MY157582A - Medical composition containing rebamipipe - Google Patents
Medical composition containing rebamipipeInfo
- Publication number
- MY157582A MY157582A MYPI2010000374A MYPI20100374A MY157582A MY 157582 A MY157582 A MY 157582A MY PI2010000374 A MYPI2010000374 A MY PI2010000374A MY PI20100374 A MYPI20100374 A MY PI20100374A MY 157582 A MY157582 A MY 157582A
- Authority
- MY
- Malaysia
- Prior art keywords
- medical composition
- salt
- rebamipipe
- composition containing
- present
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 150000003839 salts Chemical class 0.000 abstract 5
- ALLWOAVDORUJLA-UHFFFAOYSA-N Rebamipida Chemical compound C=1C(=O)NC2=CC=CC=C2C=1CC(C(=O)O)NC(=O)C1=CC=C(Cl)C=C1 ALLWOAVDORUJLA-UHFFFAOYSA-N 0.000 abstract 3
- 229950004535 rebamipide Drugs 0.000 abstract 3
- ODKSFYDXXFIFQN-BYPYZUCNSA-N L-arginine Chemical compound OC(=O)[C@@H](N)CCCN=C(N)N ODKSFYDXXFIFQN-BYPYZUCNSA-N 0.000 abstract 2
- 235000019658 bitter taste Nutrition 0.000 abstract 2
- 235000003599 food sweetener Nutrition 0.000 abstract 2
- 239000003765 sweetening agent Substances 0.000 abstract 2
- 241000544066 Stevia Species 0.000 abstract 1
- IVPOQXWRUMMORK-UHFFFAOYSA-N Thaumatin b, recombinant Chemical compound C1=CC(NC(=O)C)=CC=C1S(=O)(=O)N1CCN(C2CCCCCC2)CC1 IVPOQXWRUMMORK-UHFFFAOYSA-N 0.000 abstract 1
- 229940068517 fruit extracts Drugs 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- HELXLJCILKEWJH-NCGAPWICSA-N rebaudioside A Chemical compound O([C@H]1[C@H](O)[C@@H](CO)O[C@H]([C@@H]1O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O HELXLJCILKEWJH-NCGAPWICSA-N 0.000 abstract 1
- 235000010436 thaumatin Nutrition 0.000 abstract 1
- 239000000892 thaumatin Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5015—Organic compounds, e.g. fats, sugars
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4704—2-Quinolinones, e.g. carbostyril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
THE PRESENT INVENTION PROVIDES A PHARMACEUTICAL PREPARATION WHEREIN THE EXPRESSION OF BITTERNESS IS REDUCED. THE MEDICAL COMPOSITION OF THE PRESENT INVENTION CONTAINS REBAMIPIDE OR A SALT THEREOF AND L-ARGININE OR A SALT THEREOF. THE PREFERABLE EMBODIMENT OF THE MEDICAL COMPOSITION OF THE PRESENT INVENTION CONTAINS REBAMIPIDE OR A SALT THEREOF AND L-ARGININE OR A SALT THEREOF ALONG WITH AT LEAST ONE SWEETENER SELECTED FROM THE GROUP CONSISTING OF THAUMATIN, STEVIA AND LUOHAN FRUIT EXTRACTS. BY ADDING SUCH A SWEETENER, BITTERNESS OF MEDICAL COMPOSITION ATTRIBUTABLE TO REBAMIPIDE OR A SALT THEREOF CAN BE REMARKABLY REDUCED.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2007209284 | 2007-08-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY157582A true MY157582A (en) | 2016-06-30 |
Family
ID=39884986
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI2010000374A MY157582A (en) | 2007-08-10 | 2008-08-05 | Medical composition containing rebamipipe |
Country Status (7)
| Country | Link |
|---|---|
| JP (2) | JP5328789B2 (en) |
| KR (1) | KR101551506B1 (en) |
| CN (1) | CN101778626B (en) |
| AR (1) | AR067887A1 (en) |
| MY (1) | MY157582A (en) |
| TW (1) | TW200918060A (en) |
| WO (1) | WO2009022674A1 (en) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA114600C2 (en) * | 2011-03-24 | 2017-07-10 | Оцука Фармасьютікал Ко., Лтд. | PHARMACEUTICAL COMPOSITION FOR TREATMENT OF DISEASES IN THE ORAL COVER |
| JP5756727B2 (en) * | 2011-09-30 | 2015-07-29 | ハウス食品グループ本社株式会社 | Granule |
| CN104768551B (en) * | 2012-07-31 | 2018-04-13 | 天主教大学产学协力团 | Composition for preventing or treating hyperlipidemia and related diseases containing rebamipide as an active ingredient |
| MY172574A (en) * | 2012-12-28 | 2019-12-03 | Kao Corp | Dicaffeoylquinic acid-containing drink |
| JP6468919B2 (en) * | 2014-03-31 | 2019-02-13 | 富士フイルム富山化学株式会社 | Granular solid formulation containing cephalosporin ester |
| KR20170039347A (en) * | 2015-10-01 | 2017-04-11 | 삼진제약주식회사 | Novel opthalmic composition comprising rebamipide and method for preparing the same |
| US20170295834A1 (en) * | 2015-11-25 | 2017-10-19 | Alexander LaCroix | All-Natural Bitterness-Reducing Flavor System |
| JP7057286B2 (en) | 2016-12-28 | 2022-04-19 | 富士フイルム富山化学株式会社 | Pharmaceutical composition |
| JP7011300B2 (en) * | 2017-12-19 | 2022-02-10 | 株式会社島田製薬 | HMBCa-containing granule manufacturing method and supplements |
| KR101923519B1 (en) * | 2018-06-26 | 2019-02-27 | 대우제약 주식회사 | A water-soluble, multi-use eyedrops composition for the treatment of dry eye syndrome containing rebamipide and a method for solubilization and stabilization thereof |
| JP7698962B2 (en) * | 2021-03-19 | 2025-06-26 | 三栄源エフ・エフ・アイ株式会社 | Methods for masking unpleasant flavors |
| KR20230090184A (en) | 2021-12-14 | 2023-06-21 | 메디케어제약 주식회사 | Pharmaceutical composite formulation comprising esomeprazole and rebamipide |
| KR20230090185A (en) | 2021-12-14 | 2023-06-21 | 메디케어제약 주식회사 | Pharmaceutical composite formulation for treating rheumatoid arthritis with gastric mucosal lesion |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0674515T3 (en) * | 1993-10-21 | 1999-12-20 | Otsuka Pharma Co Ltd | Use of Carbostyril Derivatives for the Preparation of a Drug for Inhibition of Interleukin-8 |
| JPH10306038A (en) * | 1997-05-07 | 1998-11-17 | Taisho Pharmaceut Co Ltd | Bromhexine-containing solution |
| JP3466921B2 (en) * | 1998-06-03 | 2003-11-17 | 大塚製薬株式会社 | Taste masking pharmaceutical formulation |
| JP3417857B2 (en) * | 1998-12-11 | 2003-06-16 | 日清オイリオ株式会社 | seasoning |
| KR20040104020A (en) * | 2003-06-02 | 2004-12-10 | 진양제약주식회사 | A new rebamipide lysinate, rebamipide argininate and pharmaceutical preparation containing the same as active substance |
| JP4244715B2 (en) * | 2003-06-12 | 2009-03-25 | 株式会社ノエビア | Condiment drink |
| TWI340650B (en) * | 2004-01-21 | 2011-04-21 | Otsuka Pharma Co Ltd | Amine saly of carbostyril derivative |
| JP2005312305A (en) * | 2004-04-27 | 2005-11-10 | Goodoo Kasei Kk | Health agent |
| JP4713104B2 (en) * | 2004-08-04 | 2011-06-29 | ファイザー株式会社 | A stable composition containing azithromycins as an active ingredient and having reduced bitterness |
| JP5680815B2 (en) * | 2005-04-22 | 2015-03-04 | 焼津水産化学工業株式会社 | Method for producing potassium chloride-containing food and drink, and potassium chloride-containing food and drink obtained by the production method |
| JP4881268B2 (en) * | 2006-09-25 | 2012-02-22 | あすか製薬株式会社 | Oral preparations with reduced bitterness |
-
2008
- 2008-08-05 WO PCT/JP2008/064385 patent/WO2009022674A1/en not_active Ceased
- 2008-08-05 CN CN200880102776.7A patent/CN101778626B/en not_active Expired - Fee Related
- 2008-08-05 MY MYPI2010000374A patent/MY157582A/en unknown
- 2008-08-05 KR KR1020107005185A patent/KR101551506B1/en not_active Expired - Fee Related
- 2008-08-05 JP JP2010519618A patent/JP5328789B2/en not_active Expired - Fee Related
- 2008-08-08 AR ARP080103471A patent/AR067887A1/en unknown
- 2008-08-08 TW TW097130221A patent/TW200918060A/en unknown
-
2013
- 2013-05-17 JP JP2013105172A patent/JP2013177418A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AR067887A1 (en) | 2009-10-28 |
| JP5328789B2 (en) | 2013-10-30 |
| CN101778626B (en) | 2014-05-07 |
| JP2013177418A (en) | 2013-09-09 |
| KR101551506B1 (en) | 2015-09-08 |
| WO2009022674A1 (en) | 2009-02-19 |
| JP2010535757A (en) | 2010-11-25 |
| KR20100051850A (en) | 2010-05-18 |
| CN101778626A (en) | 2010-07-14 |
| TW200918060A (en) | 2009-05-01 |
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