MY136047A - Novel potentiating compounds - Google Patents
Novel potentiating compoundsInfo
- Publication number
- MY136047A MY136047A MYPI20034101A MY136047A MY 136047 A MY136047 A MY 136047A MY PI20034101 A MYPI20034101 A MY PI20034101A MY 136047 A MY136047 A MY 136047A
- Authority
- MY
- Malaysia
- Prior art keywords
- novel
- compounds
- paclitaxel
- potentiating compounds
- novel compounds
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 5
- 230000003389 potentiating effect Effects 0.000 title 1
- 229930012538 Paclitaxel Natural products 0.000 abstract 2
- 238000009472 formulation Methods 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 229960001592 paclitaxel Drugs 0.000 abstract 2
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 231100000433 cytotoxic Toxicity 0.000 abstract 1
- 230000001472 cytotoxic effect Effects 0.000 abstract 1
- 230000001747 exhibiting effect Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Landscapes
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
THIS INVENTION RELATES TO NOVEL COMPOUNDS, CAPABLE OF POLENTIATING THE EFFICACY OF THERAPEUTICALLY ACTIVE COMPOUNDS, FOR EXAMPLE CYTOTOXIC COMPOUNDS USED IN THE TREATMENT OF CANCER. THE NOVEL COMPOUNDS HAVE BEEN SHOWN TO INCREASE THE PHARMACOLOGICAL ACTIVITY OF A CONVENTIONAL PACLITAXEL FORMULATION AND TO MAKE IT POSSIBLE TO MANUFACTURE A NEW FORMULATION OF PACLITAXEL EXHIBITING IMPROVED SOLUBILITY, IMPROVED STORAGE PROPERTIES, AND INCREASED THERAPEUTIC EFFICACY AS SHOWN IN THE ENCLOSED EXAMPLES. (FORMULA I,II,III,IV,V,VI)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MYPI20034101 MY136047A (en) | 2003-10-28 | 2003-10-28 | Novel potentiating compounds |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MYPI20034101 MY136047A (en) | 2003-10-28 | 2003-10-28 | Novel potentiating compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY136047A true MY136047A (en) | 2008-08-29 |
Family
ID=45891158
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI20034101 MY136047A (en) | 2003-10-28 | 2003-10-28 | Novel potentiating compounds |
Country Status (1)
| Country | Link |
|---|---|
| MY (1) | MY136047A (en) |
-
2003
- 2003-10-28 MY MYPI20034101 patent/MY136047A/en unknown
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