MY137536A - Glutamine-auxothrophic human cells capable of producing proteins and capable of growing in a glutamine-free medium - Google Patents
Glutamine-auxothrophic human cells capable of producing proteins and capable of growing in a glutamine-free mediumInfo
- Publication number
- MY137536A MY137536A MYPI20030143A MY137536A MY 137536 A MY137536 A MY 137536A MY PI20030143 A MYPI20030143 A MY PI20030143A MY 137536 A MY137536 A MY 137536A
- Authority
- MY
- Malaysia
- Prior art keywords
- glutamine
- growing
- free medium
- auxothrophic
- human cells
- Prior art date
Links
- 210000005260 human cell Anatomy 0.000 title abstract 2
- 102000004169 proteins and genes Human genes 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 title abstract 2
- 108091029865 Exogenous DNA Proteins 0.000 abstract 4
- 108020004414 DNA Proteins 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 102000005396 glutamine synthetase Human genes 0.000 abstract 1
- 108020002326 glutamine synthetase Proteins 0.000 abstract 1
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
A GLUTAMINE-AUXOTROPHIC HUMAN CELL TRANSFECTED WITH AN EXOGENOUS DNA SEQUENCE ENCODING A PROTAIN OR AN EXOGENOUS DNA SEQUENCE CAPABLE OF ALTERING THE EXPRESSION OF AN ENDOGENOUS GANE ENCODING A PROTEIN AND AN EXOGENOUS DNA SEQUENCE ENCODING A GLUTAMINE SYNTHETASE, WHEREIN THESE EXOGENOUS DNA SEQUENCES ARE LOCATED ON ONE OR MORE THAN ONE DNA CONSTRUCT, SAID TRANSFECTED CELL CAPABLE OF PRODUCING SAID PROTAIN AND CAPABLE OF GROWING IN A GLUTAMINE-FREE MEDIUM.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0200977A GB0200977D0 (en) | 2002-01-17 | 2002-01-17 | Glutamine-auxotrophic human cells capable of producing proteins and capable of growing in a glutamine-free medium |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY137536A true MY137536A (en) | 2009-02-27 |
Family
ID=9929201
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI20070692 MY136860A (en) | 2002-01-17 | 2003-01-16 | Glutamine-auxothrophic human cells capable of producing proteins and capable of growing in a glutamine-free medium |
| MYPI20030143 MY137536A (en) | 2002-01-17 | 2003-01-16 | Glutamine-auxothrophic human cells capable of producing proteins and capable of growing in a glutamine-free medium |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI20070692 MY136860A (en) | 2002-01-17 | 2003-01-16 | Glutamine-auxothrophic human cells capable of producing proteins and capable of growing in a glutamine-free medium |
Country Status (4)
| Country | Link |
|---|---|
| CN (2) | CN100497634C (en) |
| GB (1) | GB0200977D0 (en) |
| MY (2) | MY136860A (en) |
| TW (2) | TWI349038B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9279139B2 (en) * | 2011-06-21 | 2016-03-08 | University Of Guelph | Media comprising a glutamine biosensor and methods of use thereof |
| JP6972022B2 (en) * | 2016-05-11 | 2021-11-24 | アムジエン・インコーポレーテツド | Direct selection of high-level heteromer protein-expressing cells using an intragenic complementary vector of glutamine synthesizer |
| US20260226524A1 (en) * | 2023-01-29 | 2026-08-06 | Zencore Corporation | Glutamine synthetase marker for recombinant expression |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8601597D0 (en) * | 1986-01-23 | 1986-02-26 | Wilson R H | Nucleotide sequences |
| TW402639B (en) * | 1992-12-03 | 2000-08-21 | Transkaryotic Therapies Inc | Protein production and protein delivery |
| BR9811542A (en) * | 1997-07-23 | 2000-08-22 | Roche Diagnostics Gmbh | Identification of human cell lines for the production of human proteins through endogenous gene activation |
-
2002
- 2002-01-17 GB GB0200977A patent/GB0200977D0/en not_active Ceased
-
2003
- 2003-01-15 TW TW092100765A patent/TWI349038B/en not_active IP Right Cessation
- 2003-01-15 TW TW96115526A patent/TWI352120B/en not_active IP Right Cessation
- 2003-01-16 MY MYPI20070692 patent/MY136860A/en unknown
- 2003-01-16 MY MYPI20030143 patent/MY137536A/en unknown
- 2003-01-17 CN CNB2006101667253A patent/CN100497634C/en not_active Expired - Fee Related
- 2003-01-17 CN CN2009100029634A patent/CN101492656B/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| MY136860A (en) | 2008-11-28 |
| TWI349038B (en) | 2011-09-21 |
| TWI352120B (en) | 2011-11-11 |
| CN1966682A (en) | 2007-05-23 |
| GB0200977D0 (en) | 2002-03-06 |
| CN100497634C (en) | 2009-06-10 |
| CN101492656A (en) | 2009-07-29 |
| TW200734461A (en) | 2007-09-16 |
| CN101492656B (en) | 2011-05-04 |
| TW200307047A (en) | 2003-12-01 |
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