NL1009437C2 - Extractiewerkwijze. - Google Patents

Extractiewerkwijze. Download PDF

Info

Publication number: NL1009437C2
Authority: NL; Netherlands
Prior art keywords: vegetable material; compound; ginkgo tree; solvent; water
Prior art date: 1998-06-18

Application number

NL1009437A

Other languages

English (en)

Dutch (nl)

Inventor

Henri Marie Ruijten

Original Assignee

Xenobiosis

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-06-18

Filing date

1998-06-18

Publication date

1999-12-21

1998-06-18 Priority to NL1009437A priority Critical patent/NL1009437C2/nl

1998-06-18 Application filed by Xenobiosis filed Critical Xenobiosis

1999-06-18 Priority to ES99929944T priority patent/ES2217770T3/es

1999-06-18 Priority to DE69915290T priority patent/DE69915290T2/de

1999-06-18 Priority to PCT/NL1999/000379 priority patent/WO1999065504A1/en

1999-06-18 Priority to DK99929944T priority patent/DK1087780T3/da

1999-06-18 Priority to AT99929944T priority patent/ATE260668T1/de

1999-06-18 Priority to AU46576/99A priority patent/AU4657699A/en

1999-06-18 Priority to US09/719,901 priority patent/US6759065B1/en

1999-06-18 Priority to KR1020007014387A priority patent/KR100703242B1/ko

1999-06-18 Priority to JP2000554383A priority patent/JP2002518337A/ja

1999-06-18 Priority to EP99929944A priority patent/EP1087780B1/de

1999-06-18 Priority to CNB998088943A priority patent/CN1160088C/zh

1999-12-21 Application granted granted Critical

1999-12-21 Publication of NL1009437C2 publication Critical patent/NL1009437C2/nl

Links

238000000605 extraction Methods 0.000 title claims description 9
238000000034 method Methods 0.000 claims abstract description 24
235000008100 Ginkgo biloba Nutrition 0.000 claims abstract description 21
150000001875 compounds Chemical class 0.000 claims abstract description 19
235000011201 Ginkgo Nutrition 0.000 claims abstract description 18
241000218628 Ginkgo Species 0.000 claims abstract description 18
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 13
239000005418 vegetable material Substances 0.000 claims abstract description 12
239000002904 solvent Substances 0.000 claims abstract description 9
239000007788 liquid Substances 0.000 claims abstract description 7
239000002537 cosmetic Substances 0.000 claims abstract description 4
241000196324 Embryophyta Species 0.000 claims description 11
239000004480 active ingredient Substances 0.000 claims description 6
102000004190 Enzymes Human genes 0.000 claims description 3
108090000790 Enzymes Proteins 0.000 claims description 3
241001090156 Huperzia serrata Species 0.000 claims description 2
210000002421 cell wall Anatomy 0.000 claims description 2
239000000945 filler Substances 0.000 claims description 2
239000008194 pharmaceutical composition Substances 0.000 claims description 2
238000001694 spray drying Methods 0.000 claims description 2
230000000699 topical effect Effects 0.000 claims description 2
238000001471 micro-filtration Methods 0.000 claims 1
239000000203 mixture Substances 0.000 claims 1
238000002360 preparation method Methods 0.000 abstract description 7
IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract description 6
229910052757 nitrogen Inorganic materials 0.000 abstract description 3
239000000825 pharmaceutical preparation Substances 0.000 abstract description 3
229930184727 ginkgolide Natural products 0.000 description 5
CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 4
229930003935 flavonoid Natural products 0.000 description 4
150000002215 flavonoids Chemical class 0.000 description 4
235000017173 flavonoids Nutrition 0.000 description 4
ZWEHNKRNPOVVGH-UHFFFAOYSA-N 2-Butanone Chemical compound CCC(C)=O ZWEHNKRNPOVVGH-UHFFFAOYSA-N 0.000 description 3
244000194101 Ginkgo biloba Species 0.000 description 3
OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
239000000463 material Substances 0.000 description 3
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
MOLPUWBMSBJXER-YDGSQGCISA-N bilobalide Chemical compound O([C@H]1OC2=O)C(=O)[C@H](O)[C@@]11[C@@](C(C)(C)C)(O)C[C@H]3[C@@]21CC(=O)O3 MOLPUWBMSBJXER-YDGSQGCISA-N 0.000 description 2
238000001914 filtration Methods 0.000 description 2
150000002576 ketones Chemical class 0.000 description 2
150000003839 salts Chemical class 0.000 description 2
239000007787 solid Substances 0.000 description 2
208000024827 Alzheimer disease Diseases 0.000 description 1
244000269722 Thea sinensis Species 0.000 description 1
GAMYVSCDDLXAQW-AOIWZFSPSA-N Thermopsosid Natural products O(C)c1c(O)ccc(C=2Oc3c(c(O)cc(O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@H](CO)O4)c3)C(=O)C=2)c1 GAMYVSCDDLXAQW-AOIWZFSPSA-N 0.000 description 1
BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 description 1
229910052921 ammonium sulfate Inorganic materials 0.000 description 1
235000011130 ammonium sulphate Nutrition 0.000 description 1
125000004432 carbon atom Chemical group C* 0.000 description 1
210000004027 cell Anatomy 0.000 description 1
239000001913 cellulose Substances 0.000 description 1
229920002678 cellulose Polymers 0.000 description 1
238000005119 centrifugation Methods 0.000 description 1
238000004090 dissolution Methods 0.000 description 1
230000007613 environmental effect Effects 0.000 description 1
230000002349 favourable effect Effects 0.000 description 1
229930003944 flavone Natural products 0.000 description 1
150000002212 flavone derivatives Chemical class 0.000 description 1
235000011949 flavones Nutrition 0.000 description 1
239000007789 gas Substances 0.000 description 1
150000002611 lead compounds Chemical class 0.000 description 1
238000002156 mixing Methods 0.000 description 1
239000004570 mortar (masonry) Substances 0.000 description 1
239000003960 organic solvent Substances 0.000 description 1
230000001590 oxidative effect Effects 0.000 description 1
238000007911 parenteral administration Methods 0.000 description 1
229910052573 porcelain Inorganic materials 0.000 description 1
238000001556 precipitation Methods 0.000 description 1
230000002035 prolonged effect Effects 0.000 description 1
238000000746 purification Methods 0.000 description 1
239000007921 spray Substances 0.000 description 1
VHBFFQKBGNRLFZ-UHFFFAOYSA-N vitamin p Natural products O1C2=CC=CC=C2C(=O)C=C1C1=CC=CC=C1 VHBFFQKBGNRLFZ-UHFFFAOYSA-N 0.000 description 1
238000010626 work up procedure Methods 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/16—Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9741—Pteridophyta [ferns]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9771—Ginkgophyta, e.g. Ginkgoaceae [Ginkgo family]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Natural Medicines & Medicinal Plants (AREA)
Engineering & Computer Science (AREA)
Microbiology (AREA)
Botany (AREA)
Biotechnology (AREA)
Mycology (AREA)
Epidemiology (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Chemical & Material Sciences (AREA)
Medical Informatics (AREA)
Alternative & Traditional Medicine (AREA)
Birds (AREA)
Dermatology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicines Containing Plant Substances (AREA)
Cosmetics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Extraction Or Liquid Replacement (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Compounds Of Unknown Constitution (AREA)

NL1009437A 1998-06-18 1998-06-18 Extractiewerkwijze. NL1009437C2 (nl)

Priority Applications (12)

Application Number	Priority Date	Filing Date	Title
NL1009437A NL1009437C2 (nl)	1998-06-18	1998-06-18	Extractiewerkwijze.
DE69915290T DE69915290T2 (de)	1998-06-18	1999-06-18	Verfahren zur extraktion eines bestandteiles von pflanzenmaterial
PCT/NL1999/000379 WO1999065504A1 (en)	1998-06-18	1999-06-18	Extraction method, pharmaceutical composition and a cosmetic composition
DK99929944T DK1087780T3 (da)	1998-06-18	1999-06-18	Fremgangsmåde til ekstrahering af en forbindelse fra et vegetabilsk materiale
ES99929944T ES2217770T3 (es)	1998-06-18	1999-06-18	Metodo de extraccion de un compuesto a partir de material vegetal.
AT99929944T ATE260668T1 (de)	1998-06-18	1999-06-18	Verfahren zur extraktion eines bestandteiles von pflanzenmaterial
AU46576/99A AU4657699A (en)	1998-06-18	1999-06-18	Extraction method, pharmaceutical composition and a cosmetic composition
US09/719,901 US6759065B1 (en)	1998-06-18	1999-06-18	Extraction method, pharmaceutical composition and a cosmetic composition
KR1020007014387A KR100703242B1 (ko)	1998-06-18	1999-06-18	식물성 물질로부터 화합물을 추출하는 방법
JP2000554383A JP2002518337A (ja)	1998-06-18	1999-06-18	抽出方法、薬剤成分および美容成分
EP99929944A EP1087780B1 (de)	1998-06-18	1999-06-18	Verfahren zur extraktion eines bestandteiles von pflanzenmaterial
CNB998088943A CN1160088C (zh)	1998-06-18	1999-06-18	药物组合物和化妆品组合物的萃取方法

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
NL1009437A NL1009437C2 (nl)	1998-06-18	1998-06-18	Extractiewerkwijze.
NL1009437		1998-06-18

Publications (1)

Publication Number	Publication Date
NL1009437C2 true NL1009437C2 (nl)	1999-12-21

Family

ID=19767340

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NL1009437A NL1009437C2 (nl)	1998-06-18	1998-06-18	Extractiewerkwijze.

Country Status (12)

Country	Link
US (1)	US6759065B1 (de)
EP (1)	EP1087780B1 (de)
JP (1)	JP2002518337A (de)
KR (1)	KR100703242B1 (de)
CN (1)	CN1160088C (de)
AT (1)	ATE260668T1 (de)
AU (1)	AU4657699A (de)
DE (1)	DE69915290T2 (de)
DK (1)	DK1087780T3 (de)
ES (1)	ES2217770T3 (de)
NL (1)	NL1009437C2 (de)
WO (1)	WO1999065504A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2006026713A2 (en) *	2004-08-31	2006-03-09	Tracie Martyn International, Llc	Topical benfotiamine and pyridoxamine compositions
US10864525B1 (en) *	2017-05-26	2020-12-15	Cryocann USA Corporation	System and method for cryogenic separation of plant material
CN109954292A (zh) *	2017-12-25	2019-07-02	山东坦途农业科技有限公司	药材的提取工艺
US11541329B2 (en)	2021-01-29	2023-01-03	Vitalis Extraction Technology Inc.	Liquid carbon dioxide and cosolvent biomass extraction method and system
CN121445651A (zh) *	2026-01-05	2026-02-03	广州莱倩化妆品有限公司	一种控油、遮瑕粉底组合物及其制备方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SU440394A1 (ru) *	1972-08-10	1974-08-25	Институт Ботаники Им.В.Л.Комарова Ан Азербайджанской Сср	Способ получени красител из сырь растительного происхождени
EP0431535A1 (de) *	1989-12-04	1991-06-12	Dr. Willmar Schwabe GmbH & Co.	Extrakt von Ginkgo biloba-Blättern, sein Verfahren zur Herstellung und Arzneimittel, die es enthalten
EP0477968A1 (de) *	1990-09-28	1992-04-01	Dr. Willmar Schwabe GmbH & Co.	Extrakt aus Ginkgo biloba-Blättern, insbesondere für intravenöse Injektionen oder Infusionen, ein Verfahren zur Herstellung des Extraktes und Ampullenzubereitungen, die diesen Extrakt enthalten
WO1996039812A2 (en) *	1995-06-07	1996-12-19	Phyton, Inc.	Cryopreservation of diverse plant cells

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IL81000A0 (en) *	1985-12-20	1987-03-31	Angio Medical Corp	Method for obtaining substances from animal or plants
US4831133A (en) *	1987-05-01	1989-05-16	Allelix, Inc.	Extraction of alkaloids of Catharanthus roseus tissue
US5352777A (en) *	1990-12-26	1994-10-04	Pioneer Hi-Bred International, Inc.	DNA isolation from animal cells
JPH0690723A (ja) *	1992-09-14	1994-04-05	Kanpou Iyaku Kenkyu Shinko Zaidan	杜仲飲料の製造方法
JP3518882B2 (ja) *	1993-11-12	2004-04-12	ダイセル化学工業株式会社	イチョウエキス及びその製造法
CN1125725A (zh) *	1994-12-28	1996-07-03	中国科学院上海药物研究所	一类海克林碱衍生物及它的用途
JPH08208496A (ja) *	1995-02-03	1996-08-13	Akihiro Nagashima	成分抽出用植物加工方法
CN1167153A (zh) *	1997-06-27	1997-12-10	武汉大学	银杏发根的转化及其无性繁殖系的建立
CN1290349A (zh) *	1997-10-23	2001-04-04	法玛普林特公司	药用级银杏

1998
- 1998-06-18 NL NL1009437A patent/NL1009437C2/nl not_active IP Right Cessation
1999
- 1999-06-18 US US09/719,901 patent/US6759065B1/en not_active Expired - Fee Related
- 1999-06-18 EP EP99929944A patent/EP1087780B1/de not_active Expired - Lifetime
- 1999-06-18 KR KR1020007014387A patent/KR100703242B1/ko not_active Expired - Fee Related
- 1999-06-18 WO PCT/NL1999/000379 patent/WO1999065504A1/en not_active Ceased
- 1999-06-18 AU AU46576/99A patent/AU4657699A/en not_active Abandoned
- 1999-06-18 DK DK99929944T patent/DK1087780T3/da active
- 1999-06-18 DE DE69915290T patent/DE69915290T2/de not_active Expired - Lifetime
- 1999-06-18 JP JP2000554383A patent/JP2002518337A/ja active Pending
- 1999-06-18 AT AT99929944T patent/ATE260668T1/de not_active IP Right Cessation
- 1999-06-18 CN CNB998088943A patent/CN1160088C/zh not_active Expired - Fee Related
- 1999-06-18 ES ES99929944T patent/ES2217770T3/es not_active Expired - Lifetime

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SU440394A1 (ru) *	1972-08-10	1974-08-25	Институт Ботаники Им.В.Л.Комарова Ан Азербайджанской Сср	Способ получени красител из сырь растительного происхождени
EP0431535A1 (de) *	1989-12-04	1991-06-12	Dr. Willmar Schwabe GmbH & Co.	Extrakt von Ginkgo biloba-Blättern, sein Verfahren zur Herstellung und Arzneimittel, die es enthalten
EP0477968A1 (de) *	1990-09-28	1992-04-01	Dr. Willmar Schwabe GmbH & Co.	Extrakt aus Ginkgo biloba-Blättern, insbesondere für intravenöse Injektionen oder Infusionen, ein Verfahren zur Herstellung des Extraktes und Ampullenzubereitungen, die diesen Extrakt enthalten
WO1996039812A2 (en) *	1995-06-07	1996-12-19	Phyton, Inc.	Cryopreservation of diverse plant cells

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Section Ch Week 7529, Derwent World Patents Index; Class D13, AN 75-49034W, XP002095997 *

Also Published As

Publication number	Publication date
ES2217770T3 (es)	2004-11-01
CN1160088C (zh)	2004-08-04
KR100703242B1 (ko)	2007-04-20
KR20010052992A (ko)	2001-06-25
DE69915290D1 (de)	2004-04-08
AU4657699A (en)	2000-01-05
EP1087780B1 (de)	2004-03-03
ATE260668T1 (de)	2004-03-15
US6759065B1 (en)	2004-07-06
WO1999065504A1 (en)	1999-12-23
DE69915290T2 (de)	2005-03-24
JP2002518337A (ja)	2002-06-25
DK1087780T3 (da)	2004-07-12
CN1310624A (zh)	2001-08-29
EP1087780A1 (de)	2001-04-04

Legal Events

Date	Code	Title	Description
2000-02-01	PD2B	A search report has been drawn up
2001-07-02	SD	Assignments of patents	Owner name: STICHTING BIO CYBERNETICS
2005-05-02	SD	Assignments of patents	Owner name: XENOBIOSIS INTERNATIONAL B.V.
2012-01-11	V1	Lapsed because of non-payment of the annual fee	Effective date: 20120101

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