MY144322A - 8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions - Google Patents

8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions

Info

Publication number
MY144322A
MY144322A MYPI20050575A MYPI20050575A MY144322A MY 144322 A MY144322 A MY 144322A MY PI20050575 A MYPI20050575 A MY PI20050575A MY PI20050575 A MYPI20050575 A MY PI20050575A MY 144322 A MY144322 A MY 144322A
Authority
MY
Malaysia
Prior art keywords
xanthines
piperidin
amino
preparation
pharmaceutical compositions
Prior art date
Application number
MYPI20050575A
Inventor
Frank Himmelsbach
Elke Langkopf
Matthias Eckhardt
Mohammad Tadayyon
Leo Thomas
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34922894&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MY144322(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE102004008112A external-priority patent/DE102004008112A1/en
Priority claimed from DE102004012921A external-priority patent/DE102004012921A1/en
Priority claimed from DE102004032263A external-priority patent/DE102004032263A1/en
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of MY144322A publication Critical patent/MY144322A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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    • A61P9/12—Antihypertensives

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Reproductive Health (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Virology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Psychiatry (AREA)
  • Communicable Diseases (AREA)
  • Cardiology (AREA)
  • Psychology (AREA)
  • Emergency Medicine (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)

Abstract

THE PRESENT INVENTION RELATES TO SUBSTITUTED XANTHINES OF GENERAL FORMULA WHEREIN R IS DEFINED AS IN CLAIM 1, THE TAUTOMERS, THE STEREOISOMERS, THE MIXTURES THEREOF AND THE SALTS THEREOF, WHICH HAVE VALUABLE PHARMACOLOGICAL PROPERTIES, PARTICULARLY AN INHIBITING EFFECT ON THE ACTIVITY OF THE ENZYME DIPEPTIDYLPEPTIDASE-IV (DPP-IV ).
MYPI20050575A 2004-02-18 2005-02-16 8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions MY144322A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102004008112A DE102004008112A1 (en) 2004-02-18 2004-02-18 New 8-aminopiperidinyl-xanthine derivatives, useful for treating e.g. diabetes, arthritis and osteoporosis, are inhibitors of dipeptidylpeptidase-IV
DE102004012921A DE102004012921A1 (en) 2004-03-17 2004-03-17 New 7-butynyl-8-(3-amino-1-piperidinyl)xanthine derivatives useful as dipeptidyl peptidase IV inhibitors, e.g. for treating diabetes, arthritis, obesity and osteoporosis
DE102004032263A DE102004032263A1 (en) 2004-07-03 2004-07-03 New 7-butynyl-8-(3-amino-1-piperidinyl)xanthine derivatives useful as dipeptidyl peptidase IV inhibitors, e.g. for treating diabetes, arthritis, obesity and osteoporosis

Publications (1)

Publication Number Publication Date
MY144322A true MY144322A (en) 2011-08-29

Family

ID=34922894

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI20050575A MY144322A (en) 2004-02-18 2005-02-16 8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions

Country Status (29)

Country Link
EP (2) EP2119717B1 (en)
JP (2) JP4733058B2 (en)
KR (1) KR101207224B1 (en)
CN (1) CN102199151A (en)
AR (1) AR047614A1 (en)
AT (1) ATE430150T1 (en)
AU (1) AU2005219508B2 (en)
BR (1) BRPI0507873B8 (en)
CA (1) CA2555050C (en)
CY (1) CY1109284T1 (en)
DE (1) DE502005007196D1 (en)
DK (1) DK1758905T3 (en)
EA (2) EA010854B1 (en)
EC (1) ECSP066775A (en)
ES (1) ES2326666T3 (en)
HR (1) HRP20090346T1 (en)
IL (2) IL176920A (en)
ME (1) ME01108B (en)
MY (1) MY144322A (en)
NO (1) NO20062688L (en)
NZ (1) NZ548901A (en)
PE (1) PE20060210A1 (en)
PL (1) PL1758905T3 (en)
PT (1) PT1758905E (en)
RS (1) RS50982B (en)
SI (1) SI1758905T1 (en)
TW (1) TWI350756B (en)
UY (1) UY28749A1 (en)
WO (1) WO2005085246A1 (en)

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US7569574B2 (en) 2002-08-22 2009-08-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Purine derivatives, the preparation thereof and their use as pharmaceutical compositions
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US7393847B2 (en) 2004-03-13 2008-07-01 Boehringer Ingleheim International Gmbh Imidazopyridazinediones, their preparation and their use as pharmaceutical compositions
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