MY145565A - Injectable preparations of diclofenic and its pharmaceutically acceptable salts - Google Patents
Injectable preparations of diclofenic and its pharmaceutically acceptable saltsInfo
- Publication number
- MY145565A MY145565A MYPI20070514A MY145565A MY 145565 A MY145565 A MY 145565A MY PI20070514 A MYPI20070514 A MY PI20070514A MY 145565 A MY145565 A MY 145565A
- Authority
- MY
- Malaysia
- Prior art keywords
- injectable preparations
- diclofenic
- pharmaceutically acceptable
- water
- diclofenac
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title abstract 3
- 150000003839 salts Chemical class 0.000 title abstract 2
- DCOPUUMXTXDBNB-UHFFFAOYSA-N diclofenac Chemical class OC(=O)CC1=CC=CC=C1NC1=C(Cl)C=CC=C1Cl DCOPUUMXTXDBNB-UHFFFAOYSA-N 0.000 abstract 3
- 238000002347 injection Methods 0.000 abstract 3
- 239000007924 injection Substances 0.000 abstract 3
- 229960001259 diclofenac Drugs 0.000 abstract 2
- 239000000243 solution Substances 0.000 abstract 2
- XLYOFNOQVPJJNP-PWCQTSIFSA-N Tritiated water Chemical compound [3H]O[3H] XLYOFNOQVPJJNP-PWCQTSIFSA-N 0.000 abstract 1
- 239000003963 antioxidant agent Substances 0.000 abstract 1
- 239000000872 buffer Substances 0.000 abstract 1
- 239000006184 cosolvent Substances 0.000 abstract 1
- 239000007972 injectable composition Substances 0.000 abstract 1
- 238000001990 intravenous administration Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000003755 preservative agent Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 239000003381 stabilizer Substances 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
INJECTABLE PREPARATIONS OF DICLOFENIC AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS 5 'ME PRESENT INVENTION PROVIDES INJECTABLE FORMULATIONS OF WATER-SOLUBLE SALTS OF DICLOFENAC IN SINGLE DOSES OF LESS THAN 2 ML, WHICH CAUSE SIGNIFICANTLY LESS PAIN AT THE SITE OF INJECTION AND CAN BE ADMINISTERED BY INTRADELTOID ROUTE, IN ADDITION TO INTRAGLUTEAL AND SLOW INTRAVENOUS ROUTE. MORE SPECIFICALLY THE INJECTABLE PREPARATIONS CONTAIN 75 MG TO 100 MG OF 1 0 WATER-SOLUBLE SALTS OF DICLOFENAC, IN ABOUT I ML INJECTION SOLUTION WITHOUT SIGNIFICANTLY RAISING THE VISCOSITY OF THE INJECTION SOLUTION WITHOUT THE USE SURFACTANTS. THE FORMULATIONS ARE ADJUSTED TO PH 6 TO 10 CONTAINING UP TO 100MG OF DICLOFENAC SALT IN A MEDIUM COMPRISING OF WATER, ALONG WITH ONE OR MORE CO-SOLVENT(S) / SOLUBILISER(S), ANTIOXIDANTS, PRESERVATIVES, BUFFERS, ALKALI AND STABILIZERS. 20M 0*QLO'@
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MYPI20070514 MY145565A (en) | 2007-04-02 | 2007-04-02 | Injectable preparations of diclofenic and its pharmaceutically acceptable salts |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MYPI20070514 MY145565A (en) | 2007-04-02 | 2007-04-02 | Injectable preparations of diclofenic and its pharmaceutically acceptable salts |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY145565A true MY145565A (en) | 2012-02-29 |
Family
ID=45891273
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI20070514 MY145565A (en) | 2007-04-02 | 2007-04-02 | Injectable preparations of diclofenic and its pharmaceutically acceptable salts |
Country Status (1)
| Country | Link |
|---|---|
| MY (1) | MY145565A (en) |
-
2007
- 2007-04-02 MY MYPI20070514 patent/MY145565A/en unknown
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