MY198689A - The contorsbody � a single chain target binder - Google Patents

The contorsbody � a single chain target binder

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Publication number
MY198689A
MY198689A MYPI2018704034A MYPI2018704034A MY198689A MY 198689 A MY198689 A MY 198689A MY PI2018704034 A MYPI2018704034 A MY PI2018704034A MY PI2018704034 A MYPI2018704034 A MY PI2018704034A MY 198689 A MY198689 A MY 198689A
Authority
MY
Malaysia
Prior art keywords
domain
binding domain
contorsbody
single chain
polypeptide
Prior art date
Application number
MYPI2018704034A
Inventor
Dengl Stefan
Georges Guy
Hesse Friederike
Imhof-Jung Sabine
Platzer Josef
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Priority claimed from PCT/EP2017/060354 external-priority patent/WO2017191101A1/en
Publication of MY198689A publication Critical patent/MY198689A/en

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  • Peptides Or Proteins (AREA)

Abstract

Herein is reported a circular fusion polypeptide comprising a first part of a binding domain, a second part of a binding domain and a spacer domain, wherein the spacer domain is a polypeptide and comprises at least 25 amino acid residues, the first part of the binding domain is a polypeptide and is fused via a first linker to the N-terminus of the spacer domain, the second part of the binding domain is a polypeptide and is fused via a second linker to the C-terminus of the spacer domain, the first part of the binding domain and the second part of the binding domain are associated with each other and form a binding site that specifically binds to a target. [Figure 2A]
MYPI2018704034A 2016-05-02 2017-05-02 The contorsbody � a single chain target binder MY198689A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP17060354 2016-05-02
PCT/EP2017/060354 WO2017191101A1 (en) 2016-05-02 2017-05-02 The contorsbody - a single chain target binder

Publications (1)

Publication Number Publication Date
MY198689A true MY198689A (en) 2023-09-16

Family

ID=93211583

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI2018704034A MY198689A (en) 2016-05-02 2017-05-02 The contorsbody � a single chain target binder

Country Status (1)

Country Link
MY (1) MY198689A (en)

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