MY148277A - Treatment of cartilage disorders with fgf-18 - Google Patents
Treatment of cartilage disorders with fgf-18Info
- Publication number
- MY148277A MY148277A MYPI20090702A MYPI20090702A MY148277A MY 148277 A MY148277 A MY 148277A MY PI20090702 A MYPI20090702 A MY PI20090702A MY PI20090702 A MYPI20090702 A MY PI20090702A MY 148277 A MY148277 A MY 148277A
- Authority
- MY
- Malaysia
- Prior art keywords
- treatment
- fgf
- osteoarthritis
- cartilage disorders
- cartilage disorder
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1825—Fibroblast growth factor [FGF]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
THIS INVENTION CONCERNS THE TREATMENT OF CARTILAGE DISORDER AND OSTEOARTHRITIS IN PARTICULAR. MORE SPECIFICALLY, IT RELATES TO THE USE OF FGF-18 IN TREATMENT REGIMENS AND FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF PATIENTS HAVING A CARTILAGE DISORDER SUCH AS OSTEOARTHRITIS, SUCH AS FOR EXAMPLE KNEE OSTEOARTHRITIS OR SECONDARY HIP OSTEOARTHRITIS. SPECIFICALLY PROVIDED IS A PREFERRED TREATMENT SCHEME COMPRISING ONCE WEEKLY ADMINISTRATION OF AN FGF-18 COMPOUND PER TREATMENT CYCLE.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06119557 | 2006-08-25 | ||
| US84060006P | 2006-08-28 | 2006-08-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY148277A true MY148277A (en) | 2013-03-29 |
Family
ID=37684849
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI20090702A MY148277A (en) | 2006-08-25 | 2007-08-24 | Treatment of cartilage disorders with fgf-18 |
Country Status (11)
| Country | Link |
|---|---|
| CN (1) | CN101505787B (en) |
| BR (1) | BRPI0715728A8 (en) |
| DK (1) | DK2054050T3 (en) |
| ES (1) | ES2392883T3 (en) |
| MY (1) | MY148277A (en) |
| NZ (1) | NZ574216A (en) |
| PT (1) | PT2054050E (en) |
| RS (1) | RS52710B (en) |
| SI (1) | SI2054050T1 (en) |
| UA (1) | UA99818C2 (en) |
| ZA (1) | ZA200900426B (en) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2880179B1 (en) * | 2012-08-06 | 2017-12-13 | Merck Patent GmbH | Genetic markers for predicting responsiveness to fgf-18 compound |
| HRP20181570T1 (en) * | 2014-02-20 | 2018-11-30 | Merck Patent Gmbh | DOSAGE MODE OF FGF-18 COMPOUND |
| KR102437057B1 (en) * | 2014-02-20 | 2022-08-26 | 메르크 파텐트 게엠베하 | Fgf-18 in graft transplantation and tissue engineering procedures |
| ES2698117T3 (en) * | 2014-02-20 | 2019-01-31 | Merck Patent Gmbh | Implant comprising FGF-18 |
| EP3250223A1 (en) * | 2015-01-08 | 2017-12-06 | University of Iowa Research Foundation | Methods for the regeneration of articular cartilage in vivo |
| US11020454B2 (en) | 2015-07-15 | 2021-06-01 | Prosit Sole Biotechnology (Beijing) Co. Ltd | Fusion polypeptides and methods of use |
| CA2994638A1 (en) * | 2015-08-13 | 2017-02-16 | Merck Patent Gmbh | Combination composition comprising fgf-18 compound |
| WO2020263989A1 (en) | 2019-06-24 | 2020-12-30 | University Of Iowa Research Foundation | Jnk inhibitors as anticancer agents |
| EP4061836A4 (en) * | 2019-11-21 | 2024-02-14 | Remedium Bio, Inc. | Growth factor restoration |
| US11904006B2 (en) | 2019-12-11 | 2024-02-20 | University Of Iowa Research Foundation | Poly(diaminosulfide) particle-based vaccine |
| CN117721115A (en) * | 2022-09-06 | 2024-03-19 | 深圳瑞吉生物科技有限公司 | mRNA for treating osteoarthritis and its preparation methods and applications |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1551426B1 (en) * | 2002-10-07 | 2014-06-25 | ZymoGenetics, Inc. | Methods of administering fgf18 |
| WO2006014444A1 (en) * | 2004-07-06 | 2006-02-09 | Zymogenetics, Inc. | Pharmaceutical composition comprising fgf18 and il-1 antagonist and method of use |
| DK1828239T3 (en) * | 2004-12-10 | 2011-12-19 | Zymogenetics Inc | FGF18 production in prokaryotic hosts |
-
2007
- 2007-08-24 NZ NZ574216A patent/NZ574216A/en unknown
- 2007-08-24 CN CN2007800312016A patent/CN101505787B/en active Active
- 2007-08-24 BR BRPI0715728A patent/BRPI0715728A8/en not_active Application Discontinuation
- 2007-08-24 SI SI200731047T patent/SI2054050T1/en unknown
- 2007-08-24 ES ES07802876T patent/ES2392883T3/en active Active
- 2007-08-24 ZA ZA200900426A patent/ZA200900426B/en unknown
- 2007-08-24 RS RS20120483A patent/RS52710B/en unknown
- 2007-08-24 DK DK07802876.8T patent/DK2054050T3/en active
- 2007-08-24 MY MYPI20090702A patent/MY148277A/en unknown
- 2007-08-24 PT PT07802876T patent/PT2054050E/en unknown
- 2007-08-24 UA UAA200902217A patent/UA99818C2/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN101505787B (en) | 2013-09-04 |
| BRPI0715728A2 (en) | 2013-09-17 |
| ES2392883T3 (en) | 2012-12-14 |
| ZA200900426B (en) | 2010-04-28 |
| PT2054050E (en) | 2012-09-17 |
| CN101505787A (en) | 2009-08-12 |
| RS52710B (en) | 2013-08-30 |
| SI2054050T1 (en) | 2012-12-31 |
| BRPI0715728A8 (en) | 2018-04-03 |
| UA99818C2 (en) | 2012-10-10 |
| DK2054050T3 (en) | 2012-09-03 |
| NZ574216A (en) | 2011-11-25 |
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