MY194438A - Modified streptomyces fungicidicus isolates and their use - Google Patents
Modified streptomyces fungicidicus isolates and their useInfo
- Publication number
- MY194438A MY194438A MYPI2019002918A MYPI2019002918A MY194438A MY 194438 A MY194438 A MY 194438A MY PI2019002918 A MYPI2019002918 A MY PI2019002918A MY PI2019002918 A MYPI2019002918 A MY PI2019002918A MY 194438 A MY194438 A MY 194438A
- Authority
- MY
- Malaysia
- Prior art keywords
- isolates
- streptomyces fungicidicus
- modified streptomyces
- modified
- fungicidicus
- Prior art date
Links
- 241000971005 Streptomyces fungicidicus Species 0.000 title abstract 3
- NJCUSQKMYNTYOW-MWUYRYRWSA-N enramicina Chemical compound O.N1C(=O)NC(=O)C(C=2C=C(Cl)C(O)=C(Cl)C=2)NC(=O)C(CO)NC(=O)C(C=2C=CC(O)=CC=2)NC(=O)C(CC2N=C(N)NC2)NC(=O)C(CCCNC(N)=O)NC(=O)C(C(C)O)NC(=O)C(C=2C=CC(O)=CC=2)NC(=O)C(C=2C=CC(O)=CC=2)NC(=O)C(C(C)O)NC(=O)N(CCCCN)C(=O)C(C=2C=CC(O)=CC=2)NC(=O)C(NC(=O)C(CC(O)=O)NC(=O)/C=C/C=C/CCCCC(C)CC)C(C)OC(=O)C(C=2C=CC(O)=CC=2)NC(=O)C(C)NC(=O)C1CC1CNC(N)=N1 NJCUSQKMYNTYOW-MWUYRYRWSA-N 0.000 abstract 2
- 229950003984 enramycin Drugs 0.000 abstract 2
- 108700041171 enramycin Proteins 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/36—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Actinomyces; from Streptomyces (G)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Abstract
The present invention is drawn to modified Streptomyces fungicidicus isolates, to compositions comprising these isolates, and methods of using such isolates and compositions to biologically synthesize enduracidin (enramycin). In addition, the present invention is drawn to modified Streptomyces fungicidicus isolates that biologically synthesize enduracidin and facilitate the production of enramycin in a more efficient manner. [Fig 1]
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662430455P | 2016-12-06 | 2016-12-06 | |
| PCT/EP2017/073771 WO2018103905A1 (en) | 2016-12-06 | 2017-09-20 | Modified streptomyces fungicidicus isolates and their use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY194438A true MY194438A (en) | 2022-11-30 |
Family
ID=60043150
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI2019002918A MY194438A (en) | 2016-12-06 | 2017-09-20 | Modified streptomyces fungicidicus isolates and their use |
Country Status (11)
| Country | Link |
|---|---|
| JP (2) | JP2020500509A (en) |
| CN (1) | CN110072881A (en) |
| BR (1) | BR112019011603A2 (en) |
| CO (1) | CO2019005540A2 (en) |
| MX (1) | MX2019006586A (en) |
| MY (1) | MY194438A (en) |
| PE (1) | PE20190967A1 (en) |
| PH (1) | PH12019501225A1 (en) |
| TW (1) | TWI770070B (en) |
| UA (1) | UA127451C2 (en) |
| WO (1) | WO2018103905A1 (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2019006522A (en) | 2016-12-06 | 2020-02-20 | Univ Oregon State | Compositions and methods for enhanced production of enduracidin in a genetically engineered strain of streptomyces fungicidicus. |
| CN115261258A (en) * | 2022-06-07 | 2022-11-01 | 四川汇邦环保科技有限公司 | Microbial agent for degrading duramycin |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT269354B (en) * | 1965-10-13 | 1969-03-10 | Takeda Chemical Industries Ltd | Process for the production of a new antibiotic |
| DE1617881C2 (en) | 1965-10-13 | 1984-07-05 | Takeda Chemical Industries, Ltd., Osaka | Antibiotic enduracidin and its manufacture |
| US3577530A (en) | 1969-07-24 | 1971-05-04 | Squibb & Sons Inc | Janiemycin |
| JPS6038120B2 (en) * | 1980-10-31 | 1985-08-30 | 武田薬品工業株式会社 | Production method of the antibiotic enzyuracydin |
| US8188245B2 (en) | 2006-09-29 | 2012-05-29 | State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University | Enduracidin biosynthetic gene cluster from streptomyces fungicidicus |
| CN101974469B (en) * | 2010-10-22 | 2012-05-23 | 安徽丰原发酵技术工程研究有限公司 | Streptomyces fungicidious mutant strain and application thereof |
| CN103374537B (en) * | 2012-04-25 | 2015-01-07 | 牡丹江佰佳信生物科技有限公司 | Method for preparing enduracidin and strain produced thereby |
| CN102864114B (en) * | 2012-10-19 | 2013-11-06 | 河北圣雪大成制药有限责任公司 | Strain for highly yielding enramycin, and preparation method and application thereof |
| CN103740612A (en) * | 2013-12-19 | 2014-04-23 | 河北圣雪大成制药有限责任公司 | High-yield enramycin strain and screening method thereof |
-
2017
- 2017-09-20 MX MX2019006586A patent/MX2019006586A/en unknown
- 2017-09-20 BR BR112019011603-6A patent/BR112019011603A2/en not_active Application Discontinuation
- 2017-09-20 UA UAA201906560A patent/UA127451C2/en unknown
- 2017-09-20 MY MYPI2019002918A patent/MY194438A/en unknown
- 2017-09-20 CN CN201780073894.9A patent/CN110072881A/en active Pending
- 2017-09-20 WO PCT/EP2017/073771 patent/WO2018103905A1/en not_active Ceased
- 2017-09-20 PE PE2019001065A patent/PE20190967A1/en unknown
- 2017-09-20 JP JP2019524442A patent/JP2020500509A/en not_active Ceased
- 2017-10-11 TW TW106134804A patent/TWI770070B/en not_active IP Right Cessation
-
2019
- 2019-05-28 CO CONC2019/0005540A patent/CO2019005540A2/en unknown
- 2019-05-31 PH PH12019501225A patent/PH12019501225A1/en unknown
-
2022
- 2022-11-10 JP JP2022180156A patent/JP2023012549A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2023012549A (en) | 2023-01-25 |
| UA127451C2 (en) | 2023-08-30 |
| TWI770070B (en) | 2022-07-11 |
| JP2020500509A (en) | 2020-01-16 |
| PE20190967A1 (en) | 2019-07-08 |
| WO2018103905A1 (en) | 2018-06-14 |
| PH12019501225A1 (en) | 2019-09-23 |
| RU2019117260A (en) | 2021-01-11 |
| TW201827590A (en) | 2018-08-01 |
| CN110072881A (en) | 2019-07-30 |
| MX2019006586A (en) | 2019-08-22 |
| RU2019117260A3 (en) | 2021-01-29 |
| BR112019011603A2 (en) | 2020-08-18 |
| CO2019005540A2 (en) | 2019-05-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PH12018501226A1 (en) | Methods for treating huntingtons disease | |
| WO2017214170A3 (en) | Baff-r antibodies and uses thereof | |
| EP4541361A3 (en) | Treatment of cancer by manipulation of commensal microflora | |
| MX2022001755A (en) | Cyclic di-nucleotide compounds and methods of use. | |
| SG10201803042PA (en) | Anti-tim-3 antibodies | |
| AU2018335389A1 (en) | Nanofiber structures and methods of use thereof | |
| MX2019007020A (en) | Il-11 antibodies. | |
| MX2019009117A (en) | Antibodies to alpha-synuclein and uses thereof. | |
| WO2017136450A3 (en) | Compounds and methods of treating rna-mediated diseases | |
| MY196319A (en) | Polycyclic TLR7/8 Antagonists and use Thereof in the Treatment of Immune Disorders | |
| EP4516319A3 (en) | Subcutaneous formulations of anti-cd38 antibodies and their uses | |
| EP4268892A3 (en) | Matrix bound nanovesicles and their use | |
| MY194603A (en) | Anti-Complement Factor Bb Antibodies And Uses Thereof | |
| MY191581A (en) | Anti-pd-1 antibodies | |
| AU366476S (en) | Bottle | |
| MY201811A (en) | Method of reducing neutropenia | |
| MX2016016143A (en) | Substituted [1,2,4]triazole compounds. | |
| TN2019000075A1 (en) | Anti-cd27 antibodies | |
| MY193650A (en) | Extracellular matrix compositions | |
| WO2019108871A8 (en) | Biofouling resistant coatings and methods of making and using the same | |
| ZA201803476B (en) | Anti-cd22 antibody-maytansine conjugates and methods of use thereof | |
| WO2020127145A3 (en) | Materials for electronic devices | |
| EP4574832A3 (en) | Dantrolene prodrugs and methods of their use | |
| SG10201805646WA (en) | Angiopoietin-like 4 antibodies and methods of use | |
| MX2020000636A (en) | Synthetic proteins and therapeutic uses thereof. |