MY146643A - Novel benzoimidazole derivatives and pharmaceutical composition comprising the same - Google Patents
Novel benzoimidazole derivatives and pharmaceutical composition comprising the sameInfo
- Publication number
- MY146643A MY146643A MYPI20071245A MYPI20071245A MY146643A MY 146643 A MY146643 A MY 146643A MY PI20071245 A MYPI20071245 A MY PI20071245A MY PI20071245 A MYPI20071245 A MY PI20071245A MY 146643 A MY146643 A MY 146643A
- Authority
- MY
- Malaysia
- Prior art keywords
- pain
- pharmaceutical composition
- same
- benzoimidazole derivatives
- novel benzoimidazole
- Prior art date
Links
- HYZJCKYKOHLVJF-UHFFFAOYSA-N 1H-benzimidazole Chemical class C1=CC=C2NC=NC2=C1 HYZJCKYKOHLVJF-UHFFFAOYSA-N 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 208000002193 Pain Diseases 0.000 abstract 3
- 208000006820 Arthralgia Diseases 0.000 abstract 1
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 abstract 1
- 208000000094 Chronic Pain Diseases 0.000 abstract 1
- 208000032131 Diabetic Neuropathies Diseases 0.000 abstract 1
- 206010020751 Hypersensitivity Diseases 0.000 abstract 1
- 208000019695 Migraine disease Diseases 0.000 abstract 1
- 208000028389 Nerve injury Diseases 0.000 abstract 1
- 201000009053 Neurodermatitis Diseases 0.000 abstract 1
- 208000004550 Postoperative Pain Diseases 0.000 abstract 1
- 208000003251 Pruritus Diseases 0.000 abstract 1
- 201000004681 Psoriasis Diseases 0.000 abstract 1
- 102100029613 Transient receptor potential cation channel subfamily V member 1 Human genes 0.000 abstract 1
- 108050004388 Transient receptor potential cation channel subfamily V member 1 Proteins 0.000 abstract 1
- 206010047700 Vomiting Diseases 0.000 abstract 1
- 208000005298 acute pain Diseases 0.000 abstract 1
- 208000026935 allergic disease Diseases 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 208000000718 duodenal ulcer Diseases 0.000 abstract 1
- 230000009610 hypersensitivity Effects 0.000 abstract 1
- 208000027866 inflammatory disease Diseases 0.000 abstract 1
- 230000002757 inflammatory effect Effects 0.000 abstract 1
- 208000028774 intestinal disease Diseases 0.000 abstract 1
- 208000002551 irritable bowel syndrome Diseases 0.000 abstract 1
- 230000007794 irritation Effects 0.000 abstract 1
- 230000007803 itching Effects 0.000 abstract 1
- 210000004400 mucous membrane Anatomy 0.000 abstract 1
- 230000008764 nerve damage Effects 0.000 abstract 1
- 208000004296 neuralgia Diseases 0.000 abstract 1
- 230000000926 neurological effect Effects 0.000 abstract 1
- 208000021722 neuropathic pain Diseases 0.000 abstract 1
- 201000001119 neuropathy Diseases 0.000 abstract 1
- 230000007823 neuropathy Effects 0.000 abstract 1
- 208000033808 peripheral neuropathy Diseases 0.000 abstract 1
- 208000023504 respiratory system disease Diseases 0.000 abstract 1
- 230000008673 vomiting Effects 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
DISCLOSED HEREIN ARE NOVEL BENZOIMIDAZOLE DERIVATIVES FUNCTIONING AS ANTAGONISTS TO VANILLOID RECEPTOR-1, AND A PHARMACEUTICAL COMPOSITION COMPRISING THE SAME. THEY ARE USEFUL IN PREVENTING OR TREATING PAIN, ACUTE PAIN, CHRONIC PAIN, NEUROPATHIC PAIN, POSTOPERATIVE PAIN, MIGRAINES, ARTHRALGIA, NEUROPATHY, NERVE INJURY, DIABETIC NEUROPATHY, NEUROLOGICAL ILLNESS, NEURODERMATITIS, STROKES, BLADDER HYPERSENSITIVITY, IRRITABLE BOWEL SYNDROME, RESPIRATORY DISORDERS SUCH AS ASTHMA, CHRONIC OBSTRUCTIVE PULMONARY DISEASE, ETC., BURNS, PSORIASIS, ITCHING, VOMITING, IRRITATION OF THE SKIN, EYES, AND MUCOUS MEMBRANES, GASTRIC-DUODENAL ULCERS, INFLAMMATORY INTESTINAL DISEASES, AND INFLAMMATORY DISEASES.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MYPI20071245A MY146643A (en) | 2007-07-30 | 2007-07-30 | Novel benzoimidazole derivatives and pharmaceutical composition comprising the same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MYPI20071245A MY146643A (en) | 2007-07-30 | 2007-07-30 | Novel benzoimidazole derivatives and pharmaceutical composition comprising the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY146643A true MY146643A (en) | 2012-09-14 |
Family
ID=48041011
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI20071245A MY146643A (en) | 2007-07-30 | 2007-07-30 | Novel benzoimidazole derivatives and pharmaceutical composition comprising the same |
Country Status (1)
| Country | Link |
|---|---|
| MY (1) | MY146643A (en) |
Cited By (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10028950B2 (en) | 2014-10-24 | 2018-07-24 | Landos Biopharma, Inc. | Lanthionine synthetase C-like 2-based therapeutics |
| US10722495B2 (en) | 2017-09-08 | 2020-07-28 | Incyte Corporation | Cyanoindazole compounds and uses thereof |
| US10745388B2 (en) | 2018-02-20 | 2020-08-18 | Incyte Corporation | Indazole compounds and uses thereof |
| US10752635B2 (en) | 2018-02-20 | 2020-08-25 | Incyte Corporation | Indazole compounds and uses thereof |
| US10800761B2 (en) | 2018-02-20 | 2020-10-13 | Incyte Corporation | Carboxamide compounds and uses thereof |
| US10899755B2 (en) | 2018-08-08 | 2021-01-26 | Incyte Corporation | Benzothiazole compounds and uses thereof |
| US10934288B2 (en) | 2016-09-09 | 2021-03-02 | Incyte Corporation | Pyrazolopyridine compounds and uses thereof |
| US11014929B2 (en) | 2016-09-09 | 2021-05-25 | Incyte Corporation | Pyrazolopyrimidine compounds and uses thereof |
| US11066394B2 (en) | 2019-08-06 | 2021-07-20 | Incyte Corporation | Solid forms of an HPK1 inhibitor |
| US11111247B2 (en) | 2018-09-25 | 2021-09-07 | Incyte Corporation | Pyrazolopyrimidine compounds and uses thereof |
| US11117881B2 (en) | 2019-12-20 | 2021-09-14 | Landos Biopharma, Inc. | Lanthionine c-like protein 2 ligands, cells prepared therewith, and therapies using same |
| US11197891B2 (en) | 2017-11-30 | 2021-12-14 | Landos Biopharma, Inc. | Therapies with lanthionine C-like protein 2 ligands and cells prepared therewith |
| US11242343B2 (en) | 2016-09-09 | 2022-02-08 | Incyte Corporation | Pyrazolopyridine compounds and uses thereof |
| US11299473B2 (en) | 2018-04-13 | 2022-04-12 | Incyte Corporation | Benzimidazole and indole compounds and uses thereof |
| US11406624B2 (en) | 2017-02-15 | 2022-08-09 | Incyte Corporation | Pyrazolopyridine compounds and uses thereof |
-
2007
- 2007-07-30 MY MYPI20071245A patent/MY146643A/en unknown
Cited By (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10849895B2 (en) | 2014-10-24 | 2020-12-01 | Landos Biopharma, Inc. | Lanthionine synthetase C-like 2-based therapeutics |
| US10201538B2 (en) | 2014-10-24 | 2019-02-12 | Landos Biopharma, Inc. | Lanthionine synthetase C-like 2-based therapeutics |
| US10493072B2 (en) | 2014-10-24 | 2019-12-03 | Landos Biopharma, Inc. | Lanthionine synthetase C-like 2-based therapeutics |
| US10682349B2 (en) | 2014-10-24 | 2020-06-16 | Landos Biopharma, Inc. | Lanthionine synthetase C-like 2-based therapeutics |
| US12502388B2 (en) | 2014-10-24 | 2025-12-23 | Nimmune Biopharma, Inc. | Lanthionine synthetase C-like 2-based therapeutics |
| US11571419B2 (en) | 2014-10-24 | 2023-02-07 | Landos Biopharma, Inc. | Lanthionine synthetase C-like 2-based therapeutics |
| US10028950B2 (en) | 2014-10-24 | 2018-07-24 | Landos Biopharma, Inc. | Lanthionine synthetase C-like 2-based therapeutics |
| US11242343B2 (en) | 2016-09-09 | 2022-02-08 | Incyte Corporation | Pyrazolopyridine compounds and uses thereof |
| US11891388B2 (en) | 2016-09-09 | 2024-02-06 | Incyte Corporation | Pyrazolopyridine compounds and uses thereof |
| US12516059B2 (en) | 2016-09-09 | 2026-01-06 | Incyte Corporation | Pyrazolopyridine compounds and uses thereof |
| US10934288B2 (en) | 2016-09-09 | 2021-03-02 | Incyte Corporation | Pyrazolopyridine compounds and uses thereof |
| US11014929B2 (en) | 2016-09-09 | 2021-05-25 | Incyte Corporation | Pyrazolopyrimidine compounds and uses thereof |
| US11542265B2 (en) | 2016-09-09 | 2023-01-03 | Incyte Corporation | Pyrazolopyrimidine compounds and uses thereof |
| US12384778B2 (en) | 2016-09-09 | 2025-08-12 | Incyte Corporation | Pyrazolopyridine compounds and uses thereof |
| US11795166B2 (en) | 2016-09-09 | 2023-10-24 | Incyte Corporation | Pyrazolopyridine compounds and uses thereof |
| US11406624B2 (en) | 2017-02-15 | 2022-08-09 | Incyte Corporation | Pyrazolopyridine compounds and uses thereof |
| US10722495B2 (en) | 2017-09-08 | 2020-07-28 | Incyte Corporation | Cyanoindazole compounds and uses thereof |
| US11197891B2 (en) | 2017-11-30 | 2021-12-14 | Landos Biopharma, Inc. | Therapies with lanthionine C-like protein 2 ligands and cells prepared therewith |
| US10752635B2 (en) | 2018-02-20 | 2020-08-25 | Incyte Corporation | Indazole compounds and uses thereof |
| US11492354B2 (en) | 2018-02-20 | 2022-11-08 | Incyte Corporation | Indazole compounds and uses thereof |
| US12466815B2 (en) | 2018-02-20 | 2025-11-11 | Incyte Corporation | Carboxamide compounds and uses thereof |
| US10745388B2 (en) | 2018-02-20 | 2020-08-18 | Incyte Corporation | Indazole compounds and uses thereof |
| US11731958B2 (en) | 2018-02-20 | 2023-08-22 | Incyte Corporation | Carboxamide compounds and uses thereof |
| US10800761B2 (en) | 2018-02-20 | 2020-10-13 | Incyte Corporation | Carboxamide compounds and uses thereof |
| US11299473B2 (en) | 2018-04-13 | 2022-04-12 | Incyte Corporation | Benzimidazole and indole compounds and uses thereof |
| US11866426B2 (en) | 2018-08-08 | 2024-01-09 | Incyte Corporation | Benzothiazole compounds and uses thereof |
| US10899755B2 (en) | 2018-08-08 | 2021-01-26 | Incyte Corporation | Benzothiazole compounds and uses thereof |
| US12441731B2 (en) | 2018-09-25 | 2025-10-14 | Incyte Corporation | Pyrazolopyrimidine compounds and uses thereof |
| US11111247B2 (en) | 2018-09-25 | 2021-09-07 | Incyte Corporation | Pyrazolopyrimidine compounds and uses thereof |
| US11787784B2 (en) | 2019-08-06 | 2023-10-17 | Incyte Corporation | Solid forms of an HPK1 inhibitor |
| US11066394B2 (en) | 2019-08-06 | 2021-07-20 | Incyte Corporation | Solid forms of an HPK1 inhibitor |
| US11377437B2 (en) | 2019-12-20 | 2022-07-05 | Landos Biopharma, Inc. | Lanthionine C-like protein 2 ligands, cells prepared therewith, and therapies using same |
| US11117881B2 (en) | 2019-12-20 | 2021-09-14 | Landos Biopharma, Inc. | Lanthionine c-like protein 2 ligands, cells prepared therewith, and therapies using same |
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