MY140251A - Bicyclic aryl-sulfonic acid [1,3,4]-thiadiazol-2-yl-amides, processes for their preparation and their use as pharmaceuticals - Google Patents
Bicyclic aryl-sulfonic acid [1,3,4]-thiadiazol-2-yl-amides, processes for their preparation and their use as pharmaceuticalsInfo
- Publication number
- MY140251A MY140251A MYPI20080798A MY140251A MY 140251 A MY140251 A MY 140251A MY PI20080798 A MYPI20080798 A MY PI20080798A MY 140251 A MY140251 A MY 140251A
- Authority
- MY
- Malaysia
- Prior art keywords
- disorders
- thiadiazol
- amides
- processes
- sulfonic acid
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 125000002619 bicyclic group Chemical group 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 3
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- 206010022489 Insulin Resistance Diseases 0.000 abstract 1
- 239000000556 agonist Substances 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000003210 demyelinating effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000004129 fatty acid metabolism Effects 0.000 abstract 1
- 239000008103 glucose Substances 0.000 abstract 1
- 208000015122 neurodegenerative disease Diseases 0.000 abstract 1
- 210000001428 peripheral nervous system Anatomy 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
- C07D285/125—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
- C07D285/135—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
THE INVENTION RELATES TO BICYCLIC ARYL-SULFONIC ACID [1,3,4] THIADIAZOL-2-YL-AMIDES OF THE FORMULA (1) AND TO THEIR PHYSIOLOGICALLY ACCEPTABLE SALTS AND PHYSIOLOGICALLY FUNCTIONAL DERIVATIVES SHOWING PPARDELTA, -ALPHA AND -GAMMA AGONIST ACTIVITY, IN WHICH THE RADICALS ARE AS DEFINED, AND THEIR PHYSIOLOGICALLY ACCEPTABLE SALTS AND PROCESSES FOR THEIR PREPARATIONS. THE COMPOUNDS ARE SUITABLE FOR THE TREATMENT AND/OR PREVENTION OF DISORDERS OF FATTY ACID METABOLISM AND GLUCOSE UTILIZATION DISORDERS AS WELL AS OF DISORDERS IN WHICH INSULIN RESISTANCE IS INVOLVED AND DEMYELINATING AND OTHER NEURODEGENERATIVE DISORDERS OF THE CENTRAL AND PERIPHERAL NERVOUS SYSTEM.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05021785 | 2005-10-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY140251A true MY140251A (en) | 2009-12-31 |
Family
ID=35459548
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI20080798 MY140251A (en) | 2005-10-06 | 2008-03-24 | Bicyclic aryl-sulfonic acid [1,3,4]-thiadiazol-2-yl-amides, processes for their preparation and their use as pharmaceuticals |
Country Status (2)
| Country | Link |
|---|---|
| MY (1) | MY140251A (en) |
| TW (1) | TW200730516A (en) |
-
2006
- 2006-09-27 TW TW095135656A patent/TW200730516A/en unknown
-
2008
- 2008-03-24 MY MYPI20080798 patent/MY140251A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TW200730516A (en) | 2007-08-16 |
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