|
GB1570494A
(en)
*
|
1975-11-28 |
1980-07-02 |
Ici Ltd |
Thienopyrimidine derivatives and their use as pesticides
|
|
GB8912335D0
(en)
*
|
1989-05-30 |
1989-07-12 |
Smithkline Beckman Intercredit |
Compounds
|
|
US5280026A
(en)
*
|
1989-05-30 |
1994-01-18 |
Smithkline Beecham Intercredit B.V. |
Thienopyrimidines
|
|
US5098902A
(en)
*
|
1991-03-18 |
1992-03-24 |
Warner-Lambert Company |
Method of treating neurodegenerative diseases
|
|
US6187777B1
(en)
|
1998-02-06 |
2001-02-13 |
Amgen Inc. |
Compounds and methods which modulate feeding behavior and related diseases
|
|
US6608053B2
(en)
*
|
2000-04-27 |
2003-08-19 |
Yamanouchi Pharmaceutical Co., Ltd. |
Fused heteroaryl derivatives
|
|
GB0423653D0
(en)
*
|
2004-10-25 |
2004-11-24 |
Piramed Ltd |
Pharmaceutical compounds
|
|
CN101163706A
(zh)
*
|
2005-04-21 |
2008-04-16 |
贝林格尔·英格海姆国际有限公司 |
用于治疗炎性疾病的二氢噻吩并嘧啶
|
|
EP1847543A1
(de)
|
2006-04-19 |
2007-10-24 |
Boehringer Ingelheim Pharma GmbH & Co. KG |
Dihydrothienopyrimidine zur Behandlung von entzündlichen Erkrankungen
|
|
CN101479274B
(zh)
*
|
2006-04-26 |
2013-06-12 |
霍夫曼-拉罗奇有限公司 |
药用化合物
|
|
RU2439074C2
(ru)
*
|
2006-04-26 |
2012-01-10 |
Ф. Хоффманн-Ля Рош Аг |
ПРОИЗВОДНОЕ ТИЕНО[3,2-d]ПИРИМИДИНА В КАЧЕСТВЕ ИНГИБИТОРА ФОСФАТИДИЛИНОЗИТОЛ-3-КИНАЗЫ (РI3К)
|
|
JP5291616B2
(ja)
*
|
2006-04-26 |
2013-09-18 |
ジェネンテック, インコーポレイテッド |
ホスホイノシチド3−キナーゼ抑制剤化合物およびその使用方法
|
|
JP5500990B2
(ja)
*
|
2006-12-07 |
2014-05-21 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
ホスホイノシチド3−キナーゼ阻害剤化合物及び使用方法
|
|
WO2008070740A1
(en)
*
|
2006-12-07 |
2008-06-12 |
F.Hoffmann-La Roche Ag |
Phosphoinositide 3-kinase inhibitor compounds and methods of use
|
|
ES2399774T3
(es)
|
2007-09-24 |
2013-04-03 |
Genentech, Inc. |
Compuestos de tiazolopirimidina inhibidores de PI3K y métodos de uso
|
|
CA2702524A1
(en)
|
2007-10-19 |
2009-04-23 |
Boehringer Ingelheim International Gmbh |
Heterocycle-substituted piperazino-dihydrothienopyrimidines
|
|
CN104069112A
(zh)
*
|
2007-10-19 |
2014-10-01 |
贝林格尔.英格海姆国际有限公司 |
取代的哌啶子基-二氢噻吩并嘧啶
|
|
CA2702518A1
(en)
|
2007-10-19 |
2009-04-23 |
Boehringer Ingelheim International Gmbh |
New piperazino-dihydrothienopyrimidine derivatives
|
|
EP2214675B1
(en)
|
2007-10-25 |
2013-11-20 |
Genentech, Inc. |
Process for making thienopyrimidine compounds
|
|
GB0721095D0
(en)
*
|
2007-10-26 |
2007-12-05 |
Piramed Ltd |
Pharmaceutical compounds
|
|
CN102369011A
(zh)
|
2009-03-12 |
2012-03-07 |
健泰科生物技术公司 |
用于治疗造血恶性肿瘤的磷酸肌醇3-激酶抑制剂化合物与化学治疗剂的组合
|
|
EP2451811A1
(en)
*
|
2009-05-27 |
2012-05-16 |
F. Hoffmann-La Roche AG |
Bicyclic indole-pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use
|
|
SG175708A1
(en)
*
|
2009-05-27 |
2011-12-29 |
Genentech Inc |
Bicyclic pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use
|
|
NZ599939A
(en)
*
|
2009-10-12 |
2014-02-28 |
Hoffmann La Roche |
Combinations of a pi3k inhibitor and a mek inhibitor
|
|
MX2012011887A
(es)
|
2010-04-16 |
2012-11-30 |
Genentech Inc |
Foxo 3a como biomarcador predictivo para la eficacia del inhibidor de la via de quinasa pi3k/akt.
|
|
WO2012088254A1
(en)
|
2010-12-22 |
2012-06-28 |
Genentech, Inc. |
Autophagy inducer and inhibitor combination therapy for the treatment of neoplasms
|
|
US9802954B2
(en)
|
2011-08-24 |
2017-10-31 |
Boehringer Ingelheim International Gmbh |
Piperidino-dihydrothienopyrimidine sulfoxides and their use for treating COPD and asthma
|
|
US20130059866A1
(en)
|
2011-08-24 |
2013-03-07 |
Boehringer Ingelheim International Gmbh |
Novel piperidino-dihydrothienopyrimidine sulfoxides and their use for treating copd and asthma
|
|
CA2901126C
(en)
|
2013-02-25 |
2022-01-25 |
Genentech, Inc. |
Methods and compositions for detecting and treating drug resistant akt mutant
|
|
MA53043B2
(fr)
*
|
2018-10-01 |
2024-05-31 |
Genzyme Corp |
Dérivés de thiéno[3,2-b]pyridine utilisés en tant qu'inhibiteurs de l'udp-glycosyltransférase et procédés d'utilisation
|
|
GB202014736D0
(en)
*
|
2020-09-18 |
2020-11-04 |
Imperial College Innovations Ltd |
Novel compounds and their use in therapy
|