MY207971A - Immunogenic composition comprising multivalent streptococcus pneumoniae polysaccharide-protein conjugates - Google Patents

Immunogenic composition comprising multivalent streptococcus pneumoniae polysaccharide-protein conjugates

Info

Publication number
MY207971A
MY207971A MYPI2022000293A MYPI2022000293A MY207971A MY 207971 A MY207971 A MY 207971A MY PI2022000293 A MYPI2022000293 A MY PI2022000293A MY PI2022000293 A MYPI2022000293 A MY PI2022000293A MY 207971 A MY207971 A MY 207971A
Authority
MY
Malaysia
Prior art keywords
serotypes
immunogenic composition
present
capsular polysaccharides
protein conjugates
Prior art date
Application number
MYPI2022000293A
Inventor
Soo Young Lee
Pan Kyeom Kim
Jun Won Chwa
Ji Hyoun Cha
Wan Geun La
Kyung Min Jo
Original Assignee
Celltrion Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celltrion Inc filed Critical Celltrion Inc
Publication of MY207971A publication Critical patent/MY207971A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/385—Haptens or antigens, bound to carriers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)

Abstract

The present invention relates to an immunogenic composition including multivalent pneumococcal polysaccharide-protein conjugates. Each conjugate includes capsular polysaccharides of different pneumococcus serotypes conjugated to a carrier protein. More concretely, the present invention is a multivalent immunogenic composition including polysaccharide-protein conjugates. Each of the polysaccharide-protein conjugates includes Streptococcus pneumoniae-derived capsular polysaccharides of different serotypes conjugated to a carrier protein. The capsular polysaccharides include a) capsular polysaccharides of one or more serotypes selected from the group consisting of serotypes 1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F, and 23F, and b) capsular polysaccharides of one or more serotypes selected from the group consisting of serotypes 10A, 11A, 15B, 22F, 23A, and 35B. The multivalent immunogenic composition according to the present invention is capable of inducing an immune reaction against a wider variety of serotypes than the conventional Prevenar 13. In particular, the conventional Prevenar 13 is designed mainly for serotypes frequently appearing in Europe and North America, but the immunogenic composition of the present invention is an immunogenic composition having high coverage not only in Europe and North America but also throughout Asia. Therefore, the multivalent immunogenic composition according to the present invention is capable of being beneficially used to prevent diseases caused by pneumococcus in infants, children, and adults. (Figure 1)
MYPI2022000293A 2019-07-18 2020-07-17 Immunogenic composition comprising multivalent streptococcus pneumoniae polysaccharide-protein conjugates MY207971A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20190087004 2019-07-18
PCT/KR2020/009474 WO2021010798A1 (en) 2019-07-18 2020-07-17 Immunogenic composition comprising multivalent streptococcus pneumoniae polysaccharide-protein conjugates

Publications (1)

Publication Number Publication Date
MY207971A true MY207971A (en) 2025-03-31

Family

ID=74211166

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI2022000293A MY207971A (en) 2019-07-18 2020-07-17 Immunogenic composition comprising multivalent streptococcus pneumoniae polysaccharide-protein conjugates

Country Status (8)

Country Link
JP (1) JP7441301B2 (en)
KR (1) KR20210010412A (en)
CN (1) CN114364397B (en)
AU (1) AU2020315673B2 (en)
MY (1) MY207971A (en)
PH (1) PH12022550133A1 (en)
TW (1) TWI864052B (en)
WO (1) WO2021010798A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3074706A1 (en) * 2017-09-07 2019-03-14 Merck Sharp & Dohme Corp. Pneumococcal polysaccharides and their use in immunogenic polysaccharide-carrier protein conjugates
BR112020011414B8 (en) 2017-12-06 2023-01-31 Merck Sharp & Dohme MULTIVALENT IMMUNOGENIC COMPOSITIONS COMPRISING CARRIER PROTEIN AND POLYSACCHARIDE CONJUGATES FROM S. PNEUMONIAE
EP3897705A2 (en) 2018-12-19 2021-10-27 Merck Sharp & Dohme Corp. Compositions comprising streptococcus pneumoniae polysaccharide-protein conjugates and methods of use thereof
KR20220102871A (en) * 2021-01-14 2022-07-21 (주)셀트리온 The immunogenic composition comprising multivalent pneumococcal polysaccharide-protein conjugate
GB2614916A (en) * 2022-01-25 2023-07-26 Optivalent Ltd Intradermal vaccine complement
CN116942804A (en) * 2022-04-19 2023-10-27 上海瑞宙生物科技有限公司 Component of multivalent pneumococcal polysaccharide conjugate vaccine and application thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0620460B8 (en) * 2005-12-22 2021-05-25 Glaxosmithkline Biologicals Sa use of immunogenic composition for babies, and process to produce a vaccine
TW201136603A (en) * 2010-02-09 2011-11-01 Merck Sharp & Amp Dohme Corp 15-valent pneumococcal polysaccharide-protein conjugate vaccine composition
KR20210032013A (en) 2014-01-21 2021-03-23 화이자 인코포레이티드 Streptococcus pneumoniae capsular polysaccharides and conjugates thereof
CN104069504B (en) * 2014-05-11 2019-09-24 江苏康泰生物医学技术有限公司 A method of enhancing polysaccharide protein conjugate immunogenicity
PH12019500672B1 (en) * 2016-09-30 2024-02-23 Biological E Ltd Multivalent pneumococcal vaccine compositions comprising polysachharide-protein conjugates
MX2019007910A (en) 2016-12-30 2019-12-05 Sutrovax Inc POLYPEPTIDE-ANTIGEN CONJUGATES WITH NON-NATURAL AMINO ACIDS.
WO2018169303A1 (en) * 2017-03-15 2018-09-20 주식회사 엘지화학 Polyvalent streptococcus pneumoniae vaccine composition
CN108079286B (en) 2018-01-19 2020-07-31 云南沃森生物技术股份有限公司 13-valent pneumococcal polysaccharide-protein conjugate composition and preparation method and application thereof

Also Published As

Publication number Publication date
JP2022540718A (en) 2022-09-16
TW202116352A (en) 2021-05-01
AU2020315673B2 (en) 2025-01-23
CN114364397A (en) 2022-04-15
JP7441301B2 (en) 2024-02-29
AU2020315673A1 (en) 2022-02-10
TWI864052B (en) 2024-12-01
WO2021010798A1 (en) 2021-01-21
PH12022550133A1 (en) 2022-11-14
CN114364397B (en) 2024-03-29
KR20210010412A (en) 2021-01-27

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