MY209059A - Aqueous ophthalmic composition comprising diquafosol or salt thereof and polyvinylpyrrolidone - Google Patents
Aqueous ophthalmic composition comprising diquafosol or salt thereof and polyvinylpyrrolidoneInfo
- Publication number
- MY209059A MY209059A MYPI2022001012A MYPI2022001012A MY209059A MY 209059 A MY209059 A MY 209059A MY PI2022001012 A MYPI2022001012 A MY PI2022001012A MY PI2022001012 A MYPI2022001012 A MY PI2022001012A MY 209059 A MY209059 A MY 209059A
- Authority
- MY
- Malaysia
- Prior art keywords
- ophthalmic composition
- aqueous ophthalmic
- polyvinylpyrrolidone
- diquafosol
- salt
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7084—Compounds having two nucleosides or nucleotides, e.g. nicotinamide-adenine dinucleotide, flavine-adenine dinucleotide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
An aqueous ophthalmic composition comprising diquafosol or a salt thereof and polyvinylpyrrolidone. An aqueous ophthalmic composition for prevention or treatment of dry eye, comprising diquafosol sodium at a concentration of 3% (w/v), polyvinylpyrrolidone having a K value of 90, and silver nitrate, wherein the aqueous ophthalmic composition is used so as to be instilled into the eye 2 to 4 times a day in a dose of 1 or 2 drops each time. An aqueous ophthalmic composition for prevention or treatment of dry eye, comprising diquafosol sodium at a concentration of 3% (w/v), polyvinylpyrrolidone, and silver nitrate, the aqueous ophthalmic composition being used so as to be instilled into the eye 2 to 4 times a day in a dose of 1 or 2 drops each time, wherein the aqueous ophthalmic composition has a viscosity at 25C of 3 to 30 mPas.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2019154525 | 2019-08-27 | ||
| PCT/JP2020/031917 WO2021039748A1 (en) | 2019-08-27 | 2020-08-25 | Diquafosol or salt thereof, and aqueous ophthalmic composition containing polyvinylpyrrolidone |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY209059A true MY209059A (en) | 2025-06-18 |
Family
ID=74685901
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI2022001012A MY209059A (en) | 2019-08-27 | 2020-08-25 | Aqueous ophthalmic composition comprising diquafosol or salt thereof and polyvinylpyrrolidone |
Country Status (7)
| Country | Link |
|---|---|
| JP (3) | JP6966667B2 (en) |
| KR (2) | KR102656181B1 (en) |
| CN (2) | CN114286670B (en) |
| MY (1) | MY209059A (en) |
| PH (1) | PH12022550474A1 (en) |
| TW (1) | TWI848171B (en) |
| WO (1) | WO2021039748A1 (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117137866A (en) * | 2018-02-28 | 2023-12-01 | 参天制药株式会社 | Ophthalmic composition containing diquafosol and cationic polymer |
| JP6966667B2 (en) * | 2019-08-27 | 2021-11-17 | 参天製薬株式会社 | Aqueous ophthalmic composition containing diquafosol or a salt thereof, and polyvinylpyrrolidone. |
| CA3215750A1 (en) * | 2021-03-30 | 2022-10-06 | Senju Pharmaceutical Co., Ltd. | Suspension containing heterocyclidene acetamide derivative |
| CN114646705A (en) * | 2022-03-22 | 2022-06-21 | 武汉绿合医药科技有限公司 | Method for detecting content of related substances in diquafosol sodium eye drops |
| JP7245383B1 (en) | 2022-09-20 | 2023-03-23 | 参天製薬株式会社 | Method for Suppressing Decrease in pH of Ophthalmic Composition Containing Diquafosol or Its Salt |
| KR20250160050A (en) | 2024-05-03 | 2025-11-11 | 삼천당제약주식회사 | A pharmaceutical composition with improved physicochemical properties for preventing or treating dry eye syndrome |
| CN119970633A (en) * | 2025-03-26 | 2025-05-13 | 苏州乐珠制药有限公司 | Diquafosol sodium eye drops and preparation method thereof |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0365270A (en) | 1989-07-31 | 1991-03-20 | Kanzaki Paper Mfg Co Ltd | Manufacture of coated sheet |
| JPH0365270U (en) | 1989-10-31 | 1991-06-25 | ||
| US5358706A (en) * | 1992-09-30 | 1994-10-25 | Union Carbide Chemicals & Plastics Technology Corporation | Muco-adhesive polymers |
| CA2125060C (en) * | 1993-07-02 | 1999-03-30 | Henry P. Dabrowski | Ophthalmic solution for artificial tears |
| US5422116A (en) * | 1994-02-18 | 1995-06-06 | Ciba-Geigy Corporation | Liquid ophthalmic sustained release delivery system |
| US5900407A (en) * | 1997-02-06 | 1999-05-04 | Inspire Pharmaceuticals, Inc. | Method of treating dry eye disease with uridine triphosphates and related compounds |
| KR100549904B1 (en) * | 1996-03-27 | 2006-05-16 | 더 유니버시티 오브 노쓰 캐롤라이나 엣 채플 힐 | A pharmaceutical composition for treating ciliary dyskinesia, containing uridinde triphosphate and related compounds |
| US6274626B1 (en) * | 1998-12-22 | 2001-08-14 | Bausch & Lomb Incorporated | Pheniramine-containing compositions and method for treating allergic responses |
| AU2225701A (en) * | 1999-12-27 | 2001-07-09 | Santen Pharmaceutical Co. Ltd. | System for stabilizing lacrimal fluid layer |
| AU2001260643B9 (en) * | 2000-05-30 | 2006-10-19 | Merck Sharp & Dohme Corp. | Ectocornea extension promoters |
| KR20070114130A (en) * | 2005-02-14 | 2007-11-29 | 존슨 앤드 존슨 비젼 케어, 인코포레이티드 | A comfortable ophthalmic device and methods of its production |
| CN106729718A (en) * | 2010-09-10 | 2017-05-31 | 参天制药株式会社 | To combine P2Y2The dry eye treatment agent that receptor stimulating agent and hyaluronic acid or its salt are characterized |
| US20110052678A1 (en) * | 2010-11-05 | 2011-03-03 | Shantha Totada R | Method for treating age related macular degeneration |
| UA113839C2 (en) * | 2010-12-28 | 2017-03-27 | EYE SOLUTION CONTAINING DICVAFOSOL, METHOD OF ITS PREPARATION AND METHOD OF INHIBITION OF NON-SOLUTION DEPOSIT | |
| KR20120077080A (en) | 2010-12-30 | 2012-07-10 | 동우 화인켐 주식회사 | Optical film and backlight unit using the same |
| US20160213708A1 (en) * | 2012-01-08 | 2016-07-28 | Medicure Technologies Ltd. | Ophthalmic composition |
| KR101536885B1 (en) * | 2012-03-26 | 2015-07-14 | 산텐 세이야꾸 가부시키가이샤 | Diquafosol-containing eye drop |
| JP2015032653A (en) | 2013-08-01 | 2015-02-16 | 株式会社東芝 | Solid state imaging apparatus |
| JP6267003B2 (en) | 2014-02-27 | 2018-01-24 | 参天製薬株式会社 | Tear secretion promoter characterized by combining diquafosol or a salt thereof and rebamipide or a salt thereof |
| EP3139903B1 (en) * | 2014-05-07 | 2019-07-03 | Croma-Pharma Gesellschaft m.b.H. | Aqueous ophthalmic solution and method for treating dry eye syndrome |
| KR102330736B1 (en) * | 2014-12-25 | 2021-11-23 | 산텐 세이야꾸 가부시키가이샤 | Aqueous ophthalmic solution |
| CN107635565A (en) * | 2015-06-05 | 2018-01-26 | 参天制药株式会社 | A therapeutic agent for dry eye syndrome characterized by instillation into the eyes of dry eye patients wearing soft contact lenses |
| CN107837276A (en) * | 2016-09-19 | 2018-03-27 | 刘力 | The pharmaceutical composition being locally administered |
| CN117137866A (en) * | 2018-02-28 | 2023-12-01 | 参天制药株式会社 | Ophthalmic composition containing diquafosol and cationic polymer |
| JP6966667B2 (en) * | 2019-08-27 | 2021-11-17 | 参天製薬株式会社 | Aqueous ophthalmic composition containing diquafosol or a salt thereof, and polyvinylpyrrolidone. |
-
2020
- 2020-08-25 JP JP2021521065A patent/JP6966667B2/en active Active
- 2020-08-25 MY MYPI2022001012A patent/MY209059A/en unknown
- 2020-08-25 KR KR1020227009546A patent/KR102656181B1/en active Active
- 2020-08-25 PH PH1/2022/550474A patent/PH12022550474A1/en unknown
- 2020-08-25 CN CN202080059970.2A patent/CN114286670B/en active Active
- 2020-08-25 WO PCT/JP2020/031917 patent/WO2021039748A1/en not_active Ceased
- 2020-08-25 CN CN202311818685.6A patent/CN117771172A/en active Pending
- 2020-08-25 TW TW109128895A patent/TWI848171B/en active
- 2020-08-25 KR KR1020247011257A patent/KR20240049646A/en active Pending
-
2021
- 2021-10-20 JP JP2021171358A patent/JP7614069B2/en active Active
-
2024
- 2024-12-25 JP JP2024228577A patent/JP2025031918A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN114286670B (en) | 2024-01-16 |
| JP2025031918A (en) | 2025-03-07 |
| CN117771172A (en) | 2024-03-29 |
| JP2022003099A (en) | 2022-01-11 |
| CN114286670A (en) | 2022-04-05 |
| TWI848171B (en) | 2024-07-11 |
| KR20220052971A (en) | 2022-04-28 |
| JP7614069B2 (en) | 2025-01-15 |
| JPWO2021039748A1 (en) | 2021-09-30 |
| TW202122094A (en) | 2021-06-16 |
| PH12022550474A1 (en) | 2023-03-06 |
| KR102656181B1 (en) | 2024-04-08 |
| KR20240049646A (en) | 2024-04-16 |
| JP6966667B2 (en) | 2021-11-17 |
| WO2021039748A1 (en) | 2021-03-04 |
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