MY148804A - Heteroarylcarbamoylbenzene derivatives - Google Patents
Heteroarylcarbamoylbenzene derivativesInfo
- Publication number
- MY148804A MY148804A MYPI20043469A MY148804A MY 148804 A MY148804 A MY 148804A MY PI20043469 A MYPI20043469 A MY PI20043469A MY 148804 A MY148804 A MY 148804A
- Authority
- MY
- Malaysia
- Prior art keywords
- formula
- ring
- halogen
- optionally substituted
- nitrogen atom
- Prior art date
Links
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen(.) Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- 239000001301 oxygen Substances 0.000 abstract 2
- 102000030595 Glucokinase Human genes 0.000 abstract 1
- 108010021582 Glucokinase Proteins 0.000 abstract 1
- 230000003213 activating effect Effects 0.000 abstract 1
- 150000001408 amides Chemical group 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 150000001721 carbon Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
COMPOUNDS HAVING GLUCOKINASE ACTIVATING EFFECTS AND BEING USEFUL AS TREATMENTS FOR DIABETES, WHICH ARE REPRESENTED BY THE FOLLOWING FORMULA (I): [WHEREIN X� REPRESENTS OXYGEN, ETC., X� REPRESENTS OXYGEN, ETC., R� REPRESENTS A GROUP ON RING A SUCH AS ALKYLSULFONYL, ETC., R� REPRESENTS C3-7 CYCLIC ALKYL OPTIONALLY SUBSTITUTED WITH A HALOGEN, ETC., R� REPRESENTS C3-7 CYCLIC ALKYL OPTIONALLY SUBSTITUTED WITH A HALOGEN, ETC., R� REPRESENTS A SUBSTITUENT ON RING B SUCH AS LOWER ALKYL, ETC., FORMULA (II): [CHEMICAL FORMULA 1] REPRESENTS 6- TO 10-MEMBERED ARYL, ETC., AND FORMULA (III):[FORMULA 1] REPRESENTS MONOCYCLIC OR BICYCLIC HETEROARYL OPTIONALLY HAVING ON RING B A SUBSTITUENT REPRESENTED BY R� ABOVE, WHEREIN THE CARBON ATOM OF RING B WHICH IS BONDED TO THE NITROGEN ATOM OF THE AMIDE GROUP OF FORMULA (I) FORMS A C=N BOND WITH THE NITROGEN ATOM OF THE RING, AS WELL AS THEIR PHARMACEUTICALLY ACCEPTABLE SALTS.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003400882 | 2003-11-28 | ||
| JP2004031298 | 2004-02-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY148804A true MY148804A (en) | 2013-05-31 |
Family
ID=42778429
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI20043469 MY148804A (en) | 2003-11-28 | 2004-08-25 | Heteroarylcarbamoylbenzene derivatives |
Country Status (4)
| Country | Link |
|---|---|
| AR (1) | AR045578A1 (en) |
| MY (1) | MY148804A (en) |
| PE (1) | PE20050572A1 (en) |
| TW (1) | TWI341309B (en) |
-
2004
- 2004-08-06 TW TW093123730A patent/TWI341309B/en not_active IP Right Cessation
- 2004-08-25 MY MYPI20043469 patent/MY148804A/en unknown
- 2004-09-03 AR ARP040103170 patent/AR045578A1/en not_active Application Discontinuation
- 2004-09-03 PE PE2004000853A patent/PE20050572A1/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| TWI341309B (en) | 2011-05-01 |
| PE20050572A1 (en) | 2005-08-27 |
| TW200517385A (en) | 2005-06-01 |
| AR045578A1 (en) | 2005-11-02 |
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