MY176214A - Three-pack type dialysis agent containing acetic acid and acetic acid salt - Google Patents
Three-pack type dialysis agent containing acetic acid and acetic acid saltInfo
- Publication number
- MY176214A MY176214A MYPI2016701187A MYPI2016701187A MY176214A MY 176214 A MY176214 A MY 176214A MY PI2016701187 A MYPI2016701187 A MY PI2016701187A MY PI2016701187 A MYPI2016701187 A MY PI2016701187A MY 176214 A MY176214 A MY 176214A
- Authority
- MY
- Malaysia
- Prior art keywords
- acetic acid
- agent
- pack type
- dialysis fluid
- bicarbonate
- Prior art date
Links
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 title abstract 15
- 239000003795 chemical substances by application Substances 0.000 title abstract 10
- 238000000502 dialysis Methods 0.000 title abstract 4
- 125000000218 acetic acid group Chemical class C(C)(=O)* 0.000 title 1
- 239000000385 dialysis solution Substances 0.000 abstract 5
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 4
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 abstract 3
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 3
- 239000008103 glucose Substances 0.000 abstract 3
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 abstract 2
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 abstract 2
- 150000001242 acetic acid derivatives Chemical class 0.000 abstract 2
- 239000004615 ingredient Substances 0.000 abstract 2
- 239000011780 sodium chloride Substances 0.000 abstract 2
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 abstract 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- JLVVSXFLKOJNIY-UHFFFAOYSA-N Magnesium ion Chemical compound [Mg+2] JLVVSXFLKOJNIY-UHFFFAOYSA-N 0.000 abstract 1
- UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical compound [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 abstract 1
- 229910001424 calcium ion Inorganic materials 0.000 abstract 1
- 239000003792 electrolyte Substances 0.000 abstract 1
- 229910001425 magnesium ion Inorganic materials 0.000 abstract 1
- 229910001414 potassium ion Inorganic materials 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 235000017557 sodium bicarbonate Nutrition 0.000 abstract 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 abstract 1
- 229910021655 trace metal ion Inorganic materials 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1654—Dialysates therefor
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Emergency Medicine (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- External Artificial Organs (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Abstract
The purpose of the present invention is to provide a three-pack type dialysis agent with which it is possible to set the total acetic acid ion content in a dialysis fluid at a low value and which is excellent in terms of the storage stability of glucose, etc. and can be reduced in the odor of acetic acid. Therewith, it is possible to prepare a dialysis fluid so that the bicarbonate ion concentration can be changed at will according to need, while the concentrations of trace metal ions such as potassium ions, calcium ions, and magnesium ions are kept constant. The three-pack type dialysis agent comprises agent S comprising sodium chloride, agent B comprising sodium bicarbonate, and agent A containing glucose and an electrolyte ingredient which is neither sodium chloride nor sodium bicarbonate. By making the agent A contain acetic acid and an acetic acid salt and satisfy that the molar ratio of acetic acid/acetic acid salt is 1/(0.5-2), a bicarbonate dialysis fluid having a total acetic acid ion concentration of 2 mEq/L or higher but less than 6 mEq/L can be prepared. This agent A not only is excellent in terms of the stability of the ingredients including glucose but also can be reduced in the odor of acetic acid. According to the three-pack type dialysis agent, by controlling the amounts of the agents S, B, and A to be added when preparing a dialysis fluid, the bicarbonate ion concentration and/or sodium concentration in the dialysis fluid can be also changed.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2013207382A JP5517322B1 (en) | 2013-10-02 | 2013-10-02 | Three-part dialysis agent containing acetic acid and acetate |
| PCT/JP2014/076373 WO2015050189A1 (en) | 2013-10-02 | 2014-10-02 | Three-pack type dialysis agent containing acetic acid and acetic acid salt |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY176214A true MY176214A (en) | 2020-07-24 |
Family
ID=51031258
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI2016701187A MY176214A (en) | 2013-10-02 | 2014-10-02 | Three-pack type dialysis agent containing acetic acid and acetic acid salt |
| MYPI2016701186A MY178249A (en) | 2013-10-02 | 2014-10-02 | Solid dialysis a agent containing alkali metal diacetate, and two-part type low-acetate dialysis agent using same |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI2016701186A MY178249A (en) | 2013-10-02 | 2014-10-02 | Solid dialysis a agent containing alkali metal diacetate, and two-part type low-acetate dialysis agent using same |
Country Status (6)
| Country | Link |
|---|---|
| JP (1) | JP5517322B1 (en) |
| KR (1) | KR102363179B1 (en) |
| MY (2) | MY176214A (en) |
| PH (1) | PH12016500571B1 (en) |
| SG (1) | SG11201602533QA (en) |
| WO (1) | WO2015050189A1 (en) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5376480B1 (en) | 2012-10-10 | 2013-12-25 | 富田製薬株式会社 | A dialysis agent containing acetic acid and acetate, and two-agent dialysis agent using the same |
| JP5517321B1 (en) * | 2013-10-02 | 2014-06-11 | 富田製薬株式会社 | Solid dialysis agent A containing alkali metal diacetate, and two-agent type low-acetate dialysis agent using the same |
| JPWO2015072494A1 (en) | 2013-11-12 | 2017-03-16 | 扶桑薬品工業株式会社 | Novel sodium diacetate crystal and solid dialysis preparation containing the crystal |
| JP6562336B2 (en) * | 2014-12-11 | 2019-08-21 | 富田製薬株式会社 | Method for producing granulated material used for dialysis agent A |
| KR102624996B1 (en) * | 2015-03-31 | 2024-01-12 | 감브로 룬디아 아베 | Package for acid dialysate concentrate containing citrate and glucose |
| JP6467285B2 (en) * | 2015-05-13 | 2019-02-13 | 富田製薬株式会社 | Granules for agent A for dialysis and method for producing the same |
| JP6312957B1 (en) * | 2016-10-28 | 2018-04-18 | 富田製薬株式会社 | Agent A for hemodialysis |
| WO2018079022A1 (en) * | 2016-10-28 | 2018-05-03 | 富田製薬株式会社 | Hemodialysis agent a |
| CN110522763A (en) * | 2019-10-08 | 2019-12-03 | 四川太平洋药业有限责任公司 | A kind of Multiple electrolytes injection and preparation process |
| CN117838624A (en) * | 2023-11-29 | 2024-04-09 | 南京红太阳医药研究院有限公司 | A kind of Procaterol hydrochloride oral solution and preparation method thereof |
| CN119564851B (en) * | 2024-12-05 | 2025-08-22 | 广州骐骥生物科技有限公司 | A glacial acetic acid dialysis concentrate and its preparation method |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0599464A (en) | 1991-10-08 | 1993-04-20 | Nec Corp | Air shower device |
| ES2149793T5 (en) | 1993-02-19 | 2005-03-01 | Wilfried Dr.-Ing. Schal | PROCEDURE FOR THE PREPARATION OF BICARBONATED DIALIZER LIQUID FOR HEMODIALISIS. |
| JP2809971B2 (en) | 1993-07-06 | 1998-10-15 | 扶桑薬品工業株式会社 | Hemodialysis preparation |
| JP3433979B2 (en) * | 1993-08-24 | 2003-08-04 | 日機装株式会社 | Dialysis agent and method for producing the same |
| JP3619921B2 (en) | 1996-09-13 | 2005-02-16 | 富田製薬株式会社 | Bicarbonate solid dialysis agent |
| WO1999009953A1 (en) * | 1997-08-22 | 1999-03-04 | Shimizu Pharmaceutical Co., Ltd. | Glucose-containing preparation |
| JP3586767B2 (en) * | 2000-04-06 | 2004-11-10 | 富田製薬株式会社 | Preparation method and adjustment device for dialysate |
| JP5204359B2 (en) | 2001-09-28 | 2013-06-05 | 味の素株式会社 | Dialysis agent and method for producing the same |
| CN1189180C (en) * | 2003-04-30 | 2005-02-16 | 广州康盛生物科技有限公司 | Bicarbonate dry powder composition for hemodialysis |
| US20070231395A1 (en) | 2004-03-30 | 2007-10-04 | Toshiya Kai | Solid Pharmaceutical Preparation for Dialysis |
| WO2010112570A1 (en) | 2009-03-31 | 2010-10-07 | Gambro Lundia Ab | Dialysis solution |
| JP5099464B1 (en) * | 2011-12-29 | 2012-12-19 | 富田製薬株式会社 | Bicarbonate ion concentration-variable dialysate preparation device and preparation method, bicarbonate ion concentration-variable dialysate, and bicarbonate ion concentration-variable dialyzing system |
-
2013
- 2013-10-02 JP JP2013207382A patent/JP5517322B1/en active Active
-
2014
- 2014-10-02 SG SG11201602533QA patent/SG11201602533QA/en unknown
- 2014-10-02 WO PCT/JP2014/076373 patent/WO2015050189A1/en not_active Ceased
- 2014-10-02 MY MYPI2016701187A patent/MY176214A/en unknown
- 2014-10-02 KR KR1020167011118A patent/KR102363179B1/en active Active
- 2014-10-02 MY MYPI2016701186A patent/MY178249A/en unknown
-
2016
- 2016-03-29 PH PH12016500571A patent/PH12016500571B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PH12016500571A1 (en) | 2016-06-20 |
| KR20160064181A (en) | 2016-06-07 |
| JP5517322B1 (en) | 2014-06-11 |
| SG11201602533QA (en) | 2016-05-30 |
| PH12016500571B1 (en) | 2016-06-20 |
| WO2015050189A1 (en) | 2015-04-09 |
| MY178249A (en) | 2020-10-07 |
| JP2015070908A (en) | 2015-04-16 |
| KR102363179B1 (en) | 2022-02-14 |
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