MY140835A - Substituted 1-aminoalkyl-lactams and their use as muscarinic receptor antagonists - Google Patents

Substituted 1-aminoalkyl-lactams and their use as muscarinic receptor antagonists

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Publication number
MY140835A
MY140835A MYPI20012428A MYPI20012428A MY140835A MY 140835 A MY140835 A MY 140835A MY PI20012428 A MYPI20012428 A MY PI20012428A MY PI20012428 A MYPI20012428 A MY PI20012428A MY 140835 A MY140835 A MY 140835A
Authority
MY
Malaysia
Prior art keywords
receptor antagonists
lactams
aminoalkyl
substituted
muscarinic receptor
Prior art date
Application number
MYPI20012428A
Inventor
Charles Alois Dvorak
Lawrence Emerson Fisher
Keena Lynn Green
Ralph New Harris Iii
Hans Maag
Anthony Prince
David Bruce Repke
Russell Stephen Stabler
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MY140835A publication Critical patent/MY140835A/en

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Abstract

THIS INVENTION RELATES TO COMPOUNDS WHICH ARE GENERALLY MUSCARINIC M2/M3 RECEPTOR ANTAGONISTS AND WHICH ARE REPRESENTED BY FORMULAWHEREIN X, Y, AND Z ARE -0-, -8- OR >N-R5, AND THE OTHER SUBSTITUENTS ARE AS DEFINED IN THE SPECIFICATION; OR PRODRUGS, INDIVIDUAL ISOMERS, RACEMIC OR NON- RACEMIC MIXTURES OF ISOMERS, AND PHARMACEUTICALLY ACCEPTABLE SALTS OR SOLVATES THEREOF. THE INVENTION FURTHER RELATES TO PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THEIR USE FOR TREATING DISEASES ASSOCIATED WITH SMOOTH MUSCLE DISORDERS.
MYPI20012428A 2000-05-25 2001-05-23 Substituted 1-aminoalkyl-lactams and their use as muscarinic receptor antagonists MY140835A (en)

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