MY155271A - Selective thrombin inhibitors - Google Patents

Selective thrombin inhibitors

Info

Publication number
MY155271A
MY155271A MYPI20014397A MYPI0104397A MY155271A MY 155271 A MY155271 A MY 155271A MY PI20014397 A MYPI20014397 A MY PI20014397A MY PI0104397 A MYPI0104397 A MY PI0104397A MY 155271 A MY155271 A MY 155271A
Authority
MY
Malaysia
Prior art keywords
substituted
lower alkyl
alkoxycarbonyl
unsubstituted
carboxyl
Prior art date
Application number
MYPI20014397A
Inventor
Yeong Soo Oh
You Seung Shin
Sang Soo Kim
Sang Yeul Hwang
Mi Kyung Yun
Seong Ryul Hwang
Seong Won Hong
Yong Hee Lee
Yi Na Jeong
Koo Lee
Original Assignee
Lg Chemical Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lg Chemical Ltd filed Critical Lg Chemical Ltd
Priority to MYPI20014397A priority Critical patent/MY155271A/en
Publication of MY155271A publication Critical patent/MY155271A/en

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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

THE PRESENT INVENTION RELATES TO A NOVEL SELECTIVE THROMBIN INHIBITOR HAVING THE FOLLOWING FORMULA (I), WHICH IS ALSO EFFECTIVE BY ORAL ADMINISTRATION: IN WHICH R1 REPRESENTS ACETYL SUBSTITUTED WITH ARYL OR ARYLOXY, OR REPRESENTS SULFONYL SUBSTITUTED WITH SUBSTITUTED OR UNSUBSTITUTED ARYL OR N-CONTAINING HETEROCYCLIC GROUP,X REPRESENTS A GROUP OF FORMULA -NOR -N N-R5 R2 AND R3 INDEPENDENTLY OF ONE ANOTHER REPRESENT HYDROGEN; CYCLOALKYL SUBSTITUTED OR UNSUBSTITUTED WITH CARBOXYL OR ALKOXYCARBONYL; ARYLALKYLOXY; HYDROXY; OR LOWER ALKYL SUBSTITUTED OR UNSUBSTITUTED WITH CARBOXYL, ALKOXYCARBONYL OR HYDROXY, OR R2 AND R3 TOGETHER WITH NITROGEN ATOM TO WHICH THEY ARE ATTACHED CAN FORM A PIPERIDINE GROUP SUBSTITUTED WITH CARBOXYL OR ALKOXYCARBONYL, R4 REPRESENTS HYDROGEN, LOWER ALKYL OR LOWER ALKOXY, R5 REPRESENTS ALKANESULFONYL; ALKOXYCARBONYL; ALKYLCARBONYL; FORMYL; LOWER ALKYL; ARYL SUBSTITUTED OR UNSUBSTITUTED WITH ALKOXY OR HALOALKYL; OR HYDROXY-SUBSTITUTED LOWER ALKYL, AND R6 AND R7 INDEPENDENTLY OF ONE ANOTHER REPRESENT HYDROGEN, LOWER ALKYL OR AMINO, AND TO A PROCESS FOR PREPARATION THEREOF AND A PHARMACEUTICAL COMPOSITION FOR THROMBIN INHIBITION WHICH COMPRISES THE COMPOUND OF FORMULA (I) AS AN ACTIVE INGREDIENT.
MYPI20014397A 1996-10-28 1996-10-28 Selective thrombin inhibitors MY155271A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
MYPI20014397A MY155271A (en) 1996-10-28 1996-10-28 Selective thrombin inhibitors

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MYPI20014397A MY155271A (en) 1996-10-28 1996-10-28 Selective thrombin inhibitors

Publications (1)

Publication Number Publication Date
MY155271A true MY155271A (en) 2015-09-30

Family

ID=54779985

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI20014397A MY155271A (en) 1996-10-28 1996-10-28 Selective thrombin inhibitors

Country Status (1)

Country Link
MY (1) MY155271A (en)

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