MY144578A - New polymorphous forms of rifaximin, processes for their production and use thereof in the medicinal preparations - Google Patents
New polymorphous forms of rifaximin, processes for their production and use thereof in the medicinal preparationsInfo
- Publication number
- MY144578A MY144578A MYPI20071229A MY144578A MY 144578 A MY144578 A MY 144578A MY PI20071229 A MYPI20071229 A MY PI20071229A MY 144578 A MY144578 A MY 144578A
- Authority
- MY
- Malaysia
- Prior art keywords
- rifaximin
- production
- medicinal preparations
- polymorphous forms
- processes
- Prior art date
Links
- NZCRJKRKKOLAOJ-XRCRFVBUSA-N rifaximin Chemical compound OC1=C(C(O)=C2C)C3=C4N=C5C=C(C)C=CN5C4=C1NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@H](C)[C@@H](OC)\C=C\O[C@@]1(C)OC2=C3C1=O NZCRJKRKKOLAOJ-XRCRFVBUSA-N 0.000 title abstract 7
- 229960003040 rifaximin Drugs 0.000 title abstract 6
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- 238000002425 crystallisation Methods 0.000 abstract 2
- 230000008025 crystallization Effects 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- 230000003115 biocidal effect Effects 0.000 abstract 1
- 239000007795 chemical reaction product Substances 0.000 abstract 1
- 238000001035 drying Methods 0.000 abstract 1
- 235000019441 ethanol Nutrition 0.000 abstract 1
- 239000000047 product Substances 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
CRYSTALLINE POLYMORPHOUS FORMS OF THE RIFAXIMIN (INN) ANTIBIOTIC NAMED RIFAXIMIN δ AND RIFAXIMIN ε USEFUL IN THE PRODUCTION OF MEDICINAL PREPARATIONS CONTAINING RIFAXIMIN FOR ORAL AND TOPICAL USE AND OBTAINED BY MEANS OF A CRYSTALLIZATION PROCESS CARRIED OUT BY HOT-DISSOLVING THE RAW RIFAXIMIN IN ETHYL ALCOHOL AND BY CAUSING THE CRYSTALLIZATION OF THE PRODUCT BY ADDITION OF WATER AT A DETERMINATE TEMPERATURE AND FOR A DETERMINATE PERIOD OF TIME, FOLLOWED BY A DRYING CARRIED OUT UNDER CONTROLLED CONDITIONS UNTIL REACHING A SETTLED WATER CONTENT IN THE END PRODUCT, ARE THE OBJECT OF THE INVENTION.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MYPI20071229 MY144578A (en) | 2007-07-27 | 2007-07-27 | New polymorphous forms of rifaximin, processes for their production and use thereof in the medicinal preparations |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MYPI20071229 MY144578A (en) | 2007-07-27 | 2007-07-27 | New polymorphous forms of rifaximin, processes for their production and use thereof in the medicinal preparations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY144578A true MY144578A (en) | 2011-10-14 |
Family
ID=45443242
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI20071229 MY144578A (en) | 2007-07-27 | 2007-07-27 | New polymorphous forms of rifaximin, processes for their production and use thereof in the medicinal preparations |
Country Status (1)
| Country | Link |
|---|---|
| MY (1) | MY144578A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2536734A4 (en) * | 2010-02-19 | 2013-06-26 | Salix Pharmaceuticals Ltd | Forms of rifaximin and uses thereof |
-
2007
- 2007-07-27 MY MYPI20071229 patent/MY144578A/en unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2536734A4 (en) * | 2010-02-19 | 2013-06-26 | Salix Pharmaceuticals Ltd | Forms of rifaximin and uses thereof |
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