- 230000003111 delayed effect Effects 0.000 title abstract 3
- 239000003814 drug Substances 0.000 title 1
- 239000011159 matrix material Substances 0.000 abstract 2
- 238000004090 dissolution Methods 0.000 abstract 1
- 229920001477 hydrophilic polymer Polymers 0.000 abstract 1
- 229920001600 hydrophobic polymer Polymers 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
THE INVENTION RELATES TO A PHARMACEUTICAL FORMULATION WITH DELAYED RELEASE OF ACTIVE CONSTITUENT, WHICH CONTAINS 1- DIMETHYLAMINO-3-(3-METHOXYPHENYL)-2-METHYLPENTAN-3-OL OR ONE OF ITS PHARMACEUTICALLY ACCEPTABLE SALTS IN A MATRIX, WITH DELAYED RELEASE OF ACTIVE CONSTITUENT, WHEREIN THE MATRIX CONTAINS 1 TO 80 WT.% OF ONE OR MORE HYDROPHILIC OR HYDROPHOBIC POLYMERS AS PHARMACEUTICALLY ACCEPTABLE MATRIX- FORMING AGENTS AND HAS THE FOLLOWING IN VITRO DISSOLUTION RATE: 3-35 WT.% (REFERRED TO 100 WT.% OF ACTIVE CONSTITUENT) OF 1 DIMETHYLAMINO-3-(3-METHOXYPHENYL)-2- METHYLPENTAN-3-OL RELEASED AFTER 0.5 HOUR, 5-50 WT.% OF 1- DIMETHYLAMINO-3-(3-METHOXYPHENYL)-2-METHYLPENTAN-3-OL RELEASED AFTER 1 HOUR, 10-75 WT.% OF 1-DIMETHYLAMINO-3-(3-METHOXYPHENYL)-2-METHYLPENTAN-3-OL RELEASED AFTER 2 HOURS, 15-82 WT.% OF 1-DIMETHYLAMINO-3-(3-METHOXYPHENYL)-2- METHYLPENTAN-3-OL RELEASED AFTER 3 HOURS, 30-97 WT.% OF 1- DIMETHYLAMINO-3-(3-METHOXYPHENYL)-2-METHYLPENTAN-3-OL RELEASED AFTER 6 HOURS, MORE THAN 50 WT.% OF 1- DIMETHYLAMINO-3-(3-METHOXYPHENYL)-2-METHYLPENTAN-3-OL RELEASED AFTER 12 HOURS, MORE THAN 70 WT.% OF 1- DIMETHYLAMINO-3-(3-METHOXYPHENYL)-2-METHYLPENTAN-3-OL RELEASED AFTER 18 HOURS, AND MORE THAN 80 WT.% OF 1- DIMETHYLAMINO-3-(3-METHOXYPHENYL)-2-METHYLPENTAN-3-O1 RELEASED AFTER 24 HOURS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10224108A DE10224108A1 (en) | 2002-05-29 | 2002-05-29 | 1-Dimethylamino-3- (3-methoxyphenyl) -2-methylpentan-3-ol containing sustained-release drug |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY134311A true MY134311A (en) | 2007-12-31 |
Family
ID=29557413
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI20031965A MY134311A (en) | 2002-05-29 | 2003-05-28 | Medicament with delayed active constituent release containing 1-dimethylamino-3-(3-methoxyphenyl)-2-methylpentan-3-ol |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP1507519B1 (en) |
| JP (1) | JP5459818B2 (en) |
| AR (1) | AR039900A1 (en) |
| AT (1) | ATE326218T1 (en) |
| AU (1) | AU2003238397A1 (en) |
| CA (1) | CA2488220C (en) |
| DE (2) | DE10224108A1 (en) |
| DK (1) | DK1507519T3 (en) |
| ES (1) | ES2263976T3 (en) |
| MY (1) | MY134311A (en) |
| PE (1) | PE20040529A1 (en) |
| PL (1) | PL218397B1 (en) |
| PT (1) | PT1507519E (en) |
| WO (1) | WO2003099267A1 (en) |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4389393A (en) * | 1982-03-26 | 1983-06-21 | Forest Laboratories, Inc. | Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose |
| US5032406A (en) * | 1989-02-21 | 1991-07-16 | Norwich Eaton Pharmaceuticals, Inc. | Dual-action tablet |
| US5582837A (en) * | 1992-03-25 | 1996-12-10 | Depomed, Inc. | Alkyl-substituted cellulose-based sustained-release oral drug dosage forms |
| JPH06172161A (en) * | 1992-12-10 | 1994-06-21 | Shin Etsu Chem Co Ltd | Sustained release tablets |
| DE4329794C2 (en) * | 1993-09-03 | 1997-09-18 | Gruenenthal Gmbh | Tramadol salt-containing drugs with delayed release |
| DE4426245A1 (en) * | 1994-07-23 | 1996-02-22 | Gruenenthal Gmbh | 1-phenyl-3-dimethylamino-propane compounds with pharmacological activity |
| JPH1017497A (en) * | 1996-07-02 | 1998-01-20 | Takeda Chem Ind Ltd | Sustained release pharmaceutical preparation and its production |
| DE10059412A1 (en) * | 2000-11-30 | 2002-06-13 | Gruenenthal Gmbh | Use of 1-phenyl-3-dimethylamino-propane compounds for the treatment of urinary incontinence |
| DE10146275A1 (en) * | 2001-09-18 | 2003-04-24 | Gruenenthal Gmbh | Combination of selected opioids with muscarinic antagonists for the treatment of urinary incontinence |
-
2002
- 2002-05-29 DE DE10224108A patent/DE10224108A1/en not_active Withdrawn
-
2003
- 2003-05-26 PT PT03732464T patent/PT1507519E/en unknown
- 2003-05-26 DE DE50303372T patent/DE50303372D1/en not_active Expired - Lifetime
- 2003-05-26 PL PL374186A patent/PL218397B1/en unknown
- 2003-05-26 ES ES03732464T patent/ES2263976T3/en not_active Expired - Lifetime
- 2003-05-26 AU AU2003238397A patent/AU2003238397A1/en not_active Abandoned
- 2003-05-26 CA CA2488220A patent/CA2488220C/en not_active Expired - Fee Related
- 2003-05-26 DK DK03732464T patent/DK1507519T3/en active
- 2003-05-26 AT AT03732464T patent/ATE326218T1/en not_active IP Right Cessation
- 2003-05-26 JP JP2004506791A patent/JP5459818B2/en not_active Expired - Fee Related
- 2003-05-26 EP EP03732464A patent/EP1507519B1/en not_active Expired - Lifetime
- 2003-05-26 WO PCT/EP2003/005488 patent/WO2003099267A1/en not_active Ceased
- 2003-05-28 MY MYPI20031965A patent/MY134311A/en unknown
- 2003-05-29 PE PE2003000521A patent/PE20040529A1/en not_active Application Discontinuation
- 2003-05-29 AR ARP030101884A patent/AR039900A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1507519A1 (en) | 2005-02-23 |
| EP1507519B1 (en) | 2006-05-17 |
| PE20040529A1 (en) | 2004-08-24 |
| WO2003099267A1 (en) | 2003-12-04 |
| JP2005534640A (en) | 2005-11-17 |
| AR039900A1 (en) | 2005-03-09 |
| PL218397B1 (en) | 2014-11-28 |
| CA2488220A1 (en) | 2003-12-04 |
| DE10224108A1 (en) | 2004-01-29 |
| ATE326218T1 (en) | 2006-06-15 |
| PT1507519E (en) | 2006-08-31 |
| PL374186A1 (en) | 2005-10-03 |
| AU2003238397A1 (en) | 2003-12-12 |
| CA2488220C (en) | 2011-02-01 |
| DE50303372D1 (en) | 2006-06-22 |
| JP5459818B2 (en) | 2014-04-02 |
| ES2263976T3 (en) | 2006-12-16 |
| DK1507519T3 (en) | 2006-08-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MY127797A (en) | 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)phenol-containing pharmaceutical composition with slow release of active indgredient | |
| EA200700049A1 (en) | PREPARATIVE FORMS OF ORAL MEDICINAL FORMS OF MEMANTINE WITH MODIFIED SURVIVAL | |
| WO2008107149A3 (en) | Pharmaceutical form with impeded abuse | |
| EP2266542A3 (en) | Controlled release nanoparticulate compositions | |
| WO2007048219A3 (en) | Sustained drug release composition | |
| RU2005115855A (en) | COMPOSITION OF TRAMADOL PROLONGED BY RELEASE WITH 24 HOUR ACTION | |
| ATE396712T1 (en) | PHARMACEUTICAL PREPARATION FOR MODIFIED RELEASE | |
| PE20030399A1 (en) | FORMS OF ADMINISTRATION OF PROPIVERINE OR ITS PHARMACEUTICALLY ACCEPTABLE SALTS WITH PROLONGED RELEASE OF THE ACTIVE SUBSTANCE | |
| AU2003274681A1 (en) | Dosage form comprising high dose high soluble active ingredient as modified release and low dose active ingredient as immediate release | |
| BR0107874A (en) | Pharmaceutical implant for controllably releasing a drug, method for controllably releasing a drug in an individual, and method for preparing the implant | |
| HUP0003405A2 (en) | Controlled release of drugs delivered by sublingual or buccal adminisration | |
| MY148475A (en) | Controlled release preparations comprising tramadol and topiramate | |
| MX2008000099A (en) | Modified release pharmaceutical compositions on the basis of two polymers and processes thereof. | |
| WO2001047498A3 (en) | Hydrogel-driven layered drug dosage form comprising sertraline | |
| DE60124294D1 (en) | PROINSULIN C-PEPTIDE CONTAINING MEDICINE PREPARATION WITH DELAYED ACTIVE INGREDIENT RELEASE | |
| MX2007015480A (en) | Solid dosage formulations of narcotic drugs having improved buccal adsorption. | |
| PE20001414A1 (en) | PROCEDURE FOR PREPARING BALLOONS CONTAINING 50% BY WEIGHT OR MORE OF A PHARMACEUTICAL SUBSTANCE OF WATER SOLUBILITY | |
| WO2005009329A3 (en) | Medicament containing 6-dimethylaminomethyl-1-(3-methoxy-phenyl)-cyclohexane-1,3-diol with delayed release of active ingredients | |
| BR0311327A (en) | Oxcarbazepine-containing pharmaceutical composition with sustained release of an active ingredient | |
| IL174830A0 (en) | Pellets containing venlafaxine hydrochloride, pharmaceutical compositions comprising them and processes for their preparation | |
| CA2415154A1 (en) | Modified release formulations of selective serotonin re-uptake inhibitors | |
| ATE476997T1 (en) | COMPOSITION AND DOSAGE FORM COMPRISING A SOLID OR SEMI-SOLID MATRIX | |
| WO2006008173A3 (en) | Pharmaceutical formulations for inhalation | |
| WO2009125944A3 (en) | Pharmaceutical preparation containing non-dihydropyridine calcium channel blocker and angiotensin-2 receptor blocker | |
| MY134311A (en) | Medicament with delayed active constituent release containing 1-dimethylamino-3-(3-methoxyphenyl)-2-methylpentan-3-ol |