MY164890A - Stable and soluble antibodies inhibiting tnfa - Google Patents
Stable and soluble antibodies inhibiting tnfaInfo
- Publication number
- MY164890A MY164890A MYPI20072131A MYPI20072131A MY164890A MY 164890 A MY164890 A MY 164890A MY PI20072131 A MYPI20072131 A MY PI20072131A MY PI20072131 A MYPI20072131 A MY PI20072131A MY 164890 A MY164890 A MY 164890A
- Authority
- MY
- Malaysia
- Prior art keywords
- antibodies
- tnf
- stable
- soluble antibodies
- antibodies inhibiting
- Prior art date
Links
- 101150033527 TNF gene Proteins 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
- 102000001706 Immunoglobulin Fab Fragments Human genes 0.000 abstract 1
- 108010054477 Immunoglobulin Fab Fragments Proteins 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 230000005847 immunogenicity Effects 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Abstract
THE PRESENT INVENTION RELATES TO PARTICULARLY STABLE AND SOLUBLE SCFV ANTIBODIES AND FAB FRAGMENTS SPECIFIC FOR TNF?, WHICH COMPRISE SPECIFIC LIGHT CHAIN AND HEAVY CHAIN SEQUENCES THAT ARE OPTIMIZED FOR STABILITY, SOLUBILITY, IN VITRO AND IN VIVO BINDING OF TNF?, AND LOW IMMUNOGENICITY. SAID ANTIBODIES ARE DESIGNED FOR THE DIAGNOSIS AND/OR TREATMENT OF TNF?, RELATED DISORDERS. THE NUCLEIC ACIDS, VECTORS AND HOST CELLS FOR EXPRESSION OF THE RECOMBINANT ANTIBODIES OF THE INVENTION, METHODS FOR ISOLATING THEM AND THE USE OF SAID ANTIBODIES IN MEDICINE ARE ALSO DISCLOSED.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MYPI20072131A MY164890A (en) | 2007-11-29 | 2007-11-29 | Stable and soluble antibodies inhibiting tnfa |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MYPI20072131A MY164890A (en) | 2007-11-29 | 2007-11-29 | Stable and soluble antibodies inhibiting tnfa |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY164890A true MY164890A (en) | 2018-01-30 |
Family
ID=62117205
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI20072131A MY164890A (en) | 2007-11-29 | 2007-11-29 | Stable and soluble antibodies inhibiting tnfa |
Country Status (1)
| Country | Link |
|---|---|
| MY (1) | MY164890A (en) |
-
2007
- 2007-11-29 MY MYPI20072131A patent/MY164890A/en unknown
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