MY173426A - A system for identifying presence of polynucleotides of interest from a sample - Google Patents
A system for identifying presence of polynucleotides of interest from a sampleInfo
- Publication number
- MY173426A MY173426A MYPI2011700155A MYPI2011700155A MY173426A MY 173426 A MY173426 A MY 173426A MY PI2011700155 A MYPI2011700155 A MY PI2011700155A MY PI2011700155 A MYPI2011700155 A MY PI2011700155A MY 173426 A MY173426 A MY 173426A
- Authority
- MY
- Malaysia
- Prior art keywords
- sample
- layer
- operating circuit
- polynucleotides
- sensing platform
- Prior art date
Links
- 108091033319 polynucleotide Proteins 0.000 title abstract 4
- 102000040430 polynucleotide Human genes 0.000 title abstract 4
- 239000002157 polynucleotide Substances 0.000 title abstract 4
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 abstract 6
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 abstract 5
- 239000000523 sample Substances 0.000 abstract 4
- 229910052737 gold Inorganic materials 0.000 abstract 3
- 239000010931 gold Substances 0.000 abstract 3
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 abstract 2
- 238000009396 hybridization Methods 0.000 abstract 2
- 229910052759 nickel Inorganic materials 0.000 abstract 2
- 108020005187 Oligonucleotide Probes Proteins 0.000 abstract 1
- 230000000295 complement effect Effects 0.000 abstract 1
- 229910052802 copper Inorganic materials 0.000 abstract 1
- 239000010949 copper Substances 0.000 abstract 1
- 230000013011 mating Effects 0.000 abstract 1
- 239000002751 oligonucleotide probe Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
- G01N27/3275—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
- G01N27/3276—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction being a hybridisation with immobilised receptors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
A system for identifying presence of polynucleotides of interest from a sample comprising a sensing platform having a working electrode (102), a reference electrode (103) and a counter electrode (104) which are electrically connected to a connection port (101) and that the electrodes (102, 103, 104) have a top and a bottom layer respectively made of gold (111) and nickel (112), wherein surface of each layer of gold (111) is anchored with one or more oligonucleotide probes to readily hybridize with a substantially complementary polynucleotide in the sample; an operating circuit (105) provided with a receptive port to adaptably communicate with the sensing platform by mating with the connection port (101) and configured to measure a signal indicative of hybridization of the sensing platform; a display (108) connected to the operating circuit to acquire and show electrical readings of the operating circuit (105); wherein presence of polynucleotides of interest in the sample is identified by detecting the signal upon hybridization onto the probes; characterized in that the layer of nickel (112) is in between the layer of gold (111) and a base layer (109) made of copper (113) where the sensing platform and operating circuit are fabricated on.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MYPI2011700155A MY173426A (en) | 2011-10-19 | 2011-10-19 | A system for identifying presence of polynucleotides of interest from a sample |
| PCT/MY2011/000244 WO2013058646A1 (en) | 2011-10-19 | 2011-12-15 | A system for identifying presence of polynucleotides of interest from a sample |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MYPI2011700155A MY173426A (en) | 2011-10-19 | 2011-10-19 | A system for identifying presence of polynucleotides of interest from a sample |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY173426A true MY173426A (en) | 2020-01-23 |
Family
ID=48141152
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI2011700155A MY173426A (en) | 2011-10-19 | 2011-10-19 | A system for identifying presence of polynucleotides of interest from a sample |
Country Status (2)
| Country | Link |
|---|---|
| MY (1) | MY173426A (en) |
| WO (1) | WO2013058646A1 (en) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6761816B1 (en) * | 1998-06-23 | 2004-07-13 | Clinical Micro Systems, Inc. | Printed circuit boards with monolayers and capture ligands |
| EP1278821A4 (en) * | 2000-05-03 | 2005-11-09 | Jen Gau Jr | BIOLOGICAL IDENTIFICATION SYSTEM WITH INTEGRATED SENSOR CHIP |
| US20080087554A1 (en) * | 2006-05-24 | 2008-04-17 | Antara Biosciences Inc. | Electrochemical detection device |
| CN101779122A (en) * | 2007-08-01 | 2010-07-14 | 尼普洛株式会社 | Mental stress measurement kit and mental stress measurement method |
-
2011
- 2011-10-19 MY MYPI2011700155A patent/MY173426A/en unknown
- 2011-12-15 WO PCT/MY2011/000244 patent/WO2013058646A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2013058646A1 (en) | 2013-04-25 |
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