MY197202A - A liquid formulation of anti-tnf alpha antibody - Google Patents
A liquid formulation of anti-tnf alpha antibodyInfo
- Publication number
- MY197202A MY197202A MYPI2019005331A MYPI2019005331A MY197202A MY 197202 A MY197202 A MY 197202A MY PI2019005331 A MYPI2019005331 A MY PI2019005331A MY PI2019005331 A MYPI2019005331 A MY PI2019005331A MY 197202 A MY197202 A MY 197202A
- Authority
- MY
- Malaysia
- Prior art keywords
- liquid formulation
- tnf alpha
- alpha antibody
- antibody
- tnf
- Prior art date
Links
- 239000012669 liquid formulation Substances 0.000 title abstract 3
- 229960002964 adalimumab Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39591—Stabilisation, fragmentation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
- A61K40/4231—Cytokines
- A61K40/4232—Tumor necrosis factors [TNF] or CD70
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Immunology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Endocrinology (AREA)
- Biomedical Technology (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
Abstract
The present invention relates to a liquid formulation of an anti-TNF-? antibody, specifically to a liquid formulation of adalimumab. The most illustrative drawing: FIGURE 2
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20170033188 | 2017-03-16 | ||
| PCT/KR2018/003097 WO2018169348A1 (en) | 2017-03-16 | 2018-03-16 | Liquid formulation of anti-tnf alpha antibody |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY197202A true MY197202A (en) | 2023-05-31 |
Family
ID=63522490
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI2019005331A MY197202A (en) | 2017-03-16 | 2018-03-16 | A liquid formulation of anti-tnf alpha antibody |
Country Status (14)
| Country | Link |
|---|---|
| JP (2) | JP7109849B2 (en) |
| KR (2) | KR20180106974A (en) |
| CN (1) | CN110621303A (en) |
| AU (1) | AU2018236651B2 (en) |
| CO (1) | CO2019010860A2 (en) |
| MA (1) | MA46988A1 (en) |
| MX (1) | MX2019010895A (en) |
| MY (1) | MY197202A (en) |
| NZ (1) | NZ757965A (en) |
| PH (1) | PH12019502075A1 (en) |
| RU (1) | RU2756619C2 (en) |
| UA (1) | UA123847C2 (en) |
| WO (1) | WO2018169348A1 (en) |
| ZA (1) | ZA201906696B (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN120241997A (en) * | 2019-02-18 | 2025-07-04 | 伊莱利利公司 | Therapeutic antibody preparations |
| CN113727730A (en) * | 2019-03-18 | 2021-11-30 | 阿尔沃科技Hf公司 | Aqueous formulations of high concentration TNF alpha antibodies |
| TW202519263A (en) * | 2019-03-21 | 2025-05-16 | 美商再生元醫藥公司 | Stabilized formulations containing anti-il-33 antibodies |
| EP4108258A4 (en) * | 2020-02-20 | 2024-03-06 | Bio-Thera Solutions, Ltd. | Anti-tnf-alpha antibody preparation, preparation method therefor and use thereof |
| JP2023533704A (en) * | 2020-07-13 | 2023-08-04 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | Viscosity-reducing excipients and combinations thereof for high-concentration protein formulations |
| WO2022178114A1 (en) * | 2021-02-17 | 2022-08-25 | Aptevo Research And Development Llc | Compositions comprising 4-1bb and ox40 binding proteins and methods of use |
| JPWO2025013783A1 (en) | 2023-07-07 | 2025-01-16 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8821865B2 (en) * | 2010-11-11 | 2014-09-02 | Abbvie Biotechnology Ltd. | High concentration anti-TNFα antibody liquid formulations |
| UY34105A (en) * | 2011-06-03 | 2012-07-31 | Lg Life Sciences Ltd | STABLE LIQUID FORMULATION OF ETANERCEPT |
| JP2015509526A (en) * | 2012-03-07 | 2015-03-30 | カディラ ヘルスケア リミティド | Pharmaceutical formulation |
| PE20150964A1 (en) | 2012-09-07 | 2015-07-25 | Coherus Biosciences Inc | STABLE AQUEOUS FORMULATIONS OF ADALIMUMAB |
| BR112015017619A2 (en) * | 2013-01-24 | 2017-11-21 | Glaxosmithkline Ip Dev Ltd | liquid formulation, use of a formulation, and kit |
| TW201513882A (en) | 2013-03-15 | 2015-04-16 | Bayer Healthcare Llc | Anti-prolactin receptor antibody formulations |
| WO2015134406A1 (en) | 2014-03-03 | 2015-09-11 | La Jolla Biologics, Inc. | Stable aqueous recombinant protein formulations |
| WO2015151115A1 (en) * | 2014-04-02 | 2015-10-08 | Intas Pharmaceuticals Limited | Liquid pharmaceutical composition of adalimumab |
| PT2946765T (en) * | 2014-05-23 | 2016-11-10 | Ares Trading Sa | Liquid pharmaceutical composition |
| US9821059B2 (en) | 2014-10-17 | 2017-11-21 | Alteogen Inc. | Composition for stabilizing protein and pharmaceutical formulation comprising the same |
| HUP1400510A1 (en) * | 2014-10-28 | 2016-05-30 | Richter Gedeon Nyrt | Pharmaceutical anti-tnfalpha antibody formulation |
| US20180016333A1 (en) * | 2015-01-28 | 2018-01-18 | Mabxience, S.A. | Pharmaceutical formulations for anti-tnf-alpha antibodies |
| WO2016162819A1 (en) * | 2015-04-07 | 2016-10-13 | Lupin Limited | Stable aqueous pharmaceutical composition of anti-tnf alpha antibody |
-
2018
- 2018-03-16 MY MYPI2019005331A patent/MY197202A/en unknown
- 2018-03-16 MA MA46988A patent/MA46988A1/en unknown
- 2018-03-16 RU RU2019130728A patent/RU2756619C2/en active
- 2018-03-16 KR KR1020180031016A patent/KR20180106974A/en not_active Ceased
- 2018-03-16 AU AU2018236651A patent/AU2018236651B2/en active Active
- 2018-03-16 NZ NZ757965A patent/NZ757965A/en unknown
- 2018-03-16 UA UAA201909838A patent/UA123847C2/en unknown
- 2018-03-16 JP JP2019551275A patent/JP7109849B2/en active Active
- 2018-03-16 WO PCT/KR2018/003097 patent/WO2018169348A1/en not_active Ceased
- 2018-03-16 CN CN201880031705.6A patent/CN110621303A/en active Pending
- 2018-03-16 MX MX2019010895A patent/MX2019010895A/en unknown
-
2019
- 2019-09-12 PH PH12019502075A patent/PH12019502075A1/en unknown
- 2019-09-30 CO CONC2019/0010860A patent/CO2019010860A2/en unknown
- 2019-10-10 ZA ZA2019/06696A patent/ZA201906696B/en unknown
-
2020
- 2020-08-05 KR KR1020200098144A patent/KR102342292B1/en active Active
-
2022
- 2022-05-06 JP JP2022076654A patent/JP2022097600A/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| JP7109849B2 (en) | 2022-08-01 |
| RU2019130728A (en) | 2021-04-16 |
| CN110621303A (en) | 2019-12-27 |
| KR102342292B1 (en) | 2021-12-24 |
| MA46988A1 (en) | 2020-06-30 |
| AU2018236651B2 (en) | 2020-12-10 |
| RU2756619C2 (en) | 2021-10-04 |
| WO2018169348A1 (en) | 2018-09-20 |
| AU2018236651A1 (en) | 2019-10-31 |
| KR20180106974A (en) | 2018-10-01 |
| BR112019019162A2 (en) | 2020-04-14 |
| PH12019502075A1 (en) | 2020-09-14 |
| CO2019010860A2 (en) | 2020-01-17 |
| UA123847C2 (en) | 2021-06-09 |
| MX2019010895A (en) | 2019-11-05 |
| JP2020510079A (en) | 2020-04-02 |
| RU2019130728A3 (en) | 2021-04-16 |
| JP2022097600A (en) | 2022-06-30 |
| KR20200096472A (en) | 2020-08-12 |
| ZA201906696B (en) | 2020-08-26 |
| NZ757965A (en) | 2022-07-01 |
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