MY193623A - Method for producing a pharmaceutically stable composition presented as an aqueous solution - Google Patents

Method for producing a pharmaceutically stable composition presented as an aqueous solution

Info

Publication number
MY193623A
MY193623A MYPI2019001541A MYPI2019001541A MY193623A MY 193623 A MY193623 A MY 193623A MY PI2019001541 A MYPI2019001541 A MY PI2019001541A MY PI2019001541 A MYPI2019001541 A MY PI2019001541A MY 193623 A MY193623 A MY 193623A
Authority
MY
Malaysia
Prior art keywords
producing
aqueous solution
composition presented
tris
minutes
Prior art date
Application number
MYPI2019001541A
Inventor
Alexey Leonidovich Kovalenko
Andrey Yurievich Petrov
Original Assignee
Obschestvo S Ogranichennoi Otvetstvennostyu Nauchno Tehnologicheskaya Farm Firma Polysan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Obschestvo S Ogranichennoi Otvetstvennostyu Nauchno Tehnologicheskaya Farm Firma Polysan filed Critical Obschestvo S Ogranichennoi Otvetstvennostyu Nauchno Tehnologicheskaya Farm Firma Polysan
Publication of MY193623A publication Critical patent/MY193623A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention relates to chemical and pharmaceutical industry and, in particular, to a method for producing a stabilized pharmaceutical composition presented as an aqueous solution that may be used to obtain an intravenous drug containing succinic acid, nicotinamide, inosine and riboflavin mononucleotide as the active ingredients and possessing cytoprotective properties. In accordance with the invention, the composition is supplemented by one or several of the pharmaceutically acceptable components as the stabilizing agent to be selected from the group including sodium hydroxide, tris(hydroxymethyl)aminomethane (TRIS), ethanolamine, diethanolamine, sodium carbonate, meglumine, up to a stable solution with pH from 6.0 to 8.0, the components? ratio,%wt, and the solution is subjected to additional thermal sterilization at 100?? with exposure time of 8 minutes to 116?? with exposure time of 2 minutes.
MYPI2019001541A 2016-09-29 2017-09-07 Method for producing a pharmaceutically stable composition presented as an aqueous solution MY193623A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
RU2016138632A RU2629204C1 (en) 2016-09-29 2016-09-29 Method for obtaining of stabilized pharmaceutical composition as aqueous solution
PCT/RU2017/000658 WO2018063028A1 (en) 2016-09-29 2017-09-07 Method for producing a stabilized pharmaceutical composition in the form of an aqueous solution

Publications (1)

Publication Number Publication Date
MY193623A true MY193623A (en) 2022-10-20

Family

ID=59744837

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI2019001541A MY193623A (en) 2016-09-29 2017-09-07 Method for producing a pharmaceutically stable composition presented as an aqueous solution

Country Status (16)

Country Link
CN (1) CN110022858B (en)
AR (1) AR109775A1 (en)
BR (1) BR112019006167A2 (en)
CL (1) CL2019000810A1 (en)
CO (1) CO2019004133A2 (en)
EA (1) EA029693B1 (en)
EC (1) ECSP19030392A (en)
GE (1) GEP20207194B (en)
MD (1) MD4774C1 (en)
MY (1) MY193623A (en)
PH (1) PH12019500702A1 (en)
PY (1) PY1773438A (en)
RU (1) RU2629204C1 (en)
UA (1) UA118387C2 (en)
UY (1) UY37426A (en)
WO (1) WO2018063028A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2651047C1 (en) * 2017-05-04 2018-04-18 Общество С Ограниченной Ответственностью "Научно-Технологическая Фармацевтическая Фирма "Полисан" Drug composition of cytoprotective action and method for production thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2059417C1 (en) * 1992-10-01 1996-05-10 Данилевич Василий Николаевич Method for sterilization of nutrient media
KR20010033563A (en) * 1997-12-25 2001-04-25 다카하시 데츠로 Water-base liquid preparation
EA001099B1 (en) * 1999-06-10 2000-10-30 Общество С Ограниченной Ответственностью "Научно-Технологическая Фармацевтическая Фирма "Полисан" Injecting medical preparation "citoflavin" possessing cito-pretecting effect
JP2002161047A (en) * 2000-11-28 2002-06-04 Terumo Corp Hemoglobin solution and liposomes containing hemoglobin
RU2238108C1 (en) * 2003-01-27 2004-10-20 Нестерук Владимир Викторович Method for sterilizing sodium chloride injection solution
CN1679615A (en) * 2005-02-04 2005-10-12 北京阜康仁生物制药科技有限公司 Compound infantile energy mistura soluble vitamin preparation and use thereof
CN101601647B (en) * 2009-07-09 2010-09-15 周晓东 Riboflavine sodium phosphate composition injection and preparation method thereof
RU2536994C1 (en) * 2013-05-17 2014-12-27 Общество С Ограниченной Ответственностью "Нпо "Нефрон" Concentrated acidic component, kit for producing it, concentrated solution of acidic component for producing hemodialysis solution and method for producing it
WO2015113035A1 (en) * 2014-01-27 2015-07-30 Abbott Laboratories Aseptic filtration process
WO2015126942A1 (en) * 2014-02-18 2015-08-27 Glenn Abrahmsohn Compositions and methods for pain relief without numbness
EP3268746B1 (en) * 2015-03-12 2024-07-17 Mars, Incorporated Ultra high resolution mass spectrometry and methods of using the same

Also Published As

Publication number Publication date
MD4774C1 (en) 2022-06-30
MD20190038A2 (en) 2019-10-31
CN110022858B (en) 2021-12-14
GEAP202015060A (en) 2020-08-25
EA201700072A1 (en) 2018-03-30
MD4774B1 (en) 2021-11-30
RU2629204C1 (en) 2017-08-25
UA118387C2 (en) 2019-01-10
BR112019006167A2 (en) 2019-06-18
AR109775A1 (en) 2019-01-23
CL2019000810A1 (en) 2019-08-02
CO2019004133A2 (en) 2019-09-30
CN110022858A (en) 2019-07-16
PH12019500702A1 (en) 2019-11-25
WO2018063028A1 (en) 2018-04-05
ECSP19030392A (en) 2019-08-30
UY37426A (en) 2018-04-30
PY1773438A (en) 2019-04-01
GEP20207194B (en) 2020-12-25
EA029693B1 (en) 2018-04-30

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